Home > Press > Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis
Abstract:
Iranian researchers from Nanobiotechnology Department of the University of Tehran designed a nanosensor that has the highest reported value of sensitivity in the diagnosis of cancer.
Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis
Tehran, Iran | Posted on July 19th, 2014 The nanosensor enables diagnosis of cancer in its early stages through a fast, simple and cheap method.
The presence of DNA chains caused by cellular death in blood is a very good opportunity to detect them and to determine the changes in methylation to obtain early diagnosis of cancer.
According to Mehdi Dadmehr, one of the researchers, very low concentration of DNA in blood is one of the most important challenges for the detection of the changes, which requires a very sensitive detection system. Normal methods that are currently used all over the world are usually based on DNA proliferation after pretreatment, which results in the degradation of over 90% of DNA during the test.
In this research, the possibility to detect changes in methylation and even the percentage of methylation in more accurate manner has been provided by using a nanosystem based on fluorescent probe. The nanoysystem has very high sensitivity to the extent that it detects concentrations of DNA at about 0.3 femtomolar (3*10-16). This amount has so far been reported as the highest value of detection limit in comparison with all other methods being used across the world.
Iron oxide magnetic nanoparticles with gold coating have been used in the production of the nanosensor. Dadmehr explained the advantages of this research, and said, "In addition to enabling early diagnosis of cancer, the nanosensor facilitates target gene-therapy of the cancer by detecting the type of the methylized gene."
Results of the research have been published in Biosensors and Bioelectronics, vol. 60, issue 1, April 2014, pp. 35-44.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Optical switching at record speeds opens door for ultrafast, light-based electronics and computers: March 24th, 2023
Robot caterpillar demonstrates new approach to locomotion for soft robotics March 24th, 2023
Semiconductor lattice marries electrons and magnetic moments March 24th, 2023
Light meets deep learning: computing fast enough for next-gen AI March 24th, 2023
Nanomedicine
Getting drugs across the blood-brain barrier using nanoparticles March 3rd, 2023
Scientists push the boundaries of manipulating light at the submicroscopic level March 3rd, 2023
Sensors
Scientists push the boundaries of manipulating light at the submicroscopic level March 3rd, 2023
Discoveries
New experiment translates quantum information between technologies in an important step for the quantum internet March 24th, 2023
Graphene grows – and we can see it March 24th, 2023
HKUMed invents a novel two-dimensional (2D) ultrasound-responsive antibacterial nano-sheets to effectively address bone tissue infection March 24th, 2023
A universal HCl-assistant powder-to-powder strategy for preparing lead-free perovskites March 24th, 2023
Announcements
Robot caterpillar demonstrates new approach to locomotion for soft robotics March 24th, 2023
Semiconductor lattice marries electrons and magnetic moments March 24th, 2023
Light meets deep learning: computing fast enough for next-gen AI March 24th, 2023
Bilayer PET/PVDF substrate-reinforced solid polymer electrolyte improves solid-state lithium metal battery performance March 24th, 2023
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
HKUMed invents a novel two-dimensional (2D) ultrasound-responsive antibacterial nano-sheets to effectively address bone tissue infection March 24th, 2023
A universal HCl-assistant powder-to-powder strategy for preparing lead-free perovskites March 24th, 2023
Optical switching at record speeds opens door for ultrafast, light-based electronics and computers: March 24th, 2023
Robot caterpillar demonstrates new approach to locomotion for soft robotics March 24th, 2023
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||