Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Chemical & Engineering News Features Clarkson University Work on New Cancer Detection Method

Igor Sokolov
Igor Sokolov

Abstract:
An article in the May 23 issue of Chemical & Engineering News, a major news journal of the American Chemical Society, features work on cervical cancer cells done by Clarkson University Physics Professor Igor Sokolov's group with collaboration by Biology Professor Craig D. Woodworth.

Chemical & Engineering News Features Clarkson University Work on New Cancer Detection Method

Potsdam, NY | Posted on June 16th, 2011

The article, "Using the Force on Cancer," which was written by Associate Editor Lauren K. Wolf, analyzes the current state of research of the mechanics of tumor cells with atomic force microscopy and its possible use as a new non-traditional diagnostic tool of cancer.

Methods for the detection of cancer cells are mostly based on traditional techniques used in biology, such as visual identification of malignant changes, cell-growth analysis, or genetic tests.

Despite being well developed, these methods are either insufficiently accurate or require a lengthy complicated analysis, which is impractical for clinical use. There is a hope that the physical sciences can help to develop an alternative method in the detection of cancer cells, which will be more precise and simpler.

Sokolov's group, along with a number of other research groups, is trying to find unknown features of cancer cells that might be used for the detection and a better understanding of cancer.

"We focus on the study of mechanical properties of cell, which we study by means of atomic force microscopy (AFM), one of the major instruments responsible for the emergence of nanotechnology," says Sokolov.

Many researchers have demonstrated that cancerous cells are softer than normal ones. However, the group led by Sokolov found that this may not necessarily be the case. Studying human cancerous cervical cells, the group found that the rigidity of cancerous and normal cells does not differ significantly.

However, using an accurate model to describe the measurements, they found that the surface mechanical properties of cancerous and normal cells are considerably different.

"It is presently hard to compare results from different groups," says Sokolov. "Many groups use excessively sharp AFM probes, which causes non-linear cellular response, and consequently, can lead to incorrect numbers. We need a protocol -- what we can trust and what we can't."

He added that when diagnosing cancer, you don't want to make mistakes.

The team consists of Sokolov, who has appointments in Physics and Chemistry and Biomolecular Science; Woodworth, a cervical cancer expert; Maxim Dokukin, a physics postdoctoral fellow; and Ravi M. Gaikwad and Nataliaa Guz, physics graduate students.

The other members of Sokolov's group, Shajesh Palantavida (physics postdoctoral fellow), and Shyuzhene Li (physics graduate student), work on biosensors, self-assembly of particles, and the study of skin aging.

The research was done within the Nanoengineering and Biotechnology Laboratories Center (NABLAB) led by Sokolov, a unit established to promote cross-disciplinary collaborations within the University.

It comprises more than a dozen faculty members to capitalize on the expertise of Clarkson scholars in the areas of cancer cell research, fine particles for bio and medical applications, synthesis of smart materials, advancement biosensors, etc.

Clarkson University launches leaders into the global economy. One in six alumni already leads as a CEO, VP or equivalent senior executive of a company. Located just outside the Adirondack Park in Potsdam, N.Y., Clarkson is a nationally recognized research university for undergraduates with select graduate programs in signature areas of academic excellence directed toward the world's pressing issues. Through 50 rigorous programs of study in engineering, business, arts, sciences and health sciences, the entire learning-living community spans boundaries across disciplines, nations and cultures to build powers of observation, challenge the status quo, and connect discovery and engineering innovation with enterprise.

####

For more information, please click here

Contacts:
8 Clarkson Ave.
Potsdam, New York 13699
315-268-6400

Copyright © Clarkson University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

WITec to host the 11th Confocal Raman Imaging Symposium from September 29th - October 1st in Ulm, Germany July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Production of Toxic Gas Sensor Based on Nanorods July 28th, 2014

Bruker Announces Acquisition of High-Speed, 3D Super-Resolution Fluorescence Microscopy Company Vutara July 28th, 2014

Possible Futures

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Surface Characteristics Influence Cellular Growth on Semiconductor Material March 12th, 2014

Academic/Education

Haydale Announces Collaboration Agreement with Swansea University’s Welsh Centre for Printing and Coatings (WCPC) July 12th, 2014

STFC takes delivery of the 100th Hitachi Tabletop SEM in the UK July 3rd, 2014

Innovation Management and the Emergence of the Nanobiotechnology Industry July 1st, 2014

Albany NanoCollege Faculty Member Selected as Editor-in-Chief of the Prestigious Journal of Electronic Materials July 1st, 2014

Nanomedicine

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

Sensors

Production of Toxic Gas Sensor Based on Nanorods July 28th, 2014

Compact Vibration Harvester Power Supply with Highest Efficiency Opens Door to “Fix-and-Forget” Sensor Nodes July 23rd, 2014

Nano-sized Chip "Sniffs Out" Explosives Far Better than Trained Dogs: TAU researcher's groundbreaking sensor detects miniscule concentrations of hazardous materials in the air July 23rd, 2014

Tiny laser sensor heightens bomb detection sensitivity July 19th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE