Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Immunomodulatory effect of nanoparticles

Abstract:
Polymeric nanoparticles for immunotherapy represent a dynamic research field. The possibility to control their size, charge, and other surface properties provides the opportunity to affect both uptake by immune cells and induction of immunity. Dendritic cells (DC), which represent the most potent antigen-presenting cells of the immune system, are one of the main targets of current NP-based immunotherapeutic approaches against tumors.

Immunomodulatory effect of nanoparticles

Mainz, Germany | Posted on October 25th, 2012

Researcher from the Max Planck Institute for Polymer Research in Mainz, Germany, now study the uptake of unfunctionalized, sulfonate- and phosphonate-functionalized polystyrene NP by immature DC (iDC) and mature DC (mDC). iDC display a higher time- and dose-dependent uptake of functionalized polystyrene NP mDC. Notably, NP induce an enhanced maturation of iDC resulting in a significantly enhanced T cell stimulatory capacity.

Considering the increasing use of nanomaterials in clinical studies, investigations on the effect of nanomaterials on cell morphology and functionality are critical for screening materials that can potentially be used in clinical settings. The results are important for the research on immunomodulatory properties of NP and their potential applications in immunotherapy.

####

For more information, please click here

Copyright © Wiley-VCH Materials Science Journals

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Link to the original paper on Wiley Online Library:

Related News Press

News and information

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

Nanolab Technologies LEAPS Forward with High-Performance Analysis Services to the World: Nanolab Orders Advanced Local Electrode Atom Probe (LEAP®) Microscope from CAMECA Unit of AMETEK Materials Analysis Division August 27th, 2015

Nanomedicine

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

A new technique to make drugs more soluble August 28th, 2015

These microscopic fish are 3-D-printed to do more than swim: Researchers demonstrate a novel method to build microscopic robots with complex shapes and functionalities August 26th, 2015

Glitter from silver lights up Alzheimer's dark secrets August 25th, 2015

Discoveries

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

CWRU researchers efficiently charge a lithium-ion battery with solar cell: Coupling with perovskite solar cell holds potential for cleaner cars and more August 27th, 2015

Successful boron-doping of graphene nanoribbon August 27th, 2015

Announcements

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

Nanolab Technologies LEAPS Forward with High-Performance Analysis Services to the World: Nanolab Orders Advanced Local Electrode Atom Probe (LEAP®) Microscope from CAMECA Unit of AMETEK Materials Analysis Division August 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic