Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > OICR and MaRS Innovation announce funding for the development of Cellax™, a nanotechnology-based cancer drug

Abstract:
The Ontario Institute for Cancer Research (OICR) and MaRS Innovation (MI) today announced $1.5 million in funding from OICR over three years to further develop Cellax™, a nanoparticle drug that could offer an alternative to chemotherapy with fewer side effects.

OICR and MaRS Innovation announce funding for the development of Cellax™, a nanotechnology-based cancer drug

Toronto, Canada | Posted on November 14th, 2012

"Cellax is promising because it provides a more targeted strategy for treating tumours, killing tumour cells while minimizing the effect on healthy tissue," said Dr. Rima Al-awar, Director, OICR's Medicinal Chemistry Platform. "OICR is proud to invest in a technology that has such potential to one day improve quality of life for cancer patients."

Cellax, invented by Dr. Shyh-Dar Li and his research team in OICR's Medicinal Chemistry Platform group, is a drug-polymer conjugate based on Dr. Li's proprietary NanoCMC™ technology. These polymers self-assemble into defined nanoparticles and, when injected, selectively accumulate in tumours. Because of this property, the drug is released where it is most needed, increasing therapeutic benefits and reducing the side effects associated with conventional chemotherapy.

With the new funding, the Cellax team will conduct the pre-clinical manufacturing and toxicology studies necessary to bring Cellax to a clinical trial in cancer patients.

"Tumours are by nature more permeable to nano-sized molecules than normal tissue," says Li. "We are developing Cellax to exploit this weakness. We hope to use the NanoCMC platform to deliver drugs that will build up only in tumours. This would spare patients the side effects associated with less targeted treatments, which damage healthy cells as well as tumours."

Cellax, which is made from biocompatible components, is stable in storage and outperforms conventional chemotherapy in pre-clinical models of human tumours.

OICR is supporting the Cellax project through its Intellectual Property Development and Commercialization (IPDC) Fund, which was established to bridge the gap in the commercialization process between public funding agencies and private investors. All IPDC candidate projects are rigorously reviewed by external subject-specific experts in business and technology.

"MaRS Innovation provided the Cellax project with early-stage funding along with business development and management through our high-touch, embedded model," said Dr. Raphael Hofstein, president and CEO of MaRS Innovation. "MI continues to lead Cellax's commercialization strategy. We believe Cellax meets a clear clinical need within the multibillion-dollar Taxane market, and we anticipate that Cellax will emerge as a significant new player."

####

About Ontario Institute for Cancer Research
OICR is an innovative cancer research and development institute dedicated to prevention, early detection, diagnosis and treatment of cancer. The Institute is an independent, not-for-profit corporation, supported by the Government of Ontario. The annual budget for OICR, its research partners and collaborators exceeds $150 million. This supports more than 1,600 investigators, clinician scientists, research staff and trainees located at its headquarters and in research institutes and academia across the Province of Ontario. It has research hubs in Hamilton, Kingston, London, Ottawa, Thunder Bay and Toronto. OICR has key research efforts underway in small molecules, biologics, stem cells, imaging, genomics, informatics and bio-computing. For more information, please visit the website at www.oicr.on.ca

About MaRS Innovation

MaRS Innovation (MI) is the commercialization agent for the exceptional discovery pipeline from 16 leading Ontario academic institutions. As a single-entry point to total member research activity of $1 billion in annual research and development, MI provides an easy gateway for investors and licensees who wish to access technology assets in Ontario. Supported by the Government of Canada through the Networks of Centres of Excellence, by the Government of Ontario through the Ontario Centres of Excellence, and by its member institutions, MI is a transformational partnership that turns research strengths into real commercial opportunities. MI's portfolio includes the most promising assets and advances commercialization into global markets through industry partnerships, licensing and company creation.

For more information, please click here

Contacts:
Ontario Institute for Cancer Research
Contact: Christopher Needles
Manager, Editorial Services and Media Relations

Telephone: 416-673-8505
Mobile: 416-319-5252
Twitter @OICR_news

MaRS Innovation
Elizabeth Monier-Williams
Marketing and Communications Manager

Telephone: 647-260-7850
Mobile: 647-537-9097
Twitter @MaRSInnovation

Copyright © CNW Group Ltd.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Solar-to-fuel system recycles CO2 to make ethanol and ethylene: Berkeley Lab advance is first demonstration of efficient, light-powered production of fuel via artificial photosynthesis September 19th, 2017

A new approach to ultrafast light pulses: Unusual fluorescent materials could be used for rapid light-based communications systems September 19th, 2017

New quantum phenomena in graphene superlattices September 18th, 2017

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

Govt.-Legislation/Regulation/Funding/Policy

Solar-to-fuel system recycles CO2 to make ethanol and ethylene: Berkeley Lab advance is first demonstration of efficient, light-powered production of fuel via artificial photosynthesis September 19th, 2017

New insights into nanocrystal growth in liquid: Understanding process that creates complex crystals important for energy applications September 14th, 2017

Magnetic cellular 'Legos' for the regenerative medicine of the future September 12th, 2017

First on-chip nanoscale optical quantum memory developed: Smallest-yet optical quantum memory device is a storage medium for optical quantum networks with the potential to be scaled up for commercial use September 11th, 2017

Nanomedicine

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

Arrowhead Hosts Investor & Analyst R&D Day to Introduce TRiM(TM) Platform and Lead RNAi-based Drug Candidates September 14th, 2017

Graphene based terahertz absorbers: Printable graphene inks enable ultrafast lasers in the terahertz range September 13th, 2017

Applications for the nanomedTAB are open until September 18th, 2017 September 13th, 2017

Announcements

Solar-to-fuel system recycles CO2 to make ethanol and ethylene: Berkeley Lab advance is first demonstration of efficient, light-powered production of fuel via artificial photosynthesis September 19th, 2017

A new approach to ultrafast light pulses: Unusual fluorescent materials could be used for rapid light-based communications systems September 19th, 2017

New quantum phenomena in graphene superlattices September 18th, 2017

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records

Magnetic cellular 'Legos' for the regenerative medicine of the future September 12th, 2017

Quantum detectives in the hunt for the world's first quantum computer September 8th, 2017

New results reveal high tunability of 2-D material: Berkeley Lab-led team also provides most precise band gap measurement yet for hotly studied monolayer moly sulfide August 26th, 2017

A more complete picture of the nano world August 24th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project