Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis

Abstract:
Iranian researchers from Nanobiotechnology Department of the University of Tehran designed a nanosensor that has the highest reported value of sensitivity in the diagnosis of cancer.

Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis

Tehran, Iran | Posted on July 19th, 2014

The nanosensor enables diagnosis of cancer in its early stages through a fast, simple and cheap method.

The presence of DNA chains caused by cellular death in blood is a very good opportunity to detect them and to determine the changes in methylation to obtain early diagnosis of cancer.

According to Mehdi Dadmehr, one of the researchers, very low concentration of DNA in blood is one of the most important challenges for the detection of the changes, which requires a very sensitive detection system. Normal methods that are currently used all over the world are usually based on DNA proliferation after pretreatment, which results in the degradation of over 90% of DNA during the test.

In this research, the possibility to detect changes in methylation and even the percentage of methylation in more accurate manner has been provided by using a nanosystem based on fluorescent probe. The nanoysystem has very high sensitivity to the extent that it detects concentrations of DNA at about 0.3 femtomolar (3*10-16). This amount has so far been reported as the highest value of detection limit in comparison with all other methods being used across the world.

Iron oxide magnetic nanoparticles with gold coating have been used in the production of the nanosensor. Dadmehr explained the advantages of this research, and said, "In addition to enabling early diagnosis of cancer, the nanosensor facilitates target gene-therapy of the cancer by detecting the type of the methylized gene."

Results of the research have been published in Biosensors and Bioelectronics, vol. 60, issue 1, April 2014, pp. 35-44.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Switching with molecules: Molecular switch will facilitate the development of pioneering electro-optical devices May 25th, 2018

Tunable diamond string may hold key to quantum memory: A process similar to guitar tuning improves storage time of quantum memory May 24th, 2018

Remote control of transport through nanopores: New study outlines key factors affecting the transfer of molecules through biological channels May 24th, 2018

2018 Kavli Prizes in Astrophysics, Nanoscience, and Neuroscience to be Announced Live on May 31: Live announcement at the Norwegian Academy of Science and Letters to be streamed live at World Science Festival Event May 24th, 2018

Nanomedicine

Remote control of transport through nanopores: New study outlines key factors affecting the transfer of molecules through biological channels May 24th, 2018

New blood test rapidly detects signs of pancreatic cancer May 17th, 2018

Elastic microspheres expand understanding of embryonic development and cancer cells May 15th, 2018

Nanomedicine -- Targeting cancer cells with sugars May 14th, 2018

Sensors

Magnesium magnificent for plasmonic applications: Rice University, University of Cambridge synthesize and test nanoparticles of abundant material May 22nd, 2018

Strain improves performance of atomically thin semiconductor material May 11th, 2018

Salt boosts creation of 2-D materials: Rice University scientists show how salt lowers reaction temperatures to make novel materials April 18th, 2018

Doing the nano-shimmy: New device modulates light and amplifies tiny signals April 12th, 2018

Discoveries

Switching with molecules: Molecular switch will facilitate the development of pioneering electro-optical devices May 25th, 2018

Tunable diamond string may hold key to quantum memory: A process similar to guitar tuning improves storage time of quantum memory May 24th, 2018

Remote control of transport through nanopores: New study outlines key factors affecting the transfer of molecules through biological channels May 24th, 2018

'Spooky action at a distance': Researchers develop module for quantum repeater May 23rd, 2018

Announcements

Switching with molecules: Molecular switch will facilitate the development of pioneering electro-optical devices May 25th, 2018

Tunable diamond string may hold key to quantum memory: A process similar to guitar tuning improves storage time of quantum memory May 24th, 2018

Remote control of transport through nanopores: New study outlines key factors affecting the transfer of molecules through biological channels May 24th, 2018

2018 Kavli Prizes in Astrophysics, Nanoscience, and Neuroscience to be Announced Live on May 31: Live announcement at the Norwegian Academy of Science and Letters to be streamed live at World Science Festival Event May 24th, 2018

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Switching with molecules: Molecular switch will facilitate the development of pioneering electro-optical devices May 25th, 2018

Tunable diamond string may hold key to quantum memory: A process similar to guitar tuning improves storage time of quantum memory May 24th, 2018

Remote control of transport through nanopores: New study outlines key factors affecting the transfer of molecules through biological channels May 24th, 2018

'Spooky action at a distance': Researchers develop module for quantum repeater May 23rd, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project