Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button

Home > Press > Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Abstract:
Iranian pharmaceutical researchers from Mashhad University of Medical Sciences obtained promising results for the production of a vaccine to treat Leishmaniasis.

Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Tehran, Iran | Posted on April 30th, 2014

The vaccine has a simple and cost-effective production method, and if the research stages are complete, it will create hope for the industrial production of the vaccine in the country.

Dr. Mahmood Reza Ja'fari, a member of the Scientific Board of Mashhad University of Medical Sciences, explained about the research, and said, "Leishmaniasis is one of the common diseases between human and animals, which is caused by parasites. Depending on the parasite type and immunity respond of the host, the severity of the diseases varies from a limited skin infection to fatal level. Although numerous researches have so far been carried out all over the world, there is still no vaccine for Leishmaniasis in the market. Therefore, the invention of a vaccine for Leishmaniasis was out main objective of this research."

Injection of the vaccine into a group of mice (BALB/c mice) triggered their cell immune system. The produced vaccine is very effective in the protection of the mice against the parasitic disease. BALB/c mice are much more sensitive to Leishmaniasis parasite; therefore, if a vaccine is effective on the mice, it will surely be more effective on humans who are stronger against Leishmaniasis infection.

According to Dr. Ja'fari, since the produced liposome is small in size, most of them are absorbed by lymphatic system subcutaneous injection, and they are gathered in lymphatic nodes by APC cells with very high performance. Then, antigens dissolved in liposome are released in APC cell. It triggers cell immune system, and protects mice against the challenge with the living parasite of Leishmaniasis. The researchers are currently studying the stabilization of the produced vaccine. After achieving this goal, the liposome should be produced in clean environment and the required certificates should be attained. Then, clinical tests will be carried out on patients.

All the requirements for industrial production of the vaccine are available in the country. Results of the research have been published in Acta Tropica, vol. 128, issue 3, August 2013, pp. 528-535.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Nanomedicine

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Pixel-array quantum cascade detector paves the way for portable thermal imaging devices: Research team from TU-Wien Center for Micro- and Nanostructures have developed a new 'cooler' sensing instrument thereby increasing energy-efficiency and enhancing mobility for diagnostic tes July 28th, 2016

Starpharma initiates new DEPô drug delivery program with AstraZeneca July 27th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Discoveries

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Announcements

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Scientists change properties of zeolites to improve hemodialysis July 29th, 2016

Novel state of matter: Observation of a quantum spin liquid July 29th, 2016

A new type of quantum bits July 29th, 2016

Lonely atoms, happily reunited July 29th, 2016

Industrial

Dirty to drinkable: Engineers develop novel hybrid nanomaterials to transform water July 28th, 2016

Scientists move 1 step closer to creating an invisibility cloak July 15th, 2016

Yale researchersí technology turns wasted heat into power June 27th, 2016

Industrial Nanotech, Inc. Signs Agreement With and Receives First Purchase Order from Major New Customer in China June 6th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic