Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > A nanofibrous conduit suitable for repair of long-segment sciatic nerve defects

Abstract:
Autografts or allografts are commonly used in neurosurgery. Unfortunately, autografts have limitations such as body injury, repeated surgeries and disproportion of grafted nerve tissue in terms of size and structure. In addition, a similar problem, i.e., stimulation of the immune system, will be encountered in transplantation of allografts or xenografts. Some studies used artificial nerve conduits to repair nerve defects. Among the artificial nerve conduits used, nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) conduits exhibit several advantages. One advantage of these nerve conduits is that they can be bent to an angle of up to 180˚ and then restore to their original shape, which is necessary for adaptation inside a living system. Moreover, the PHBV conduits have a thin wall and a highly porous structure, which are important determinants for nutrient transport into the conduit. A further advantage is that they can be easily fabricated and rolled to any required length and diameter by heat processing. Dr. Esmaeil Biazar and team from Islamic Azad University, Tonekabon, Iran used nanofibrous PHBV conduit and autologous sciatic nerve to bridge 30-mm-long rat sciatic nerve gaps. Within 4 months after surgery, rat sciatic nerve functional recovery was evaluated per month by behavioral analyses. Results showed that rat sciatic nerve functional recovery was similar after nanofibrous PHBV conduit and autologous nerve grafting. These findings, published in the Neural Regeneration Research (Vol. 8, No. 27, 2013), suggest that nanofibrous PHBV conduit is suitable in use for repair of long-segment sciatic nerve defects.

A nanofibrous conduit suitable for repair of long-segment sciatic nerve defects

Shenyang, PR China | Posted on October 28th, 2013

Article: " Efficacy of nanofibrous conduits in repair of long- segment sciatic nerve defects," by Esmaeil Biazar1, Saeed Heidari Keshel2, 3, Majid Pouya4 (1 Department of Biomaterial Engineering, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran; 2 Student Research Committee, Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 3 Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran; 4 Faculty of Medical Sciences, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran)

Biazar E, Heidari SK, Pouya M. Efficacy of nanofibrous conduits in repair of long-segment sciatic nerve defects. Neural Regen Res. 2013;8(27):2501-2509.

####

For more information, please click here

Contacts:
Meng Zhao

86-138-049-98773
Neural Regeneration Research

Copyright © Neural Regeneration Research

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Full text:

Related News Press

News and information

Wear-resistant ceramic powder maximises component lifespan in high-stress applications: Innovnano’s nanostructured 3YSZ offers improved tribological performance for manufacturing components September 18th, 2014

IEEE International Electron Devices Meeting To Celebrate 60th Anniversary as The Leading Technical Conference for Advanced Semiconductor Devices September 18th, 2014

FEI Opens New Technology Center in Czech Republic: FEI expands its presence in Brno with the opening of a new, larger facility September 18th, 2014

Biosensors Get a Boost from Graphene Partnership: $5 Million Investment Supports Dozens of Jobs and Development of 300mm Fabrication Process and Wafer Transfer Facility September 18th, 2014

Nanomedicine

The Pocket Project will develop a low-cost and accurate point-of-care test to diagnose Tuberculosis: ICN2 holds a follow-up meeting of the Project on September 18th - 19th September 18th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Nanoscience makes your wine better September 17th, 2014

Discoveries

The Pocket Project will develop a low-cost and accurate point-of-care test to diagnose Tuberculosis: ICN2 holds a follow-up meeting of the Project on September 18th - 19th September 18th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Toward making lithium-sulfur batteries a commercial reality for a bigger energy punch September 17th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Announcements

Wear-resistant ceramic powder maximises component lifespan in high-stress applications: Innovnano’s nanostructured 3YSZ offers improved tribological performance for manufacturing components September 18th, 2014

IEEE International Electron Devices Meeting To Celebrate 60th Anniversary as The Leading Technical Conference for Advanced Semiconductor Devices September 18th, 2014

FEI Opens New Technology Center in Czech Republic: FEI expands its presence in Brno with the opening of a new, larger facility September 18th, 2014

Biosensors Get a Boost from Graphene Partnership: $5 Million Investment Supports Dozens of Jobs and Development of 300mm Fabrication Process and Wafer Transfer Facility September 18th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

Scientists refine formula for nanotube types: Rice University theorists determine factors that give tubes their chiral angles September 17th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Toward making lithium-sulfur batteries a commercial reality for a bigger energy punch September 17th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Research partnerships

Biosensors Get a Boost from Graphene Partnership: $5 Million Investment Supports Dozens of Jobs and Development of 300mm Fabrication Process and Wafer Transfer Facility September 18th, 2014

The Pocket Project will develop a low-cost and accurate point-of-care test to diagnose Tuberculosis: ICN2 holds a follow-up meeting of the Project on September 18th - 19th September 18th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Carbon Sciences Developing Breakthrough Technology to Mass-Produce Graphene -- the New Miracle Material: Company Enters Into an Agreement With the University of California, Santa Barbara (UCSB) to Fund the Further Development of a New Graphene Process September 16th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE