Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Bone Marrow Gets Targeted Drug Delivery

Abstract:
Bone marrow, the spongy, flexible tissue found in the center of bones, is essential for the production of blood cells. There are multiple diseases and infections that involve the bone marrow, but current strategies to treat these disorders involve intravenous delivery of drugs are not specifically targeted to the diseased marrow. The healthy cells in the body are also affected, leading to toxic side effects. Thus, there is an urgent need to develop targeted drug delivery strategies to diseased cells in the bone marrow.

Bone Marrow Gets Targeted Drug Delivery

Germany | Posted on August 19th, 2011

Recently, efforts in development of targeted drug delivery has heavily involved nanotechnology, which uses the strategy of active targeting. Porous silicon is an attractive material because of its biocompatibility and ability to carry various agents, from proteins to drugs and nanoparticles. In a new study featured in Advanced Healthcare Materials, Mauro Ferrari, David Gorenstein and their colleagues developed a system comprising nanoporous silicon particles and a cell adhesion molecule that specifically targets bone marrow and delivers a high amount of nanoparticles containing therapeutic drugs to the bone marrow tissue. The cell adhesion molecule, E-selectin, has recently shown promise as a biological target for the delivery of drug carriers to the bone marrow endothelium. The researchers attached a ligand that has a very high affinity to E-selectin to a porous silicon particle and successfully demonstrated its ability to deliver therapeutic liposomes.

These findings have the potential to further develop techniques to deliver currently available drugs specifically to the bone marrow, decreasing their side effects and improving their overall effectiveness in treating bone marrow associated disorders.

####

For more information, please click here

Copyright © Wiley-VCH Materials Science Journals

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

A. P. Mann et al., Adv. Mater., 2011 ; DOI: 10.1002/adma.201101541

Related News Press

News and information

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

SUNY Polytechnic Institute Invites the Public to Attend its Popular Statewide 'NANOvember' Series of Outreach and Educational Events October 23rd, 2014

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE