Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Fighting Parkinson's with carbon nanoparticles

Abstract:
One of the problems affecting the human nervous system is dopamine deficiency. But testing of dopamine concentration is costly and requires sophisticated equipment not available in a doctor's office. Enter a team of Polish scientists who developed a method enabling the detection of dopamine in solutions both easily and cheaply, even in the presence of interferences. The study is an outcome of the NOBLESSE ('Nanotechnology, biomaterials and alternative energy source for the European Research Area (ERA))' project, which is backed with EUR 3.3 million under the 'Regions of Knowledge' Theme of the EU's Seventh Framework Programme (FP7). The results are published in the journal Biosensors and Bioelectronics.

Fighting Parkinson's with carbon nanoparticles

Warsaw, Poland | Posted on November 28th, 2011

Scientists at the Institute of Physical Chemistry of the Polish Academy of Sciences (IPC PAS) in Warsaw coated new electrodes with carbon nanoparticles deposited on silicate submicroparticles to get the targeted result. They applied the electrodes so as to determine dopamine concentration in solutions in the presence of uric and ascorbic acids, and paracetamol, substances that get in the way of dopamine analysis.

This latest development to detect dopamine could clear the path for securing fast and inexpensive medical tests that doctors can use even in their offices. This information will help physicians determine the likelihood of a patient suffering from popular nervous system disorders including Parkinson's disease.

The researchers developed the electrodes by alternating layers of silicate submicroparticles and carbon nanoparticles. According to the team, the size of the silicate submicroparticles ranges from 100 nanometres to 300 nanometres (billionth parts of a metre). Being nonconductive, they are used only as a framework extending the electrode surface. Carbon nanoparticles, ranging between 8 nanometres and 18 nanometres in size, densely coat the silicate particles that form the actual conductive working surface.

'Carbon nanoparticles have negatively charged functional groups, and the silicates positively charged ones,' explains doctoral student Anna Celebanska of the IPC PAS. 'The electrostatic interactions between them are quite strong. We checked that by multiple repeating of the immersion, a "sandwich" consisting of up to 24 layers can be obtained on the electrode surface.'

The scientists applied the new electrodes for dopamine sensing in solutions. The carbon nanoparticle-coated electrodes are placed inside a prepared solution containing the same, and the electric potential is then applied. They say dopamine is electrochemically active and can be oxidised by adjusting the potential value.

'The results of the completed tests turned out very good,' Ms Celebanska says. 'Our method is among the most sensitive methods for dopamine sensing. It allows to detect dopamine at concentrations as low as 10-7 mole per litre in the presence of interferences at concentrations up to 10-3 mole per litre.'

Commenting on the results of the study, Professor Marcin Opallo [z1]says: 'The method has a natural detection threshold, and that's why we can conclude on dopamine deficiency in the body. How large is the actual deficiency? At present we cannot answer the question. We hope, however, for further increase in the method's sensitivity.'

####

For more information, please click here

Copyright © Cordis

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Institute of Physical Chemistry of the Polish Academy of Sciences (IPC PAS):

Biosensors and Bioelectronics:

Related News Press

News and information

Silicene Labs Announces the Launch of Patent-Pending, 2D Materials Composite Index™ : The Initial 2D Materials Composite Index™ for Q2 2014 Is: 857.3; Founders Include World-Renowned Physicist and Seasoned Business and IP Professionals July 24th, 2014

Iranian Scientists Produce Transparent Nanocomposite Coatings with Longer Lifetime July 24th, 2014

Deadline Announced for Registration in 7th Int'l Nanotechnology Festival in Iran July 23rd, 2014

A Crystal Wedding in the Nanocosmos July 23rd, 2014

Nanomedicine

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

SentiMag® Now Available in Australia and New Zealand July 21st, 2014

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs July 21st, 2014

Discoveries

Iranian Scientists Produce Transparent Nanocomposite Coatings with Longer Lifetime July 24th, 2014

UCF Nanotech Spinout Developing Revolutionary Battery Technology: Power the Next Generation of Electronics with Carbon July 23rd, 2014

A Crystal Wedding in the Nanocosmos July 23rd, 2014

Nano-sized Chip "Sniffs Out" Explosives Far Better than Trained Dogs: TAU researcher's groundbreaking sensor detects miniscule concentrations of hazardous materials in the air July 23rd, 2014

Announcements

Silicene Labs Announces the Launch of Patent-Pending, 2D Materials Composite Index™ : The Initial 2D Materials Composite Index™ for Q2 2014 Is: 857.3; Founders Include World-Renowned Physicist and Seasoned Business and IP Professionals July 24th, 2014

Iranian Scientists Produce Transparent Nanocomposite Coatings with Longer Lifetime July 24th, 2014

Deadline Announced for Registration in 7th Int'l Nanotechnology Festival in Iran July 23rd, 2014

A Crystal Wedding in the Nanocosmos July 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE