Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > DNA Weaving

DNA origami gets large: A double-layer DNA-origami tile with two orthogonal domains underwent self-assembly into well-ordered 2D DNA arrays with edge dimensions of 2ĘC3 Ž╠m (see schematic representation and AFM image). This size is likely to be large enough to connect bottom-up methods of patterning with top-down approaches.
DNA origami gets large: A double-layer DNA-origami tile with two orthogonal domains underwent self-assembly into well-ordered 2D DNA arrays with edge dimensions of 2ĘC3 Ž╠m (see schematic representation and AFM image). This size is likely to be large enough to connect bottom-up methods of patterning with top-down approaches.

Abstract:
Two-dimensional crystals from DNA origami tiles

DNA Weaving

Weinheim, Germany | Posted on November 16th, 2010

DNA is more than just a carrier for our genetic information; DNA is also an outstanding nanoscale building material, as researchers led by Ned Seeman discovered thirty years ago. Seeman and his colleagues at the New York University (USA) have now used cross-shaped DNA tiles to produce an amazingly large grid structure that resembles woven fabric. As the researchers report in the journal Angewandte Chemie, these two-dimensional crystals attain dimensions of about 2í┴3 micrometers.

The specific pairing of complementary bases makes DNA an ideal nanoscale building component. It is possible to incorporate particular base sequences that specifically bind to their counterparts. These are called í░sticky endsí▒, and can be used to assemble tailored structures. Many nanostructures and nanomachines have previously been made from DNA. This technology experienced an upsurge a few years ago because of a new twist: the DNA origami technique developed by Paul Rothemund. As in origami, the Japanese art of paper folding, a long single strand of DNA is folded into a desired three-dimensional shape through short synthetic DNA oligonucleotides.

Seeman and his co-workers have also made use of this technique. They used this origami method to fold the DNA into the shapes they needed: cross-shaped tiles. The crosses consist of two mutually orthogonal overlapping strips, like two plasters stuck on top of each other to make a cross. On the four sides of the cross there are several sticky ends; the sticky ends opposite each other are identical. The researchers used two different sets of origami crosses with different sticky ends. These ends are designed so that the crosses bind together in an alternating pattern through a self-organization processí¬such that the lower strip of one cross is always bound to the upper strip of its neighbor. This results in a two-dimensional structure that has a lattice-like woven appearance when viewed through an electron microscope. The alternating construction of upward and downward curved crosses is necessary to produce a planar surface. Randomly assembled crosses often lead to tubular structures.

í░Our new approach could smooth the way for the industrial production of nanostructures through molecular self-organization processes,í▒ hopes Seeman.

Author: Nadrian C. Seeman, New York University (USA), chemistry.fas.nyu.edu/object/nadriancseeman.html

Title: Crystalline Two-Dimensional DNA Origami Arrays

Angewandte Chemie International Edition, Permalink to the article: dx.doi.org/10.1002/anie.201005911

####

For more information, please click here

Copyright © Angewandte Chemie

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Oxford Instruments announces Dr Kate Ross as winner of the 2018 Lee Osheroff Richardson Science Prize for North and South America February 20th, 2018

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

Possible Futures

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Rutgers-Led Innovation Could Spur Faster, Cheaper, Nano-Based Manufacturing: Scalable and cost-effective manufacturing of thin film devices February 14th, 2018

Academic/Education

Luleň University of Technology is using the Deben CT5000TEC stage to perform x-ray microtomography experiments with the ZEISS Xradia 510 Versa to understand deformation and strain inside inhomogeneous materials November 7th, 2017

Park Systems Announces the Grand Opening of the Park NanoScience Center at SUNY Polytechnic Institute November 3rd, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Moving at the Speed of Light: University of Arizona selected for high-impact, industrial demonstration of new integrated photonic cryogenic datalink for focal plane arrays: Program is major milestone for AIM Photonics August 10th, 2017

Self Assembly

Liquid crystal molecules form nano rings: Quantized self-assembly enables design of materials with novel properties February 7th, 2018

Particle size matters for porous building blocks: Rice University scientists find porous nanoparticles get tougher under pressure, but not when assembled December 19th, 2017

Physicists gain new insights into nanosystems with spherical confinement: Enormous potential for the targeted delivery of pharmaceutical agents and the creation of tailored nanoparticles July 27th, 2017

Oddball enzyme provides easy path to synthetic biomaterials May 17th, 2017

Nanomedicine

Arrowhead Receives Regulatory Clearance to Begin Phase 1/2 Study of ARO-HBV for Treatment of Hepatitis B February 15th, 2018

Arrowhead Pharmaceuticals Receives Orphan Drug Designation for ARO-AAT February 15th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Understanding brain functions using upconversion nanoparticles: Researchers can now send light deep into the brain to study neural activities February 14th, 2018

Announcements

Oxford Instruments announces Dr Kate Ross as winner of the 2018 Lee Osheroff Richardson Science Prize for North and South America February 20th, 2018

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

Industrial

Ultra-efficient removal of carbon monoxide using gold nanoparticles on a molecular support: New method and mechanism for state-of-the-art gas purification February 9th, 2018

A simple new approach to plastic solar cells: Osaka University researchers intelligently design new highly efficient organic solar cells based on amorphous electronic materials with potential for easy printing January 28th, 2018

Nature paper by Schlumberger researchers used photothermal based nanoscale IR spectroscopy to analyze heterogeneous process of petroleum generation January 23rd, 2018

New filters could enable manufacturers to perform highly-selective chemical separation January 23rd, 2018

Nanobiotechnology

Arrowhead Receives Regulatory Clearance to Begin Phase 1/2 Study of ARO-HBV for Treatment of Hepatitis B February 15th, 2018

Arrowhead Pharmaceuticals Receives Orphan Drug Designation for ARO-AAT February 15th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Understanding brain functions using upconversion nanoparticles: Researchers can now send light deep into the brain to study neural activities February 14th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project