Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > New Nanoprobe Invented for Early Diagnosis of Prostate Cancer

Abstract:
Iranian researchers in association with their Australian and Belgian colleagues successfully produced a new nanoprobe to diagnose cancerous cells.

New Nanoprobe Invented for Early Diagnosis of Prostate Cancer

Tehran, Iran | Posted on January 20th, 2014

The main characteristic of the nanoprobe is to diagnosis the disease before it causes physiological changes in the body. Among the applicable properties of the results of this research in the field of medicine, mention can be made of imaging, separation of cancerous cells from healthy ones, hyperthermia, and studying the amount of gene expression.

Taking into account the advantages and wide applications of MRI in different cancer treatment stages, the need for paying attention to new imaging methods is increasing day by day to converge and improve the sensitivity of imaging method, specially magnetic resonance molecular imaging (MRMI).

In this research, a magnetic nanoprobe was designed and tested to increase the sensitivity and make more specialized MRI method to specifically detect prostate cancer cells.

In this research, PSMA antigen, which is a specific antigen for prostate cancer with high expression on the surface of cancerous cells but with no expression on the surface of prostate natural cells, was characterized and determined as an ideal target agent. Next, J591 antibody was chosen as targeting agent due to its unique properties. The antibody was attached to the magnetic iron nanoparticle with a coating of polyethylene glycol and -NH2 surfactants after activation and preparation of particles by using a specific cross linker entitled Sulfo-SMCC. Finally and after the production of the nanoprobe, its physical and chemical properties and its performance were investigated in in-vitro and in-vivo applications.

The difference in this research with the similar researches is in introducing and developing the contrast agent that is able to detect prostate cancer cells among the healthy ones, which can result in early diagnosis of the disease before it causes physiological changes on the surface of cells before changing the anatomy.

Results of the research have been published in details in Contrast Media & Molecular Imaging, vol. 8, September 2012, pp. 175-184.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Chemical cages: New technique advances synthetic biology February 10th, 2016

New thin film transistor may lead to flexible devices: Researchers engineer an electronics first, opening door to flexible electronics February 10th, 2016

Making sense of metallic glass February 9th, 2016

Electron's 1-D metallic surface state observed: A step for the prediction of electronic properties of extremely-fine metal nanowires in next-generation semiconductors February 9th, 2016

Nanomedicine

Nanoparticle therapy that uses LDL and fish oil kills liver cancer cells February 9th, 2016

Leading bugs to the death chamber: A kinder face of cholesterol February 8th, 2016

UTHealth research looks at nanotechnology to help prevent preterm birth February 7th, 2016

Scientists take key step toward custom-made nanoscale chemical factories: Berkeley Lab researchers part of team that creates new function in tiny protein shell structures February 6th, 2016

Discoveries

Chemical cages: New technique advances synthetic biology February 10th, 2016

New thin film transistor may lead to flexible devices: Researchers engineer an electronics first, opening door to flexible electronics February 10th, 2016

Making sense of metallic glass February 9th, 2016

Electron's 1-D metallic surface state observed: A step for the prediction of electronic properties of extremely-fine metal nanowires in next-generation semiconductors February 9th, 2016

Announcements

Chemical cages: New technique advances synthetic biology February 10th, 2016

New thin film transistor may lead to flexible devices: Researchers engineer an electronics first, opening door to flexible electronics February 10th, 2016

Superconductivity: Footballs with no resistance - Indications of light-induced lossless electricity transmission in fullerenes contribute to the search for superconducting materials for practical applications February 9th, 2016

SUNY Poly and GLOBALFOUNDRIES Announce New $500M R&D Program in Albany To Accelerate Next Generation Chip Technology: Arrival of Second Cutting Edge EUV Lithography Tool Launches New Patterning Center That Will Generate Over 100 New High Tech Jobs at SUNY Poly February 9th, 2016

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Chemical cages: New technique advances synthetic biology February 10th, 2016

New thin film transistor may lead to flexible devices: Researchers engineer an electronics first, opening door to flexible electronics February 10th, 2016

Making sense of metallic glass February 9th, 2016

Electron's 1-D metallic surface state observed: A step for the prediction of electronic properties of extremely-fine metal nanowires in next-generation semiconductors February 9th, 2016

Research partnerships

Chemical cages: New technique advances synthetic biology February 10th, 2016

SUNY Poly and GLOBALFOUNDRIES Announce New $500M R&D Program in Albany To Accelerate Next Generation Chip Technology: Arrival of Second Cutting Edge EUV Lithography Tool Launches New Patterning Center That Will Generate Over 100 New High Tech Jobs at SUNY Poly February 9th, 2016

Making sense of metallic glass February 9th, 2016

Nanoscale cavity strongly links quantum particles: Single photons can quickly modify individual electrons embedded in a semiconductor chip and vice versa February 8th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic