Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Chemical & Engineering News Features Clarkson University Work on New Cancer Detection Method

Igor Sokolov
Igor Sokolov

Abstract:
An article in the May 23 issue of Chemical & Engineering News, a major news journal of the American Chemical Society, features work on cervical cancer cells done by Clarkson University Physics Professor Igor Sokolov's group with collaboration by Biology Professor Craig D. Woodworth.

Chemical & Engineering News Features Clarkson University Work on New Cancer Detection Method

Potsdam, NY | Posted on June 16th, 2011

The article, "Using the Force on Cancer," which was written by Associate Editor Lauren K. Wolf, analyzes the current state of research of the mechanics of tumor cells with atomic force microscopy and its possible use as a new non-traditional diagnostic tool of cancer.

Methods for the detection of cancer cells are mostly based on traditional techniques used in biology, such as visual identification of malignant changes, cell-growth analysis, or genetic tests.

Despite being well developed, these methods are either insufficiently accurate or require a lengthy complicated analysis, which is impractical for clinical use. There is a hope that the physical sciences can help to develop an alternative method in the detection of cancer cells, which will be more precise and simpler.

Sokolov's group, along with a number of other research groups, is trying to find unknown features of cancer cells that might be used for the detection and a better understanding of cancer.

"We focus on the study of mechanical properties of cell, which we study by means of atomic force microscopy (AFM), one of the major instruments responsible for the emergence of nanotechnology," says Sokolov.

Many researchers have demonstrated that cancerous cells are softer than normal ones. However, the group led by Sokolov found that this may not necessarily be the case. Studying human cancerous cervical cells, the group found that the rigidity of cancerous and normal cells does not differ significantly.

However, using an accurate model to describe the measurements, they found that the surface mechanical properties of cancerous and normal cells are considerably different.

"It is presently hard to compare results from different groups," says Sokolov. "Many groups use excessively sharp AFM probes, which causes non-linear cellular response, and consequently, can lead to incorrect numbers. We need a protocol -- what we can trust and what we can't."

He added that when diagnosing cancer, you don't want to make mistakes.

The team consists of Sokolov, who has appointments in Physics and Chemistry and Biomolecular Science; Woodworth, a cervical cancer expert; Maxim Dokukin, a physics postdoctoral fellow; and Ravi M. Gaikwad and Nataliaa Guz, physics graduate students.

The other members of Sokolov's group, Shajesh Palantavida (physics postdoctoral fellow), and Shyuzhene Li (physics graduate student), work on biosensors, self-assembly of particles, and the study of skin aging.

The research was done within the Nanoengineering and Biotechnology Laboratories Center (NABLAB) led by Sokolov, a unit established to promote cross-disciplinary collaborations within the University.

It comprises more than a dozen faculty members to capitalize on the expertise of Clarkson scholars in the areas of cancer cell research, fine particles for bio and medical applications, synthesis of smart materials, advancement biosensors, etc.

Clarkson University launches leaders into the global economy. One in six alumni already leads as a CEO, VP or equivalent senior executive of a company. Located just outside the Adirondack Park in Potsdam, N.Y., Clarkson is a nationally recognized research university for undergraduates with select graduate programs in signature areas of academic excellence directed toward the world's pressing issues. Through 50 rigorous programs of study in engineering, business, arts, sciences and health sciences, the entire learning-living community spans boundaries across disciplines, nations and cultures to build powers of observation, challenge the status quo, and connect discovery and engineering innovation with enterprise.

####

For more information, please click here

Contacts:
8 Clarkson Ave.
Potsdam, New York 13699
315-268-6400

Copyright © Clarkson University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

GLOBALFOUNDRIES to Expand Presence in China with 300mm Fab in Chongqing: Company plans new manufacturing facility and additional design capabilities to serve customers in China May 31st, 2016

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

UK NANOSAFETY GROUP publishes 2nd Edition of guidance to support safe working with nanomaterials May 30th, 2016

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Possible Futures

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Doubling down on Schrödinger's cat May 27th, 2016

Academic/Education

Graphene: Progress, not quantum leaps May 23rd, 2016

Smithsonian Science Education Center and National Space Society Team Up for Next-Generation Space Education Program "Enterprise In Space" May 11th, 2016

The University of Colorado Boulder, USA, combines Raman spectroscopy and nanoindentation for improved materials characterisation May 9th, 2016

Albertan Science Lab Opens in India May 7th, 2016

Nanomedicine

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Sensors

The next generation of carbon monoxide nanosensors May 26th, 2016

Dartmouth team creates new method to control quantum systems May 24th, 2016

Electronic device detects molecules linked to cancer, Alzheimer's and Parkinson's: An inexpensive portable biosensor has been developed by researchers at Brazil's National Nanotechnology Laboratory with FAPESP's support May 20th, 2016

Making organs transparent to improve nanomedicine (video) May 13th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic