Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > DNA Weaving

DNA origami gets large: A double-layer DNA-origami tile with two orthogonal domains underwent self-assembly into well-ordered 2D DNA arrays with edge dimensions of 2¨C3 ¦Ìm (see schematic representation and AFM image). This size is likely to be large enough to connect bottom-up methods of patterning with top-down approaches.
DNA origami gets large: A double-layer DNA-origami tile with two orthogonal domains underwent self-assembly into well-ordered 2D DNA arrays with edge dimensions of 2¨C3 ¦Ìm (see schematic representation and AFM image). This size is likely to be large enough to connect bottom-up methods of patterning with top-down approaches.

Abstract:
Two-dimensional crystals from DNA origami tiles

DNA Weaving

Weinheim, Germany | Posted on November 16th, 2010

DNA is more than just a carrier for our genetic information; DNA is also an outstanding nanoscale building material, as researchers led by Ned Seeman discovered thirty years ago. Seeman and his colleagues at the New York University (USA) have now used cross-shaped DNA tiles to produce an amazingly large grid structure that resembles woven fabric. As the researchers report in the journal Angewandte Chemie, these two-dimensional crystals attain dimensions of about 2¡Á3 micrometers.

The specific pairing of complementary bases makes DNA an ideal nanoscale building component. It is possible to incorporate particular base sequences that specifically bind to their counterparts. These are called ¡°sticky ends¡±, and can be used to assemble tailored structures. Many nanostructures and nanomachines have previously been made from DNA. This technology experienced an upsurge a few years ago because of a new twist: the DNA origami technique developed by Paul Rothemund. As in origami, the Japanese art of paper folding, a long single strand of DNA is folded into a desired three-dimensional shape through short synthetic DNA oligonucleotides.

Seeman and his co-workers have also made use of this technique. They used this origami method to fold the DNA into the shapes they needed: cross-shaped tiles. The crosses consist of two mutually orthogonal overlapping strips, like two plasters stuck on top of each other to make a cross. On the four sides of the cross there are several sticky ends; the sticky ends opposite each other are identical. The researchers used two different sets of origami crosses with different sticky ends. These ends are designed so that the crosses bind together in an alternating pattern through a self-organization process¡ªsuch that the lower strip of one cross is always bound to the upper strip of its neighbor. This results in a two-dimensional structure that has a lattice-like woven appearance when viewed through an electron microscope. The alternating construction of upward and downward curved crosses is necessary to produce a planar surface. Randomly assembled crosses often lead to tubular structures.

¡°Our new approach could smooth the way for the industrial production of nanostructures through molecular self-organization processes,¡± hopes Seeman.

Author: Nadrian C. Seeman, New York University (USA), chemistry.fas.nyu.edu/object/nadriancseeman.html

Title: Crystalline Two-Dimensional DNA Origami Arrays

Angewandte Chemie International Edition, Permalink to the article: dx.doi.org/10.1002/anie.201005911

####

For more information, please click here

Copyright © Angewandte Chemie

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Non-animal approach to predict impact of nanomaterials on human lung published Archives of Toxicology publishes workshop recommendations May 2nd, 2016

Making invisible physics visible: The Jayich Lab has created a new sensor technology that captures nanoscale images with high spatial resolution and sensitivity May 2nd, 2016

New drug-delivery approach holds potential for treating obesity May 2nd, 2016

Spintronics for future information technologies: Spin currents in topological insulators controlled May 2nd, 2016

Possible Futures

Making invisible physics visible: The Jayich Lab has created a new sensor technology that captures nanoscale images with high spatial resolution and sensitivity May 2nd, 2016

New drug-delivery approach holds potential for treating obesity May 2nd, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Academic/Education

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

The Ottawa Hospital Research Institute uses the ZetaView from Particle Metrix to study membrane microparticles as potential biomarkers for underlying diseases April 12th, 2016

FEI Partners with Five Pharmaceutical Companies, the Medical Research Council and the University of Cambridge to form Cryo-EM Research Consortium April 5th, 2016

SUNY Poly, in Collaboration with the George Washington School of Medicine and Health Sciences and Stony Brook University, Demonstrates Pioneering Method to Visualize and Identify Engineered Nanoparticles in Tissue March 25th, 2016

Self Assembly

Searching for a nanotech self-organizing principle May 1st, 2016

Researchers create artificial protein to control assembly of buckyballs April 27th, 2016

Brookhaven's Oleg Gang Named a Battelle 'Inventor of the Year': Recognized for work using DNA to guide and regulate the self-assembly of nanoparticles into clusters and arrays with controllable properties April 25th, 2016

Researchers develop new semiconducting polymer for forthcoming flexible electronics April 21st, 2016

Nanomedicine

Non-animal approach to predict impact of nanomaterials on human lung published Archives of Toxicology publishes workshop recommendations May 2nd, 2016

New drug-delivery approach holds potential for treating obesity May 2nd, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Announcements

Non-animal approach to predict impact of nanomaterials on human lung published Archives of Toxicology publishes workshop recommendations May 2nd, 2016

Making invisible physics visible: The Jayich Lab has created a new sensor technology that captures nanoscale images with high spatial resolution and sensitivity May 2nd, 2016

New drug-delivery approach holds potential for treating obesity May 2nd, 2016

Spintronics for future information technologies: Spin currents in topological insulators controlled May 2nd, 2016

Industrial

Novel anti-biofilm nano coating developed at Ben-Gurion U.: Offers significant anti-adhesive potential for a variety of medical and industrial applications April 25th, 2016

Model aids efforts to reduce cost of carbon nanostructures for industry, research April 5th, 2016

Molecular-scale ALD discovery could have industrial-sized impact: New atomic layer deposition technique reduces waste March 31st, 2016

Transparent wood could one day help brighten homes and buildings March 31st, 2016

Nanobiotechnology

New drug-delivery approach holds potential for treating obesity May 2nd, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic