Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Artificial atoms allow for magnetic resonance on individual cells: Scientists at ICFO develop a technique for MRIs on a molecular scale

This image illustrates the nanomanipulation of an artificial atom.

Credit: ICFO
This image illustrates the nanomanipulation of an artificial atom.

Credit: ICFO

Abstract:
Researchers from the Institute of Photonic Sciences (ICFO), in collaboration with the CSIC and Macquarie University in Australia, have developed a new technique, similar to the MRI but with a much higher resolution and sensitivity, which has the ability to scan individual cells. In an article published in Nature Nanotech, and highlighted by Nature, ICFO Prof. Romain Quidant explains how this was accomplished using artificial atoms, diamond nanoparticles doped with nitrogen impurity, to probe very weak magnetic fields such as those generated in some biological molecules.

Artificial atoms allow for magnetic resonance on individual cells: Scientists at ICFO develop a technique for MRIs on a molecular scale

Barcelona, Spain | Posted on February 11th, 2013

The conventional MRI registers the magnetic fields of atomic nuclei in our bodies which have been previously excited by an external electromagnetic field. The collective response of all of these atoms makes it possible to diagnose and monitor the evolution of certain diseases. However, this conventional technique has a diagnostic resolution on a millimetric scale. Smaller objects do not give enough signal to be measured.

The innovative technique proposed by the group led by Dr. Quidant significantly improves the resolution at the nanometer scale (nearly one million times smaller than the millimeter), making it possible to measure very weak magnetic fields, such as those created by proteins. "Our approach opens the door for the performance of magnetic resonances on isolated cells which will offer new sources of information and allow us to better understand the intracellular processes, enabling noninvasive diagnosis," explains Michael Geiselmann, ICFO researcher who conducted the experiment. Until now, it has only been possible to reach this resolution in the laboratory, using individual atoms at temperatures close to the absolute zero (approx. -273 degrees Celsius.)

Individual atoms are structures that are highly sensitive to their environment, with a great ability to detect nearby electromagnetic fields. The challenge these atoms present is that they are so small and volatile that in order to be manipulated, they must be cooled to temperatures near the absolute zero. This complex process requires an environment that is so restrictive that it makes individual atoms unviable for potential medical applications. Artificial atoms used by Quidant and his team are formed by a nitrogen impurity captured within a small diamond crystal. "This impurity has the same sensitivity as an individual atom but is very stable at room temperature due to its encapsulation. This diamond shell allows us to handle the nitrogen impurity in a biological environment and, therefore, enables us to scan cells" argues Dr. Quidant.

To trap and manipulate these artificial atoms, researchers use laser light. The laser works like tweezers, leading the atoms above the surface of the object to study and extract information from its tiny magnetic fields.

The emergence of this new technique could revolutionize the field of medical imaging, allowing for substantially higher sensitivity in clinical analysis, an improved capacity for early detection of diseases, and thus a higher probability for successful treatment.

This research has been possible thanks to the support of the private foundation Cellex Barcelona.

####

About ICFO-The Institute of Photonic Sciences
ICFO-The Institute of Photonic Sciences was created in 2002 by the government of Catalonia and the Technical University of Catalonia. ICFO is a center of research excellence devoted to the sciences and technologies of light with a triple mission: to conduct frontier research, train the next generation of scientists and technologists, and provide knowledge and technology transfer. As part of ICFO's goal to usher advances "made at ICFO" into society, the institute actively promotes the creation of spin-off companies by ICFO researchers.

Research at ICFO targets the forefront of science and technology based on light with programs directed at applications in Health, Renewable Energies, Information Technologies, Security and Industrial processes, among others. The center currently hosts more than 250 researchers and PhD students working in more than 60 different laboratories. All research groups and facilities are located in a dedicated 14.000 m2 building situated in the Mediterranean Technology Park in the metropolitan area of Barcelona.

ICFO researchers publish in the most prestigious journals and collaborate with a wide range of companies around the world. In recognition of research excellence, ICFO has been awarded the elite Severo Ochoa distinction by the Government of Spain. Foundation Cellex finances the NEST program at ICFO which makes possible many ambitious frontier research projects

For more information, please click here

Contacts:
Albert Mundet

34-935-542-246

Copyright © ICFO-The Institute of Photonic Sciences

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists create antilaser for ultracold atoms condensate August 16th, 2018

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

Particles pull last drops of oil from well water: Rice University engineers find nanoscale solution to 'produced water' problem August 15th, 2018

CTI Materials drives nano commercialization with it's patented surfactant free nanoparticle dispersions August 15th, 2018

Imaging

New technology can detect hundreds of proteins in a single sample: Improvement of barcoding technique offers cost-effective alternative to current technology August 13th, 2018

Feds back Rice U. study of nanoscale electrocatalysis: Professors Christy Landes, Stephan Link will analyze mechanisms to improve chemical reactions July 25th, 2018

Researchers use nanotechnology to improve the accuracy of measuring devices July 24th, 2018

Oxford Instruments’ 22 Tesla superconducting magnet system commissioned at the UAM, making it the most intense magnetic field available outside a large international facility July 12th, 2018

Nanomedicine

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

New technology can detect hundreds of proteins in a single sample: Improvement of barcoding technique offers cost-effective alternative to current technology August 13th, 2018

Scientists squeeze nanocrystals in a liquid droplet into a solid-like state and back again: Simple chemical technique transforms crystal mixture where 2 liquids meet August 9th, 2018

Nanoscience and the future of healthcare kick off first day of ACS national meeting in Boston: Presidential events highlight safety, diversity and groundbreaking research August 2nd, 2018

Discoveries

Scientists create antilaser for ultracold atoms condensate August 16th, 2018

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

Particles pull last drops of oil from well water: Rice University engineers find nanoscale solution to 'produced water' problem August 15th, 2018

How hot is Schrödinger's coffee? August 15th, 2018

Announcements

Scientists create antilaser for ultracold atoms condensate August 16th, 2018

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

Particles pull last drops of oil from well water: Rice University engineers find nanoscale solution to 'produced water' problem August 15th, 2018

How hot is Schrödinger's coffee? August 15th, 2018

Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

Particles pull last drops of oil from well water: Rice University engineers find nanoscale solution to 'produced water' problem August 15th, 2018

Breaking down the Wiedemann-Franz law: In a study exploring the coupling between heat and particle currents in a gas of strongly interacting atoms, physicists at ETH Zurich find puzzling behaviours August 10th, 2018

Yale-NUS scientist and collaborators solve open theoretical problem on electron interactions August 10th, 2018

Nanobiotechnology

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

New technology can detect hundreds of proteins in a single sample: Improvement of barcoding technique offers cost-effective alternative to current technology August 13th, 2018

Scientists squeeze nanocrystals in a liquid droplet into a solid-like state and back again: Simple chemical technique transforms crystal mixture where 2 liquids meet August 9th, 2018

Nanoscience and the future of healthcare kick off first day of ACS national meeting in Boston: Presidential events highlight safety, diversity and groundbreaking research August 2nd, 2018

Photonics/Optics/Lasers

Scientists create antilaser for ultracold atoms condensate August 16th, 2018

Breaking down the Wiedemann-Franz law: In a study exploring the coupling between heat and particle currents in a gas of strongly interacting atoms, physicists at ETH Zurich find puzzling behaviours August 10th, 2018

Optical fibers that can 'feel' the materials around them August 7th, 2018

NUST MISIS scientists present metamaterial for solar cells and nanooptics July 23rd, 2018

Research partnerships

Breaking down the Wiedemann-Franz law: In a study exploring the coupling between heat and particle currents in a gas of strongly interacting atoms, physicists at ETH Zurich find puzzling behaviours August 10th, 2018

Yale-NUS scientist and collaborators solve open theoretical problem on electron interactions August 10th, 2018

Scientists squeeze nanocrystals in a liquid droplet into a solid-like state and back again: Simple chemical technique transforms crystal mixture where 2 liquids meet August 9th, 2018

Quantum chains in graphene nanoribbons: Breakthrough in nanoresearch August 9th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project