Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Abstract:
Iranian pharmaceutical researchers from Mashhad University of Medical Sciences obtained promising results for the production of a vaccine to treat Leishmaniasis.

Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Tehran, Iran | Posted on April 30th, 2014

The vaccine has a simple and cost-effective production method, and if the research stages are complete, it will create hope for the industrial production of the vaccine in the country.

Dr. Mahmood Reza Ja'fari, a member of the Scientific Board of Mashhad University of Medical Sciences, explained about the research, and said, "Leishmaniasis is one of the common diseases between human and animals, which is caused by parasites. Depending on the parasite type and immunity respond of the host, the severity of the diseases varies from a limited skin infection to fatal level. Although numerous researches have so far been carried out all over the world, there is still no vaccine for Leishmaniasis in the market. Therefore, the invention of a vaccine for Leishmaniasis was out main objective of this research."

Injection of the vaccine into a group of mice (BALB/c mice) triggered their cell immune system. The produced vaccine is very effective in the protection of the mice against the parasitic disease. BALB/c mice are much more sensitive to Leishmaniasis parasite; therefore, if a vaccine is effective on the mice, it will surely be more effective on humans who are stronger against Leishmaniasis infection.

According to Dr. Ja'fari, since the produced liposome is small in size, most of them are absorbed by lymphatic system subcutaneous injection, and they are gathered in lymphatic nodes by APC cells with very high performance. Then, antigens dissolved in liposome are released in APC cell. It triggers cell immune system, and protects mice against the challenge with the living parasite of Leishmaniasis. The researchers are currently studying the stabilization of the produced vaccine. After achieving this goal, the liposome should be produced in clean environment and the required certificates should be attained. Then, clinical tests will be carried out on patients.

All the requirements for industrial production of the vaccine are available in the country. Results of the research have been published in Acta Tropica, vol. 128, issue 3, August 2013, pp. 528-535.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Researchers uncover secret of nanomaterial that makes harvesting sunlight easier March 29th, 2017

Information storage with a nanoscale twist: Discovery of a novel rotational force inside magnetic vortices makes it easier to design ultrahigh capacity disk drives March 28th, 2017

A big leap toward tinier lines: Self-assembly technique could lead to long-awaited, simple method for making smaller microchip patterns March 27th, 2017

Nanomedicine

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Laser activated gold pyramids could deliver drugs, DNA into cells without harm: Microstructures create temporary pores in cells March 27th, 2017

Researchers make flexible glass for tiny medical devices: Glass can bend over and over again on a nanoscale March 27th, 2017

Cryo-electron microscopy achieves unprecedented resolution using new computational methods March 25th, 2017

Discoveries

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Researchers uncover secret of nanomaterial that makes harvesting sunlight easier March 29th, 2017

Information storage with a nanoscale twist: Discovery of a novel rotational force inside magnetic vortices makes it easier to design ultrahigh capacity disk drives March 28th, 2017

A big leap toward tinier lines: Self-assembly technique could lead to long-awaited, simple method for making smaller microchip patterns March 27th, 2017

Announcements

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Researchers uncover secret of nanomaterial that makes harvesting sunlight easier March 29th, 2017

Information storage with a nanoscale twist: Discovery of a novel rotational force inside magnetic vortices makes it easier to design ultrahigh capacity disk drives March 28th, 2017

ATTOPSEMI Technology Joins FDXcelerator Program to Deliver Advanced Non-Volatile Memory IP to GLOBALFOUNDRIES 22 FDX Technology Platform: Leading-edge I-fuse brings higher reliability, smaller cell size and ease of programmability for consumer, automotive, and IoT applications March 27th, 2017

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Researchers uncover secret of nanomaterial that makes harvesting sunlight easier March 29th, 2017

Information storage with a nanoscale twist: Discovery of a novel rotational force inside magnetic vortices makes it easier to design ultrahigh capacity disk drives March 28th, 2017

Laser activated gold pyramids could deliver drugs, DNA into cells without harm: Microstructures create temporary pores in cells March 27th, 2017

Industrial

Rare-earths become water-repellent only as they age March 22nd, 2017

CRMGroup in Belgium uses a Deben three point bending stage in the development of new steel & coated steel products for automotive and other industrial applications March 21st, 2017

Imaging the inner workings of a sodium-metal sulfide battery for first time: Understanding how the structural and chemical makeup of the material changes during the charge/discharge process could help scientists advance battery design for future energy storage needs March 9th, 2017

Rice lab expands palette for color-changing glass: Nanophotonics team creates low-voltage, multicolor, electrochromic glass March 8th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project