Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > New microsystem for better drug-testing

Abstract:
A University of Southampton nanoscientist is working on a new microsystem for more efficient testing of pharmaceutical drugs to treat diseases such as cystic fibrosis, MG (myasthenia gravis) and epilepsy.

New microsystem for better drug-testing

Southampton, UK | Posted on July 6th, 2011

Dr Maurits de Planque of ECS-Electronics and Computer Science at the University will develop a new method to investigate the ion channels that underlie these serious disorders and that are used to test the effectiveness of new drugs.

"At the moment, commercial testing of new drugs is carried out using ion channels in living cell membranes. This is a slow and difficult process, not least because producing too many channels actually kills the cells," said Dr de Planque

The researchers therefore plan to produce these ion channels without using cells, which is possible with so-called cell-free expression mixtures, and to insert the channels in a very stable artificial cell membrane which should enable faster, less expensive drug testing.

"Researchers have experimented with cell-free mixtures before, but they found that this method was not economical due to the amount of expensive biochemicals required," said Dr de Planque. "Our proposal to develop a new platform, which uses a couple of microlitres instead of millilitres, will be a very cost-effective way of doing this, particularly when the produced channel is directly inserted in a membrane for drug testing."

Dr de Planque is conducting this research over a two-year period in

collaboration with biological scientists at the University of Southampton. He is Principal Investigator for the project: Microsystems for Coupled Expression and Electrophysiology of Ion Channels, which has been awarded a grant of 125,000 from the Engineering and Physical Sciences Research Council (EPSRC).

####

About University of Southampton
.The University of Southampton is a leading UK teaching and research institution with a global reputation for research and scholarship across a wide range of subjects in engineering, science, social sciences, health, arts and humanities.

With over 22,000 students, around 5000 staff, and an annual turnover well in excess of 400 million, the University of Southampton is one of the country's top institutions for engineering, computer science and medicine. We combine academic excellence with an innovative and entrepreneurial approach to research, supporting a culture that engages and challenges students and staff in their pursuit of learning.

The University is also home to a number of world-leading research centres, including the Institute of Sound and Vibration Research, the Optoelectronics Research Centre, the Centre for the Developmental Origins of Health and Disease, the Southampton Statistical Sciences Research Institute and is a partner of the National Oceanography Centre at the Southampton waterfront campus.

About the School of Electronics and Computer Science at Southampton

With around 500 researchers, and 900 undergraduate students, the School of Electronics and Computer Science at Southampton is one of the world's largest and most successful integrated research groupings, covering Computer Science, Software Engineering, Electronics, Electrical Engineering, and IT in Organisations. ECS has unrivalled depth and breadth of expertise in world-leading research, new developments and their applications.

About EPSRC

EPSRC is the main UK government agency for funding research and training in engineering and the physical sciences, investing more than 850 million a year in a broad range of subjects from mathematics to materials science, and from information technology to structural engineering.

For more information, please click here

Contacts:
Helene Murphy
+44(0)20 8531 8000

Copyright © AlphaGalileo

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nano Ruffles in Brain Matter: Freiburg researchers decipher the role of nanostructures around brain cells in central nervous system function October 31st, 2014

Gold nanoparticle chains confine light to the nanoscale October 31st, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Device invented at Johns Hopkins provides up-close look at cancer on the move: Microscopic view of metastasis could give insight about how to keep cancer in check October 31st, 2014

Nanomedicine

Nano Ruffles in Brain Matter: Freiburg researchers decipher the role of nanostructures around brain cells in central nervous system function October 31st, 2014

Production of Biocompatible Polymers in Iran October 30th, 2014

Amorphous Coordination Polymer Particles as alternative to classical nanoplatforms for nanomedicine October 30th, 2014

'Electronic skin' could improve early breast cancer detection October 29th, 2014

Discoveries

Nano Ruffles in Brain Matter: Freiburg researchers decipher the role of nanostructures around brain cells in central nervous system function October 31st, 2014

Gold nanoparticle chains confine light to the nanoscale October 31st, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Device invented at Johns Hopkins provides up-close look at cancer on the move: Microscopic view of metastasis could give insight about how to keep cancer in check October 31st, 2014

Announcements

Nano Ruffles in Brain Matter: Freiburg researchers decipher the role of nanostructures around brain cells in central nervous system function October 31st, 2014

Gold nanoparticle chains confine light to the nanoscale October 31st, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Device invented at Johns Hopkins provides up-close look at cancer on the move: Microscopic view of metastasis could give insight about how to keep cancer in check October 31st, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE