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Home > News > Cancer Patient Saved With Lab-Grown Windpipe

July 7th, 2011

Cancer Patient Saved With Lab-Grown Windpipe

Abstract:
Doctors have replaced the cancer-stricken windpipe of a patient with an organ made in a lab, a landmark achievement for regenerative medicine. The patient no longer has cancer and is expected to have a normal life expectancy, doctors said.

"He was condemned to die," said Paolo Macchiarini, a professor of regenerative surgery who carried out the procedure at Sweden's Karolinska University Hospital. "We now plan to discharge him [Friday]."

A windpipe is a hollow tube made up of respiratory cells that sit atop a scaffold of various tissues, such as cartilage and muscle cells. As a first step, a team led by Alexander Seifalian of University College London used plastic materials and nanotechnology to make an artificial version of the scaffold in the lab. It was closely modeled on the shape and size of the Eritrean man's windpipe.

Source:
online.wsj.com

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