Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Trojan Horse Causes Nanoparticle Allergy

Abstract:
Workers with existing allergic conditions have worse reactions when exposed to nanoparticles in the workplace, suggest Chinese scientists. They believe that the response is caused by a Trojan horse known as an exosome, which is present in all of us.

Trojan Horse Causes Nanoparticle Allergy

Germany | Posted on December 18th, 2011

Nanoparticles are becoming ubiquitous in industry and commercial applications, and there are rightly concerns about their safety, which is often still not as well understood as their physical properties. In particular, it is important for employers to understand the effects of nanoparticles on the immune system and allergic reactions to them in order to safeguard their workers against long-term and short-term effects of exposure.

Now, a team of scientists at the Chinese Academy of Sciences, Beijing, led by Guangjun Nie and Yuliang Zhao, has studied these effects using magnetic iron oxide nanoparticles. They propose that, when inhaled, the nanoparticles induce formation of a vesiclelike intra- and intercellular vehicle called an exosome in the lungs. Inhalation is the most common way for nanoparticles to be introduced to the human body. Exosomes are known to act as Trojan horses to deliver sometimes unwanted particles such as viruses into cells, and in this case they quickly remove the nanoparticles from the lungs and convey signals throughout the body, including to the immune system. In those individuals that already have some kind of allergic respiratory condition (known as sensitized individuals), these signals can result in both direct and indirect activation of T cells, which cause familiar allergic responses such as inflammation. In unsensitized individuals the body's response is much lower, as the pathway to T-cell activation only takes the indirect pathway.

The scientists believe that their work should urgently inform policy guidelines and further research to protect both sensitized and unsensitized workers from allergic reactions caused by occupational exposure to nanoparticles.

####

For more information, please click here

Copyright © John Wiley & Sons, Inc.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

M. Zhu et al., Small ; DOI: 10.1002/smll.201101708

Related News Press

News and information

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

Tokyo Institute of Technology research: Antiaromatic molecule displays record electrical conductance July 19th, 2017

Harnessing light to drive chemical reactions July 19th, 2017

Nanoparticles could spur better LEDs, invisibility cloaks July 19th, 2017

Discoveries

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

Here's a tip: Indented cement shows unique properties: Rice University models reveal nanoindentation can benefit crystals in concrete July 20th, 2017

Tokyo Institute of Technology research: Antiaromatic molecule displays record electrical conductance July 19th, 2017

Harnessing light to drive chemical reactions July 19th, 2017

Announcements

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

Here's a tip: Indented cement shows unique properties: Rice University models reveal nanoindentation can benefit crystals in concrete July 20th, 2017

Tokyo Institute of Technology research: Antiaromatic molecule displays record electrical conductance July 19th, 2017

Harnessing light to drive chemical reactions July 19th, 2017

Safety-Nanoparticles/Risk management

Tests show no nanotubes released during utilisation of nanoaugmented materials June 9th, 2017

NanoMONITOR shares its latest developments concerning the NanoMONITOR Software and the Monitoring stations April 21st, 2017

NIST updates 'sweet' 1950s separation method to clean nanoparticles from organisms January 27th, 2017

Nanoparticle exposure can awaken dormant viruses in the lungs January 17th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project