Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > DNA Weaving

DNA origami gets large: A double-layer DNA-origami tile with two orthogonal domains underwent self-assembly into well-ordered 2D DNA arrays with edge dimensions of 2¨C3 ¦Ìm (see schematic representation and AFM image). This size is likely to be large enough to connect bottom-up methods of patterning with top-down approaches.
DNA origami gets large: A double-layer DNA-origami tile with two orthogonal domains underwent self-assembly into well-ordered 2D DNA arrays with edge dimensions of 2¨C3 ¦Ìm (see schematic representation and AFM image). This size is likely to be large enough to connect bottom-up methods of patterning with top-down approaches.

Abstract:
Two-dimensional crystals from DNA origami tiles

DNA Weaving

Weinheim, Germany | Posted on November 16th, 2010

DNA is more than just a carrier for our genetic information; DNA is also an outstanding nanoscale building material, as researchers led by Ned Seeman discovered thirty years ago. Seeman and his colleagues at the New York University (USA) have now used cross-shaped DNA tiles to produce an amazingly large grid structure that resembles woven fabric. As the researchers report in the journal Angewandte Chemie, these two-dimensional crystals attain dimensions of about 2¡Á3 micrometers.

The specific pairing of complementary bases makes DNA an ideal nanoscale building component. It is possible to incorporate particular base sequences that specifically bind to their counterparts. These are called ¡°sticky ends¡±, and can be used to assemble tailored structures. Many nanostructures and nanomachines have previously been made from DNA. This technology experienced an upsurge a few years ago because of a new twist: the DNA origami technique developed by Paul Rothemund. As in origami, the Japanese art of paper folding, a long single strand of DNA is folded into a desired three-dimensional shape through short synthetic DNA oligonucleotides.

Seeman and his co-workers have also made use of this technique. They used this origami method to fold the DNA into the shapes they needed: cross-shaped tiles. The crosses consist of two mutually orthogonal overlapping strips, like two plasters stuck on top of each other to make a cross. On the four sides of the cross there are several sticky ends; the sticky ends opposite each other are identical. The researchers used two different sets of origami crosses with different sticky ends. These ends are designed so that the crosses bind together in an alternating pattern through a self-organization process¡ªsuch that the lower strip of one cross is always bound to the upper strip of its neighbor. This results in a two-dimensional structure that has a lattice-like woven appearance when viewed through an electron microscope. The alternating construction of upward and downward curved crosses is necessary to produce a planar surface. Randomly assembled crosses often lead to tubular structures.

¡°Our new approach could smooth the way for the industrial production of nanostructures through molecular self-organization processes,¡± hopes Seeman.

Author: Nadrian C. Seeman, New York University (USA), chemistry.fas.nyu.edu/object/nadriancseeman.html

Title: Crystalline Two-Dimensional DNA Origami Arrays

Angewandte Chemie International Edition, Permalink to the article: dx.doi.org/10.1002/anie.201005911

####

For more information, please click here

Copyright © Angewandte Chemie

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cells June 30th, 2015

BASF and Fraunhofer IPMS-CNT jointly develop electronic materials June 30th, 2015

Researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th, 2015

Oxford Instruments’ TritonXL Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th, 2015

Possible Futures

Harris & Harris Group Portfolio Company D-Wave Systems Announces 1,000 Qubit Processor and is Discussed in the Economist June 23rd, 2015

Global Nanoclays Market Analysis, Size, Growth, Trends And Segment Forecasts, 2015 To 2022: Grand View Research, Inc June 15th, 2015

Healthcare Nanotechnology (Nanomedicine) Market Size To 2020 June 5th, 2015

Environmental Issues to Hamper Growth of Global Nanocomposites Market June 4th, 2015

Academic/Education

Oxford Instruments’ TritonXL Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th, 2015

Rice University boots up powerful microscopes: New electron microscopes will capture images at subnanometer resolution June 29th, 2015

Six top Catalan research centres constitute ‘The Barcelona Institute of Science and Technology’ to pursue a joint scientific endeavour June 27th, 2015

Lancaster University revolutionary quantum technology research receives funding boost June 22nd, 2015

Self Assembly

New conductive ink for electronic apparel June 25th, 2015

Giving atoms their marching orders: Highly homogeneous nanotube enforces single-file flow of atoms in gas diffusion. Direct comparison of single-file and Fickian diffusion possible with new system described by researchers at the University of South Carolina and University of Flor June 24th, 2015

n-tech Research Issues Report on Smart Coatings Market, Free Download Available on Firm’s Website June 24th, 2015

Sweeping lasers snap together nanoscale geometric grids: New technique creates multi-layered, self-assembled grids with fully customizable shapes and compositions June 23rd, 2015

Nanomedicine

Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cells June 30th, 2015

Researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th, 2015

Efforts to Use Smart Nanocarriers to Cure Leukemia Yield Promising Results June 29th, 2015

Chivalrous Knight Does Pro Bono June 27th, 2015

Announcements

BASF and Fraunhofer IPMS-CNT jointly develop electronic materials June 30th, 2015

Graphene flexes its electronic muscles: Rice-led researchers calculate electrical properties of carbon cones, other shapes June 30th, 2015

Researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th, 2015

Oxford Instruments’ TritonXL Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th, 2015

Industrial

Green Chemistry Methods Used in Iran to Produce Zinc Oxide Nanoparticles June 27th, 2015

Stanford researchers stretch a thin crystal to get better solar cells June 25th, 2015

Silica 'spiky screws' could enhance industrial coatings, additive manufacturing June 24th, 2015

Research findings point way to designing crack-resistant metals June 24th, 2015

Nanobiotechnology

Nanometric sensor designed to detect herbicides can help diagnose multiple sclerosis June 23rd, 2015

Newly-Developed Biosensor in Iran Detects Cocaine Addiction June 23rd, 2015

Researchers first to show that Saharan silver ants can control electromagnetic waves over an extremely broad range of the electromagnetic spectrum—findings may lead to biologically inspired coatings for passive radiative cooling of objects June 19th, 2015

Cellulose from wood can be printed in 3-D June 17th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project