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A bioactive and biocompatible material was designed and produced by engineers from Iran Polymer and Petrochemistry Research Center by using nanoparticles with the ability to quickly treat damaged bones.
In addition to having the advantages of other bioactive materials, this material is able to speed up the proliferation and differentiation of bone cells.
Although it has been proved that hydroxyapatite particles increase in-vitro cellular proliferation and differentiation, not many studies have so far been carried out on the effect of hydroxyapatite nanoparticles stabilized on the polymeric bed of poly hydroxy alkanoate on cellular responds. It is obvious that the determination of the effect of hydroxyapatite nanoparticles on the cellular behavior of poly hydroxy alkanoate polymeric bed is the first and the most important step in order to develop the applications of such nanocomposites.
Mehdi Sadat Shojayee, one of the researchers, elaborated on the purpose of the study. "In the present study, the objective was to synthesize a bioactive and biocompatible material that is able to speed up the proliferation and differentiation of bone cells in addition to having the advantages of other bioactive materials. Therefore, they can treat bone damages more quickly."
Significant modification in biological properties of poly hydroxy alkanoate/ hydroxyapatite nanocomposites in comparison with that of the pure polymer may be one of the most important results of the research. Taking into consideration the fact that the synthesized nanocomposites have increased bioactivity and they trigger the proliferation of bone cells and the differentiation of pre-bone cells to mature bone cells at the same time, the application of these nanocomposites can increase significantly the treatment of bone in comparison with the traditional samples.
Results of the research have been published in Materials Science and Engineering C, vol. 33, issue 5, 1 July 2013. For more information about the details of the research, study the full article on pages 2776-2787 on the same journal.
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