Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > "Smart” polymer capsules for dual-responsive drug delivery

Abstract:
Targeted drug delivery has grown into an extensively studied research field exploring methods which allow selective or protected drug/tissue interactions. Triggered release systems based on the presence of physiological stimuli, such as pH, enzymes and redox-potential, have recently emerged for advanced therapeutic delivery applications.

"Smart” polymer capsules for dual-responsive drug delivery

Melbourne, Australia | Posted on August 11th, 2011

Professor Frank Caruso and co-workers (University of Melbourne) have demonstrated how several independent release mechanisms can be brought together and synergistically function to tune cargo release profiles. They were able to generate a novel class of polymeric nano/microcapsules with dual-responsive release mechanisms via the versatile layer-by-layer technique and click chemistry.

These capsules could release cargo specifically in pH conditions that mimic intracellular acidic compartments. Further, the synergistic effects of pH and redox-potential allowed for rapid and efficient cargo release, even for extremely low intracellular reducing agent concentrations. The simple and efficient combination of the layer-by-layer technique and click chemistry for synthesizing "big-to-small" capsules with dual stimuli-responsive cargo release mechanisms broadens the possibilities for the design of "smart" capsules for intracellular therapeutic and diagnostic applications.

####

For more information, please click here

Copyright © John Wiley & Sons

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

K. Liang et al, Adv. Mater. ; DOI: 10.1002/adma.201101690

Related News Press

News and information

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Aculon Hires New Business Development Director December 19th, 2014

Iranian Scientists Use Nanotechnology to Increase Power, Energy of Supercapacitors December 18th, 2014

Nanomedicine

Creation of 'Rocker' protein opens way for new smart molecules in medicine, other fields December 18th, 2014

Iranian Researchers Produce Electrical Pieces Usable in Human Body December 18th, 2014

Zenosense, Inc. - Hospital Collaboration - 400 Person Lung Cancer Detection Trial December 17th, 2014

Unraveling the light of fireflies December 17th, 2014

Discoveries

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Creation of 'Rocker' protein opens way for new smart molecules in medicine, other fields December 18th, 2014

Iranian Scientists Use Nanotechnology to Increase Power, Energy of Supercapacitors December 18th, 2014

Announcements

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Aculon Hires New Business Development Director December 19th, 2014

Iranian Scientists Use Nanotechnology to Increase Power, Energy of Supercapacitors December 18th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE