Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > How Safe Is Nano?

Abstract:
Nanotoxicology: An interdisciplinary challenge

How Safe Is Nano?

Weinheim, Germany | Posted on January 28th, 2011

The rapid development of nanotechnology has increased fears about the health risks of nano-objects. Are these fears justified? Do we need a new discipline, nanotoxicology, to evaluate the risks? Harald F. Krug and Peter Wick of the Swiss Federal Laboratories for Materials Science and Technology discuss these questions in the journal Angewandte Chemie.

"Research into the safety of nanotechnology combines biology, chemistry, and physics with workplace hygiene, materials science, and engineering to create a truly interdisciplinary research field," explain Krug and Wick. "There are several factors to take into account in the interaction of nano-objects with organisms," they add. The term nanotoxicology is fully justified. "Nanoscale particles can enter into cells by other means of transport than larger particles." Another critical feature is the large surface area of nano-objects relative to their volume. If a similar amount of substance is absorbed, an organism comes into contact with a significantly larger number of molecules with nanoparticles than with larger particles. Dose-effect relationships cannot therefore be assumed to be the same. Furthermore, chemical and physical effects that do not occur with larger particles may arise. "Whether the larger or smaller particle is more toxic in any given case cannot be predicted," according to the authors. "Clearly, the type of chemical compound involved and its conformation in a specific case can also not be ignored." Carbon in the form of diamond nanoparticles is harmless, whereas in the form of nanotubes—depending on length and degree of aggregation—it may cause health problems. It is also thus impossible to avoid considering each nanomaterial in turn.

For a risk assessment, it is also necessary to keep in mind what dosage would be considered realistic and that not every observed biological effect automatically equates to a health risk.

Krug and Wick indicate that a large amount of data about the biological effects of nanomaterials is available, but not all studies are reliable. Sometimes it is not possible to reproduce the specific material tested or the conditions. "By pointing out methodological inadequacies and making concrete recommendations for avoiding them, we are hoping to contribute to a lasting improvement in the data," state Krug and Wick.

About the authors: Krug is Director of the "Materials Meet Life" department at the Swiss Federal Laboratories for Materials Science and Technology (Empa), member of the Governing Board of the DECHEMA (Society for Chemical Engineering and Biotechnology) working group on the responsible use of nanomaterials, and advises German federal government departments, as well as government departments in Switzerland, on the subject of nanotechnology. Wick is Director of the Materials-Biology Interactions division of Empa and works on national and international projects concerned with nano-safety as well as serving on the Editorial Board of the journal Nanotoxicology.

Author: Harald F. Krug, Empa-Materials Science & Technology, St. Gallen (Switzerland), www.empa.ch/abt274

Title: Nanotoxicology: An Interdisciplinary Challenge

Angewandte Chemie International Edition, Permalink dx.doi.org/10.1002/anie.201001037

####

For more information, please click here

Copyright © Angewandte Chemie International Edition

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Physics

Superfast light source made from artificial atom April 28th, 2016

Physicists detect the enigmatic spin momentum of light April 26th, 2016

The atom without properties April 22nd, 2016

Chemistry

Adding some salt to the recipe for energy storage materials: Researchers use common table salt as growth template April 22nd, 2016

NRL reveals novel uniform coating process of p-ALD April 21st, 2016

Team builds first quantum cascade laser on silicon: Eliminates the need for an external light source for mid-infrared silicon photonic devices or photonic circuits April 21st, 2016

Preparing for Nano

Nanotechnology is changing everything from medicine to self-healing buildings: Nanotechnology is so small it's measured in billionths of metres, and it is revolutionising every aspect of our lives April 2nd, 2016

Durnham University's DEEPEN project comes to a close September 26th, 2012

Technical Seminar at ANFoS 2012 August 22nd, 2012

Nanotechnology shows we can innovate without economic growth April 12th, 2012

Govt.-Legislation/Regulation/Funding/Policy

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Academic/Education

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

The Ottawa Hospital Research Institute uses the ZetaView from Particle Metrix to study membrane microparticles as potential biomarkers for underlying diseases April 12th, 2016

FEI Partners with Five Pharmaceutical Companies, the Medical Research Council and the University of Cambridge to form Cryo-EM Research Consortium April 5th, 2016

SUNY Poly, in Collaboration with the George Washington School of Medicine and Health Sciences and Stony Brook University, Demonstrates Pioneering Method to Visualize and Identify Engineered Nanoparticles in Tissue March 25th, 2016

Announcements

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Safety-Nanoparticles/Risk management

Scientists propose non-animal tools for assessing the toxicity of nanomaterials: Particle and Fibre Toxicology publishes recommendations from expert group meeting April 26th, 2016

The impact of anti-odor clothing on the environment March 31st, 2016

SUNY Poly, in Collaboration with the George Washington School of Medicine and Health Sciences and Stony Brook University, Demonstrates Pioneering Method to Visualize and Identify Engineered Nanoparticles in Tissue March 25th, 2016

Microagents with revolutionary potential March 24th, 2016

Nanobiotechnology

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic