Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Using chitosan derivatives to determine bactericidal activity

Abstract:
Researchers at National Nanotechnology Center, NANOTEC in Thailand, are doing research on the effects of the degree of quaternization, molecular weight and ratio of N-methylpyridinium and N,N,N-trimethyl ammonium moieties on bactericidal activity by introducing quaternization of N-(3-pyridylmethyl) chitosan derivatives.

Using chitosan derivatives to determine bactericidal activity

Pathumthani, Thailand | Posted on March 11th, 2011

"We found that the bactericidal activity was dependent on the chemical structure of quaternary ammonium moiety and the molecular weight, at constant DQ" said Dr. Warayuth Sajomsang, one of the research team members. "The result revealed that the N,N,N-trimethyl ammonium group showed higher bactericidal activity than the N-methylpyridinium group at similar DQ and molecular weight. Moreover, the bactericidal activity of M3-PyMeChC tended to decrease with decreasing molecular weight from 82 kDa to 8 kDa, at DQ of 802%".

"The bactericidal tests were performed in accordance with the National Committee for Clinical Laboratory Standards (NCCLS) to determine broth microdilution minimum inhibitory concentration (MIC) values" said Dr. Uracha Ruktanonchai, another member of the research team. "The microorganisms used in the inhibitory test were obtained from the Department of Medical Sciences (Ministry of Public Health, Thailand). The microorganisms used in this study were Staphylococcus aureus ATCC 6538 as a model for Grampositive bacteria and Escherichia coli ATCC 25922 as a model for Gram-negative bacteria".

The researchers reported their work in a paper published by Elsevier. The researchers at the NanoDelivery lab are currently working on research projects using nanoencapsulation and molecular complexation for controlled release and target delivery of bioactive compounds.

####

For more information, please click here

Contacts:
Ramjitti Indaraprasirt
Manager
International Relations Section
NANOTEC
02-564-7100 ext: 6617

113 Thailand Science Park
Phaholyothin Rd.
Klong 1, Klong Luang
Pathumthani 12120
Thailand

Copyright © NANOTEC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

The power of perovskite: OIST researchers improve perovskite-based technology in the entire energy cycle, from solar cells harnessing power to LED diodes to light the screens of future electronic devices and other lighting applications August 18th, 2017

Gold nanostars and immunotherapy vaccinate mice against cancer: New treatment cures, vaccinates mouse in small proof-of-concept study August 18th, 2017

Researchers printed graphene-like materials with inkjet August 17th, 2017

Candy cane supercapacitor could enable fast charging of mobile phones August 17th, 2017

Nanomedicine

Gold nanostars and immunotherapy vaccinate mice against cancer: New treatment cures, vaccinates mouse in small proof-of-concept study August 18th, 2017

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Discoveries

The power of perovskite: OIST researchers improve perovskite-based technology in the entire energy cycle, from solar cells harnessing power to LED diodes to light the screens of future electronic devices and other lighting applications August 18th, 2017

Gold nanostars and immunotherapy vaccinate mice against cancer: New treatment cures, vaccinates mouse in small proof-of-concept study August 18th, 2017

Researchers printed graphene-like materials with inkjet August 17th, 2017

Candy cane supercapacitor could enable fast charging of mobile phones August 17th, 2017

Announcements

The power of perovskite: OIST researchers improve perovskite-based technology in the entire energy cycle, from solar cells harnessing power to LED diodes to light the screens of future electronic devices and other lighting applications August 18th, 2017

Gold nanostars and immunotherapy vaccinate mice against cancer: New treatment cures, vaccinates mouse in small proof-of-concept study August 18th, 2017

Researchers printed graphene-like materials with inkjet August 17th, 2017

Candy cane supercapacitor could enable fast charging of mobile phones August 17th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project