Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > How cells get a skeleton: Stress generated by nano-motors within animal cells can lead to the creation of a condensed layer of filaments beneath the outer cell membrane

Abstract:
The mechanism responsible for generating part of the skeletal support for the membrane in animal cells is not yet clearly understood. Now, Jean-François Joanny from the Physico Chemistry Curie Unit at the Curie Institute in Paris and colleagues have found that a well-defined layer beneath the cell outer membrane forms beyond a certain critical level of stress generated by motor proteins within the cellular system. These findings, which offer a new understanding of the formation of this so-called cortical layer, have just been published in EPJ E.

How cells get a skeleton: Stress generated by nano-motors within animal cells can lead to the creation of a condensed layer of filaments beneath the outer cell membrane

Heidelberg, Germany | Posted on June 11th, 2013

Active gels are ideal for modelling the similar material found in living cells' structure, made of a dynamic, filamentous scaffold. They are composed of components that take up energy and do directed work. Indeed, chemical energy is fed into the cells' constituents and is transformed into mechanical work through the assembly of its internal filaments, made of a polymer called actin, and a protein that functions as a tiny motor, called myosin. Both provide the active gel-like substance found in cells with a spontaneous tendency to contract. As a result, the cells can either maintain or change their shape, or even adhere, spread, divide and crawl.

In this study, the authors have created hydrodynamic models of active gels to model the cell cortex, whereby the active gel is polymerising at the surface and depolymerising throughout the gel as a whole. They first derived the equations providing a coarse-grained description of cortical dynamics, then calculated the configuration in which their model was in a steady state..

They found that for sufficiently high levels of contractile stress it consisted of a dense layer near the membrane, which abruptly cut off beyond a certain thickness. The key advance in their model is the inclusion of gel disassembly throughout the system, and the contractility due to molecular motors.

Full bibliographic information

Reference
J.-F. Joanny et al. (2013), The actin cortex as an active wetting layer, European Physical Journal E. DOI 10.1140/epje/i2013-13052-9

####

About Springer Science+Business Media
Springer Science+Business Media (www.springer.com) is a leading global scientific publisher, providing researchers in academia, scientific institutions and corporate R&D departments with quality content via innovative information products and services. Springer is also a trusted local-language publisher in Europe – especially in Germany and the Netherlands – primarily for physicians and professionals working in the automotive, transport and healthcare sectors. Roughly 2,000 journals and more than 7,000 new books are published by Springer each year, and the group is home to the world’s largest STM eBook collection, as well as the most comprehensive portfolio of open access journals. Springer employs nearly 6,200 individuals across the globe and in 2011 generated sales of approximately EUR 875 million.

For more information, please click here

Contacts:
Sophia Grein
tel. +49 6221 4878414


Joan Robinson
+49-6221-487-8130

Copyright © AlphaGalileo

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Pioneering Southampton scientist awarded prestigious physics medal July 3rd, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Discovery of nanotubes offers new clues about cell-to-cell communication July 2nd, 2015

Nanomedicine

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Iranian Scientists Find Simple, Economic Method to Synthesize Antibacterial Nanoparticles July 2nd, 2015

Leti Announces Launch of First European Nanomedicine Characterisation Laboratory: Project Combines Expertise of 9 Partners in 8 Countries to Foster Nanomedicine Innovation and Facilitate Regulatory Approval July 1st, 2015

Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cells June 30th, 2015

Discoveries

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Producing spin-entangled electrons July 2nd, 2015

NIST Group Maps Distribution of Carbon Nanotubes in Composite Materials July 2nd, 2015

Announcements

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Pioneering Southampton scientist awarded prestigious physics medal July 3rd, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

NIST Group Maps Distribution of Carbon Nanotubes in Composite Materials July 2nd, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Pioneering Southampton scientist awarded prestigious physics medal July 3rd, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

NIST Group Maps Distribution of Carbon Nanotubes in Composite Materials July 2nd, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project