Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > MANA Research Highlight: Smart nanofibers to treat kidney failure

The newly-fabricated nanofiber mesh for the removal of toxins from the blood, made by WPI-MANA researchers, may be incorporated into wearable blood purification systems for kidney failure patients.
The newly-fabricated nanofiber mesh for the removal of toxins from the blood, made by WPI-MANA researchers, may be incorporated into wearable blood purification systems for kidney failure patients.

Abstract:
A simple way to treat kidney failure. A new technique for purifying blood using a nanofiber mesh could prove useful as a cheap, wearable alternative to kidney dialysis.

MANA Research Highlight: Smart nanofibers to treat kidney failure

Tsukuba, Japan | Posted on March 6th, 2014

The newly-fabricated nanofiber mesh for the removal of toxins from the blood, made by WPI-MANA researchers, may be incorporated into wearable blood purification systems for kidney failure patients.

Kidney failure results in a build up of toxins and excess waste in the body. Dialysis is the most common treatment, performed daily either at home or in hospital. However, dialysis machines require electricity and careful maintenance, and are therefore more readily available in developed countries than poorer nations. Around one million people die each year worldwide from potentially preventable end-stage renal disease.

In addition to this, in the aftermath of disasters such as the Japanese earthquake and tsunami of 2011, dialysis patients are frequently left without treatment until normal hospital services are resumed. With this in mind, Mitsuhiro Ebara and co-workers at the International Center for Materials Nanoarchitectonics, National Institute for Materials Science in Ibaraki, Japan, have developed a way of removing toxins and waste from blood using a cheap, easy-to-produce nanofiber mesh1. The mesh could be incorporated into a blood purification product small enough to be worn on a patient's arm, reducing the need for expensive, time-consuming dialysis.

The team made their nanofiber mesh using two components: a blood-compatible primary matrix polymer made from polyethylene-co-vinyl alchohol, or EVOH, and several different forms of zeolites - naturally occurring aluminosilicates. Zeolites have microporous structures capable of adsorbing toxins such as creatinine from blood.

The researchers generated the mesh using a versatile and cost-effective process called electrospinning - using an electrical charge to draw fibers from a liquid. Ebara and his team found that the silicon-aluminum ratio within the zeolites is critical to creatinine adsorption. Beta type 940-HOA zeolite had the highest capacity for toxin adsorption, and shows potential for a final blood purification product.

Although the new design is still in its early stages and not yet ready for production, Ebara and his team are confident that a product based on their nanofiber mesh will soon be a feasible, compact and cheap alternative to dialysis for kidney failure patients across the world.

Reference

1. K. Namekawa, M.T. Schreiber, T. Aoyagi, & M. Ebara. Fabrication of zeolite-polymer composite nanofibers for removal of uremic toxins from kidney failure patients. Biomaterials Science (2014)

doi: 10.1039/c3bm60263j

Affiliations

The researchers on this project are associated with the following institution:

International Center for Materials Nanoarchitechtonics (WPI-MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan

####

About International Center of Materials Nanoarchitectonics (MANA)
The International Center for Materials Nanoarchitectonics (MANA) was one of the five research centers selected by Japan's Ministry of Education, Culture, Sports, Science and Technology (MEXT) for the World Premier International (WPI) Research Center Initiative in 2007. The aim of the WPI is to create new world-class research facilities sufficiently attractive to prompt outstanding researchers from around the world to want to work in them, and MANA was established under this premise to encourage proactive science and technology research with a team of excellent researchers. MANA has been called one of Japan's best research institutes not only for its research output, but also for its efforts to internationalize and establish effective programs for training young researchers.

For more information, please click here

Contacts:
International Center of Materials Nanoarchitectonics (MANA)
National Institute for Materials Science
1-1 Namiki Tsukuba, Ibaraki 305-0044 JAPAN
Phone: +81-29-860-4710
mana-pr[AT]ml.nims.go.jp
http://www.nims.go.jp/mana/

Publisher
International Center for Materials Nanoarchitectonics (WPI-MANA)
Address: 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
URL: http://www.nims.go.jp/mana/

Copyright © International Center of Materials Nanoarchitectonics (MANA)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Haydale and Goodfellow Announce Major Distribution Agreement for Functionalised Graphene Materials July 21st, 2014

Relaunch of the Nanoscribe Website New design, optimized research, and impressive gallery of applications July 21st, 2014

Dongbu HiTek Unveils Low-Voltage BCDMOS Process for Efficient Power Management in Smart Phones and Tablet Computers July 21st, 2014

Iran to Host 1st Asian Congress on Nanostructures on Kish Island July 21st, 2014

Nanomedicine

SentiMag® Now Available in Australia and New Zealand July 21st, 2014

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs July 21st, 2014

Iranian Scientists Use Nanosensors to Achieve Best Limit for Early Cancer Diagnosis July 19th, 2014

Production of Non-Virus Nanocarriers with Highest Amount of Gene Delivery July 17th, 2014

Discoveries

Oregon chemists eye improved thin films with metal substitution: Solution-based inorganic process could drive more efficient electronics and solar devices July 21st, 2014

Steam from the sun: New spongelike structure converts solar energy into steam July 21st, 2014

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs July 21st, 2014

Carbyne morphs when stretched: Rice University calculations show carbon-atom chain would go metal to semiconductor July 21st, 2014

Announcements

Oxford Instruments Asylum Research Opens an Atomic Force Microscopy Demonstration Lab in Mumbai, India July 21st, 2014

Steam from the sun: New spongelike structure converts solar energy into steam July 21st, 2014

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs July 21st, 2014

Iran to Host 1st Asian Congress on Nanostructures on Kish Island July 21st, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE