Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Abstract:
Iranian pharmaceutical researchers from Mashhad University of Medical Sciences obtained promising results for the production of a vaccine to treat Leishmaniasis.

Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Tehran, Iran | Posted on April 30th, 2014

The vaccine has a simple and cost-effective production method, and if the research stages are complete, it will create hope for the industrial production of the vaccine in the country.

Dr. Mahmood Reza Ja'fari, a member of the Scientific Board of Mashhad University of Medical Sciences, explained about the research, and said, "Leishmaniasis is one of the common diseases between human and animals, which is caused by parasites. Depending on the parasite type and immunity respond of the host, the severity of the diseases varies from a limited skin infection to fatal level. Although numerous researches have so far been carried out all over the world, there is still no vaccine for Leishmaniasis in the market. Therefore, the invention of a vaccine for Leishmaniasis was out main objective of this research."

Injection of the vaccine into a group of mice (BALB/c mice) triggered their cell immune system. The produced vaccine is very effective in the protection of the mice against the parasitic disease. BALB/c mice are much more sensitive to Leishmaniasis parasite; therefore, if a vaccine is effective on the mice, it will surely be more effective on humans who are stronger against Leishmaniasis infection.

According to Dr. Ja'fari, since the produced liposome is small in size, most of them are absorbed by lymphatic system subcutaneous injection, and they are gathered in lymphatic nodes by APC cells with very high performance. Then, antigens dissolved in liposome are released in APC cell. It triggers cell immune system, and protects mice against the challenge with the living parasite of Leishmaniasis. The researchers are currently studying the stabilization of the produced vaccine. After achieving this goal, the liposome should be produced in clean environment and the required certificates should be attained. Then, clinical tests will be carried out on patients.

All the requirements for industrial production of the vaccine are available in the country. Results of the research have been published in Acta Tropica, vol. 128, issue 3, August 2013, pp. 528-535.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Leti to Offer Updates on Silicon Photonics Successes at OFC in LA February 27th, 2015

Moving molecule writes letters: Caging of molecules allows investigation of equilibrium thermodynamics February 27th, 2015

Untangling DNA with a droplet of water, a pipet and a polymer: With the 'rolling droplet technique,' a DNA-injected water droplet rolls like a ball over a platelet, sticking the DNA to the plate surface February 27th, 2015

Maximum Precision in 3D Printing: New complete solution makes additive manufacturing standard for microfabrication February 26th, 2015

Nanomedicine

Untangling DNA with a droplet of water, a pipet and a polymer: With the 'rolling droplet technique,' a DNA-injected water droplet rolls like a ball over a platelet, sticking the DNA to the plate surface February 27th, 2015

Graphene shows potential as novel anti-cancer therapeutic strategy: University of Manchester scientists have used graphene to target and neutralise cancer stem cells while not harming other cells February 26th, 2015

Cutting-edge technology optimizes cancer therapy with nanomedicine drug combinations: UCLA bioengineers develop platform that offers personalized approach to treatment February 24th, 2015

Optical nanoantennas set the stage for a NEMS lab-on-a-chip revolution February 24th, 2015

Discoveries

Leti to Offer Updates on Silicon Photonics Successes at OFC in LA February 27th, 2015

Moving molecule writes letters: Caging of molecules allows investigation of equilibrium thermodynamics February 27th, 2015

Untangling DNA with a droplet of water, a pipet and a polymer: With the 'rolling droplet technique,' a DNA-injected water droplet rolls like a ball over a platelet, sticking the DNA to the plate surface February 27th, 2015

Graphene shows potential as novel anti-cancer therapeutic strategy: University of Manchester scientists have used graphene to target and neutralise cancer stem cells while not harming other cells February 26th, 2015

Announcements

Leti to Offer Updates on Silicon Photonics Successes at OFC in LA February 27th, 2015

Moving molecule writes letters: Caging of molecules allows investigation of equilibrium thermodynamics February 27th, 2015

Untangling DNA with a droplet of water, a pipet and a polymer: With the 'rolling droplet technique,' a DNA-injected water droplet rolls like a ball over a platelet, sticking the DNA to the plate surface February 27th, 2015

Graphene shows potential as novel anti-cancer therapeutic strategy: University of Manchester scientists have used graphene to target and neutralise cancer stem cells while not harming other cells February 26th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Moving molecule writes letters: Caging of molecules allows investigation of equilibrium thermodynamics February 27th, 2015

Untangling DNA with a droplet of water, a pipet and a polymer: With the 'rolling droplet technique,' a DNA-injected water droplet rolls like a ball over a platelet, sticking the DNA to the plate surface February 27th, 2015

Real-time observation of bond formation by using femtosecond X-ray liquidography February 26th, 2015

Graphene shows potential as novel anti-cancer therapeutic strategy: University of Manchester scientists have used graphene to target and neutralise cancer stem cells while not harming other cells February 26th, 2015

Industrial

In quest for better lithium-air batteries, chemists boost carbon's stability: Nanoparticle coatings improve stability, cyclability of '3DOm' carbon February 25th, 2015

Purification of Industrial Wastewater Using Visible-Light Sensitive Photocatalysts February 24th, 2015

Increasing Efficiency of Cooling Devices in Oil, Gas Industries February 21st, 2015

Ligar secures investment from Wallace Corporation to commercialise polymers that pick out good and bad molecules: Ground-breaking science innovation removes molecules in the wrong place from liquids February 15th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE