Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Using chitosan derivatives to determine bactericidal activity

Abstract:
Researchers at National Nanotechnology Center, NANOTEC in Thailand, are doing research on the effects of the degree of quaternization, molecular weight and ratio of N-methylpyridinium and N,N,N-trimethyl ammonium moieties on bactericidal activity by introducing quaternization of N-(3-pyridylmethyl) chitosan derivatives.

Using chitosan derivatives to determine bactericidal activity

Pathumthani, Thailand | Posted on March 11th, 2011

"We found that the bactericidal activity was dependent on the chemical structure of quaternary ammonium moiety and the molecular weight, at constant DQ" said Dr. Warayuth Sajomsang, one of the research team members. "The result revealed that the N,N,N-trimethyl ammonium group showed higher bactericidal activity than the N-methylpyridinium group at similar DQ and molecular weight. Moreover, the bactericidal activity of M3-PyMeChC tended to decrease with decreasing molecular weight from 82 kDa to 8 kDa, at DQ of 80±2%".

"The bactericidal tests were performed in accordance with the National Committee for Clinical Laboratory Standards (NCCLS) to determine broth microdilution minimum inhibitory concentration (MIC) values" said Dr. Uracha Ruktanonchai, another member of the research team. "The microorganisms used in the inhibitory test were obtained from the Department of Medical Sciences (Ministry of Public Health, Thailand). The microorganisms used in this study were Staphylococcus aureus ATCC 6538 as a model for Grampositive bacteria and Escherichia coli ATCC 25922 as a model for Gram-negative bacteria".

The researchers reported their work in a paper published by Elsevier. The researchers at the NanoDelivery lab are currently working on research projects using nanoencapsulation and molecular complexation for controlled release and target delivery of bioactive compounds.

####

For more information, please click here

Contacts:
Ramjitti Indaraprasirt
Manager
International Relations Section
NANOTEC
02-564-7100 ext: 6617

113 Thailand Science Park
Phaholyothin Rd.
Klong 1, Klong Luang
Pathumthani 12120
Thailand

Copyright © NANOTEC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

MEMS & Sensors Technology Showcase: Finalists Announced for MEMS Executive Congress US 2014 October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Advancing thin film research with nanostructured AZO: Innovnano’s unique and cost-effective AZO sputtering targets for the production of transparent conducting oxides October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE