Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis

Abstract:
Iranian researchers from Nanobiotechnology Department of the University of Tehran designed a nanosensor that has the highest reported value of sensitivity in the diagnosis of cancer.

Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis

Tehran, Iran | Posted on July 19th, 2014

The nanosensor enables diagnosis of cancer in its early stages through a fast, simple and cheap method.

The presence of DNA chains caused by cellular death in blood is a very good opportunity to detect them and to determine the changes in methylation to obtain early diagnosis of cancer.

According to Mehdi Dadmehr, one of the researchers, very low concentration of DNA in blood is one of the most important challenges for the detection of the changes, which requires a very sensitive detection system. Normal methods that are currently used all over the world are usually based on DNA proliferation after pretreatment, which results in the degradation of over 90% of DNA during the test.

In this research, the possibility to detect changes in methylation and even the percentage of methylation in more accurate manner has been provided by using a nanosystem based on fluorescent probe. The nanoysystem has very high sensitivity to the extent that it detects concentrations of DNA at about 0.3 femtomolar (3*10-16). This amount has so far been reported as the highest value of detection limit in comparison with all other methods being used across the world.

Iron oxide magnetic nanoparticles with gold coating have been used in the production of the nanosensor. Dadmehr explained the advantages of this research, and said, "In addition to enabling early diagnosis of cancer, the nanosensor facilitates target gene-therapy of the cancer by detecting the type of the methylized gene."

Results of the research have been published in Biosensors and Bioelectronics, vol. 60, issue 1, April 2014, pp. 35-44.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Keysight Technologies Shifts to Direct Sales of High-Performance Products in North America March 3rd, 2015

Cambrios and Heraeus Jointly Create New, High-Conductivity Transparent Conductors: Two Companies' Combined Products Dramatically Extend Flexible Substrate Capabilities for Next-Generation Mass-Market Technology Products March 3rd, 2015

The taming of magnetic vortices: Unified theory for skyrmion-materials March 3rd, 2015

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

Nanomedicine

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

Pens filled with high-tech inks for do-it-yourself sensors March 3rd, 2015

New nanodevice defeats drug resistance: Tiny particles embedded in gel can turn off drug-resistance genes, then release cancer drugs March 2nd, 2015

New Hopes for Treatment of Intestine Cancer by Edible Nanodrug March 2nd, 2015

Sensors

Pens filled with high-tech inks for do-it-yourself sensors March 3rd, 2015

Penn researchers develop new technique for making molybdenum disulfide: Extra control over monolayer material with advantages over graphene February 19th, 2015

Researchers build atomically thin gas and chemical sensors: Sensors made of molybdenum disulfide are small, thin and have a high level of selectivity when detecting gases and chemicals February 19th, 2015

Production of Biosensor in Iran to Detect Oxalic Acid February 18th, 2015

Discoveries

The taming of magnetic vortices: Unified theory for skyrmion-materials March 3rd, 2015

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

Pens filled with high-tech inks for do-it-yourself sensors March 3rd, 2015

Black phosphorus is new 'wonder material' for improving optical communication March 3rd, 2015

Announcements

The taming of magnetic vortices: Unified theory for skyrmion-materials March 3rd, 2015

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

Pens filled with high-tech inks for do-it-yourself sensors March 3rd, 2015

Black phosphorus is new 'wonder material' for improving optical communication March 3rd, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

The taming of magnetic vortices: Unified theory for skyrmion-materials March 3rd, 2015

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

Pens filled with high-tech inks for do-it-yourself sensors March 3rd, 2015

Black phosphorus is new 'wonder material' for improving optical communication March 3rd, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE