Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Production of Non-Virus Nanocarriers with Highest Amount of Gene Delivery

Abstract:
Iranian researchers from Tarbiat Modarres University changed the liposome production process and increased the amount of genes entrapped in the structure of these nanocarriers.

Production of Non-Virus Nanocarriers with Highest Amount of Gene Delivery

Tehran, Iran | Posted on July 17th, 2014

The non-virus nanocarriers have neutral structure and very high stability and they protect entrapped genes against degrading enzymes.

In this research, some changes were made in the synthesis of liposomes and nanocarriers were produced that can entrap DNA molecules with very high efficiency (98%) in their absolutely neutral structure. The results have so far been reported only for cationic liposomes that are highly toxic and can only be used in-vivo.

The nanostructure is very stable, to the extent that no release of DNA has been observed from it after six months. DNA is trapped in aqueous environment inside the liposome. Therefore, degrading enzymes are not able to degrade DNA molecule, and as a result, DNA has very high stability inside the structure.

Among other advantages of the designed nanocarrier, mention can be made of its very high ability in gene delivery to bacterium cell. Therefore, it can be used in the treatment of infections caused by bacteria, which are resistant to medications. The nanostructure can also be used as an appropriate carrier to delivery medications in the treatment of human diseases. The research team is currently carrying out studies on gene delivery to bacterium cells through this system.

Taking into account the obtained results, the researchers are hopeful that liposomes derived from cellular membrane will have important role in drug and gene delivery in the near future; therefore, they will take the place of toxic cationic carriers that are currently used.

Results of the research have been published in Molecular Biotechnology, vol. 55, issue 2, October 2013, pp. 120-130.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Novel Rocket Design Flight Tested: New Rocket Propellant and Motor Design Offers High Performance and Safety October 23rd, 2014

MEMS & Sensors Technology Showcase: Finalists Announced for MEMS Executive Congress US 2014 October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

SUNY Polytechnic Institute Invites the Public to Attend its Popular Statewide 'NANOvember' Series of Outreach and Educational Events October 23rd, 2014

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Bipolar Disorder Discovery at the Nano Level: Tiny structures found in brain synapses help scientists better understand disorder October 22nd, 2014

Discoveries

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Nanoparticle technology triples the production of biogas October 23rd, 2014

SUNY Polytechnic Institute Invites the Public to Attend its Popular Statewide 'NANOvember' Series of Outreach and Educational Events October 23rd, 2014

Advancing thin film research with nanostructured AZO: Innovnano’s unique and cost-effective AZO sputtering targets for the production of transparent conducting oxides October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Nanobiotechnology

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Mechanism behind nature's sparkles revealed October 22nd, 2014

‘Designer’ nanodevice could improve treatment options for cancer sufferers October 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE