Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > New Nanoprobe Invented for Early Diagnosis of Prostate Cancer

Abstract:
Iranian researchers in association with their Australian and Belgian colleagues successfully produced a new nanoprobe to diagnose cancerous cells.

New Nanoprobe Invented for Early Diagnosis of Prostate Cancer

Tehran, Iran | Posted on January 20th, 2014

The main characteristic of the nanoprobe is to diagnosis the disease before it causes physiological changes in the body. Among the applicable properties of the results of this research in the field of medicine, mention can be made of imaging, separation of cancerous cells from healthy ones, hyperthermia, and studying the amount of gene expression.

Taking into account the advantages and wide applications of MRI in different cancer treatment stages, the need for paying attention to new imaging methods is increasing day by day to converge and improve the sensitivity of imaging method, specially magnetic resonance molecular imaging (MRMI).

In this research, a magnetic nanoprobe was designed and tested to increase the sensitivity and make more specialized MRI method to specifically detect prostate cancer cells.

In this research, PSMA antigen, which is a specific antigen for prostate cancer with high expression on the surface of cancerous cells but with no expression on the surface of prostate natural cells, was characterized and determined as an ideal target agent. Next, J591 antibody was chosen as targeting agent due to its unique properties. The antibody was attached to the magnetic iron nanoparticle with a coating of polyethylene glycol and -NH2 surfactants after activation and preparation of particles by using a specific cross linker entitled Sulfo-SMCC. Finally and after the production of the nanoprobe, its physical and chemical properties and its performance were investigated in in-vitro and in-vivo applications.

The difference in this research with the similar researches is in introducing and developing the contrast agent that is able to detect prostate cancer cells among the healthy ones, which can result in early diagnosis of the disease before it causes physiological changes on the surface of cells before changing the anatomy.

Results of the research have been published in details in Contrast Media & Molecular Imaging, vol. 8, September 2012, pp. 175-184.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Quantum memory with record-breaking capacity based on laser-cooled atoms December 15th, 2017

Record high photoconductivity for new metal-organic framework material December 15th, 2017

Error-free into the quantum computer age December 15th, 2017

Leti Will Demonstrate First 3D Anti-Crash Solution for Embedding in Drones: Fitted on a Mass-Market Microcontroller, 360Fusion Software Technology Detects any Dynamic Obstacle and Helps Guide Drones Away from Collisions December 15th, 2017

Nanomedicine

Synthetic protein packages its own genetic material and evolves computationally designed protein assemblies are advancing research in synthetic life and in targeted drug delivery December 15th, 2017

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Discoveries

Quantum memory with record-breaking capacity based on laser-cooled atoms December 15th, 2017

Record high photoconductivity for new metal-organic framework material December 15th, 2017

Error-free into the quantum computer age December 15th, 2017

Synthetic protein packages its own genetic material and evolves computationally designed protein assemblies are advancing research in synthetic life and in targeted drug delivery December 15th, 2017

Announcements

Quantum memory with record-breaking capacity based on laser-cooled atoms December 15th, 2017

Record high photoconductivity for new metal-organic framework material December 15th, 2017

Error-free into the quantum computer age December 15th, 2017

Leti Will Demonstrate First 3D Anti-Crash Solution for Embedding in Drones: Fitted on a Mass-Market Microcontroller, 360Fusion Software Technology Detects any Dynamic Obstacle and Helps Guide Drones Away from Collisions December 15th, 2017

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Quantum memory with record-breaking capacity based on laser-cooled atoms December 15th, 2017

Record high photoconductivity for new metal-organic framework material December 15th, 2017

Error-free into the quantum computer age December 15th, 2017

Synthetic protein packages its own genetic material and evolves computationally designed protein assemblies are advancing research in synthetic life and in targeted drug delivery December 15th, 2017

Research partnerships

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Wheat gets boost from purified nanotubes: Rice University toxicity study shows plant growth enhanced by -- but only by -- purified nanotubes December 6th, 2017

Copper will replace toxic palladium and expensive platinum in the synthesis of medications: The effectiveness of copper nanoparticles as a catalyst has been proven December 5th, 2017

Researchers advance technique to detect ovarian cancer: Rice, MD Anderson use fluorescent carbon nanotube probes to achieve first in vivo success November 30th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project