Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Trojan Horse Causes Nanoparticle Allergy

Abstract:
Workers with existing allergic conditions have worse reactions when exposed to nanoparticles in the workplace, suggest Chinese scientists. They believe that the response is caused by a Trojan horse known as an exosome, which is present in all of us.

Trojan Horse Causes Nanoparticle Allergy

Germany | Posted on December 18th, 2011

Nanoparticles are becoming ubiquitous in industry and commercial applications, and there are rightly concerns about their safety, which is often still not as well understood as their physical properties. In particular, it is important for employers to understand the effects of nanoparticles on the immune system and allergic reactions to them in order to safeguard their workers against long-term and short-term effects of exposure.

Now, a team of scientists at the Chinese Academy of Sciences, Beijing, led by Guangjun Nie and Yuliang Zhao, has studied these effects using magnetic iron oxide nanoparticles. They propose that, when inhaled, the nanoparticles induce formation of a vesiclelike intra- and intercellular vehicle called an exosome in the lungs. Inhalation is the most common way for nanoparticles to be introduced to the human body. Exosomes are known to act as Trojan horses to deliver sometimes unwanted particles such as viruses into cells, and in this case they quickly remove the nanoparticles from the lungs and convey signals throughout the body, including to the immune system. In those individuals that already have some kind of allergic respiratory condition (known as sensitized individuals), these signals can result in both direct and indirect activation of T cells, which cause familiar allergic responses such as inflammation. In unsensitized individuals the body's response is much lower, as the pathway to T-cell activation only takes the indirect pathway.

The scientists believe that their work should urgently inform policy guidelines and further research to protect both sensitized and unsensitized workers from allergic reactions caused by occupational exposure to nanoparticles.

####

For more information, please click here

Copyright © John Wiley & Sons, Inc.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

M. Zhu et al., Small ; DOI: 10.1002/smll.201101708

Related News Press

News and information

Nanostructures Increase Corrosion Resistance in Metallic Body Implants May 24th, 2015

Iranian Scientists Use Magnetic Field to Transfer Anticancer Drug to Tumor Tissue May 24th, 2015

Basel physicists develop efficient method of signal transmission from nanocomponents May 23rd, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Discoveries

Nanostructures Increase Corrosion Resistance in Metallic Body Implants May 24th, 2015

Iranian Scientists Use Magnetic Field to Transfer Anticancer Drug to Tumor Tissue May 24th, 2015

Basel physicists develop efficient method of signal transmission from nanocomponents May 23rd, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Announcements

Nanostructures Increase Corrosion Resistance in Metallic Body Implants May 24th, 2015

Iranian Scientists Use Magnetic Field to Transfer Anticancer Drug to Tumor Tissue May 24th, 2015

Basel physicists develop efficient method of signal transmission from nanocomponents May 23rd, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Safety-Nanoparticles/Risk management

Statement by QD Vision regarding European Parliamentís Vote on Cadmium-Based Quantum Dots May 20th, 2015

SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium: May 20th, 2015

Cotton fibres instead of carbon nanotubes May 9th, 2015

Nanoparticles in consumer products can significantly alter normal gut microbiome May 4th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project