Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > How Safe Is Nano?

Abstract:
Nanotoxicology: An interdisciplinary challenge

How Safe Is Nano?

Weinheim, Germany | Posted on January 28th, 2011

The rapid development of nanotechnology has increased fears about the health risks of nano-objects. Are these fears justified? Do we need a new discipline, nanotoxicology, to evaluate the risks? Harald F. Krug and Peter Wick of the Swiss Federal Laboratories for Materials Science and Technology discuss these questions in the journal Angewandte Chemie.

"Research into the safety of nanotechnology combines biology, chemistry, and physics with workplace hygiene, materials science, and engineering to create a truly interdisciplinary research field," explain Krug and Wick. "There are several factors to take into account in the interaction of nano-objects with organisms," they add. The term nanotoxicology is fully justified. "Nanoscale particles can enter into cells by other means of transport than larger particles." Another critical feature is the large surface area of nano-objects relative to their volume. If a similar amount of substance is absorbed, an organism comes into contact with a significantly larger number of molecules with nanoparticles than with larger particles. Dose-effect relationships cannot therefore be assumed to be the same. Furthermore, chemical and physical effects that do not occur with larger particles may arise. "Whether the larger or smaller particle is more toxic in any given case cannot be predicted," according to the authors. "Clearly, the type of chemical compound involved and its conformation in a specific case can also not be ignored." Carbon in the form of diamond nanoparticles is harmless, whereas in the form of nanotubes—depending on length and degree of aggregation—it may cause health problems. It is also thus impossible to avoid considering each nanomaterial in turn.

For a risk assessment, it is also necessary to keep in mind what dosage would be considered realistic and that not every observed biological effect automatically equates to a health risk.

Krug and Wick indicate that a large amount of data about the biological effects of nanomaterials is available, but not all studies are reliable. Sometimes it is not possible to reproduce the specific material tested or the conditions. "By pointing out methodological inadequacies and making concrete recommendations for avoiding them, we are hoping to contribute to a lasting improvement in the data," state Krug and Wick.

About the authors: Krug is Director of the "Materials Meet Life" department at the Swiss Federal Laboratories for Materials Science and Technology (Empa), member of the Governing Board of the DECHEMA (Society for Chemical Engineering and Biotechnology) working group on the responsible use of nanomaterials, and advises German federal government departments, as well as government departments in Switzerland, on the subject of nanotechnology. Wick is Director of the Materials-Biology Interactions division of Empa and works on national and international projects concerned with nano-safety as well as serving on the Editorial Board of the journal Nanotoxicology.

Author: Harald F. Krug, Empa-Materials Science & Technology, St. Gallen (Switzerland), www.empa.ch/abt274

Title: Nanotoxicology: An Interdisciplinary Challenge

Angewandte Chemie International Edition, Permalink dx.doi.org/10.1002/anie.201001037

####

For more information, please click here

Copyright © Angewandte Chemie International Edition

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Physics

Solid state physics: Quantum matter stuck in unrest August 1st, 2015

Meet the high-performance single-molecule diode: Major milestone in molecular electronics scored by Berkeley Lab and Columbia University team July 29th, 2015

Detecting small metallic contaminants in food via magnetization: A practical metallic-contaminant detecting system using three high-Tc RF superconducting quantum interference devices (SQUIDs) July 29th, 2015

News and information

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Harris & Harris Group Portfolio Company, HZO, Announces Partnerships with Dell and Motorola August 1st, 2015

Advances and Applications in Biosensing, Sensor Power, and Sensor R&D to be Covered at Sensors Global Summit August 1st, 2015

Kalam: versatility personified August 1st, 2015

Chemistry

March 2016; 6th Int'l Conference on Nanostructures in Iran July 29th, 2015

Meet the high-performance single-molecule diode: Major milestone in molecular electronics scored by Berkeley Lab and Columbia University team July 29th, 2015

Preparing for Nano

Durnham University's DEEPEN project comes to a close September 26th, 2012

Technical Seminar at ANFoS 2012 August 22nd, 2012

Nanotechnology shows we can innovate without economic growth April 12th, 2012

Thailand to host NanoThailand 2012 December 18th, 2011

Govt.-Legislation/Regulation/Funding/Policy

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Kalam: versatility personified August 1st, 2015

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

Theoretical Physicists at Freie Universität Berlin Develop New Insights into Interface between Classical and Quantum Worlds July 31st, 2015

Academic/Education

Pakistani Students Who Survived Terror Attack to Attend Weeklong “NanoDiscovery Institute” at SUNY Poly CNSE in Albany July 29th, 2015

Deben reports on the use of their CT500 in the X-ray microtomography laboratory at La Trobe University, Melbourne, Australia July 22nd, 2015

JPK reports on the use of SPM in the Messersmith Group at UC Berkeley looking at biologically inspired polymer adhesives. July 21st, 2015

Renishaw adds Raman analysis to Scanning Electron Microscopy at the University of Sydney, Australia July 9th, 2015

Announcements

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Harris & Harris Group Portfolio Company, HZO, Announces Partnerships with Dell and Motorola August 1st, 2015

Advances and Applications in Biosensing, Sensor Power, and Sensor R&D to be Covered at Sensors Global Summit August 1st, 2015

Safety-Nanoparticles/Risk management

March 2016; 6th Int'l Conference on Nanostructures in Iran July 29th, 2015

Environmentally friendly lignin nanoparticle 'greens' silver nanobullet to battle bacteria July 13th, 2015

NIST ‘How-To’ Website Documents Procedures for Nano-EHS Research and Testing July 1st, 2015

Proposed TSCA Nanomaterial Rule ‘Premature’, Says Former EPA Toxicologist July 1st, 2015

Nanobiotechnology

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

European Technology Platform for Nanomedicine and ENATRANS European Consortium Launch the 2nd edition of the Nanomedicine Award: The Award to be presented at BIO-Europe conference in Munich, November 2015 July 30th, 2015

New computer model could explain how simple molecules took first step toward life: Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules July 28th, 2015

Spintronics: Molecules stabilizing magnetism: Organic molecules fixing the magnetic orientation of a cobalt surface/ building block for a compact and low-cost storage technology/ publication in Nature Materials July 25th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project