Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Abstract:
Iranian pharmaceutical researchers from Mashhad University of Medical Sciences obtained promising results for the production of a vaccine to treat Leishmaniasis.

Iranian Researchers Make Progress in Production of Leishmaniasis Vaccine

Tehran, Iran | Posted on April 30th, 2014

The vaccine has a simple and cost-effective production method, and if the research stages are complete, it will create hope for the industrial production of the vaccine in the country.

Dr. Mahmood Reza Ja'fari, a member of the Scientific Board of Mashhad University of Medical Sciences, explained about the research, and said, "Leishmaniasis is one of the common diseases between human and animals, which is caused by parasites. Depending on the parasite type and immunity respond of the host, the severity of the diseases varies from a limited skin infection to fatal level. Although numerous researches have so far been carried out all over the world, there is still no vaccine for Leishmaniasis in the market. Therefore, the invention of a vaccine for Leishmaniasis was out main objective of this research."

Injection of the vaccine into a group of mice (BALB/c mice) triggered their cell immune system. The produced vaccine is very effective in the protection of the mice against the parasitic disease. BALB/c mice are much more sensitive to Leishmaniasis parasite; therefore, if a vaccine is effective on the mice, it will surely be more effective on humans who are stronger against Leishmaniasis infection.

According to Dr. Ja'fari, since the produced liposome is small in size, most of them are absorbed by lymphatic system subcutaneous injection, and they are gathered in lymphatic nodes by APC cells with very high performance. Then, antigens dissolved in liposome are released in APC cell. It triggers cell immune system, and protects mice against the challenge with the living parasite of Leishmaniasis. The researchers are currently studying the stabilization of the produced vaccine. After achieving this goal, the liposome should be produced in clean environment and the required certificates should be attained. Then, clinical tests will be carried out on patients.

All the requirements for industrial production of the vaccine are available in the country. Results of the research have been published in Acta Tropica, vol. 128, issue 3, August 2013, pp. 528-535.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Controlling Dynamic Behavior of Carbon Nanosheets in Structures Made Possible July 30th, 2015

Newly-Developed Polymers Control Size of Nanoparticles during Production Process July 30th, 2015

Detecting small metallic contaminants in food via magnetization: A practical metallic-contaminant detecting system using three high-Tc RF superconducting quantum interference devices (SQUIDs) July 29th, 2015

Nanomedicine

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Newly-Developed Polymers Control Size of Nanoparticles during Production Process July 30th, 2015

March 2016; 6th Int'l Conference on Nanostructures in Iran July 29th, 2015

Non-Enzyme Sensor Determines Level of Blood Sugar July 29th, 2015

Discoveries

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Controlling Dynamic Behavior of Carbon Nanosheets in Structures Made Possible July 30th, 2015

Newly-Developed Polymers Control Size of Nanoparticles during Production Process July 30th, 2015

Non-Enzyme Sensor Determines Level of Blood Sugar July 29th, 2015

Announcements

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Controlling Dynamic Behavior of Carbon Nanosheets in Structures Made Possible July 30th, 2015

Newly-Developed Polymers Control Size of Nanoparticles during Production Process July 30th, 2015

Detecting small metallic contaminants in food via magnetization: A practical metallic-contaminant detecting system using three high-Tc RF superconducting quantum interference devices (SQUIDs) July 29th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Controlling Dynamic Behavior of Carbon Nanosheets in Structures Made Possible July 30th, 2015

Newly-Developed Polymers Control Size of Nanoparticles during Production Process July 30th, 2015

Meet the high-performance single-molecule diode: Major milestone in molecular electronics scored by Berkeley Lab and Columbia University team July 29th, 2015

Industrial

Industrial Nanotech, Inc. Provides Update on PCAOB Audited Financials July 27th, 2015

Iranian Scientists Create Best Conditions for Synthesis of Gold Nanolayers July 23rd, 2015

Nanosorbents Reduce Amount of Heavy Metals in Petrochemical Wastewater July 23rd, 2015

More efficient process to produce graphene developed by Ben-Gurion University researchers July 23rd, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project