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Providing optimum flow smoothness for microfluidic applications
As a world leader in microfluidic design, Dolomite is dedicated to providing highly optimised equipment for a range of microfluidic applications. The recently launched Mitos P-Pump provides a pulseless liquid flow, using a precise pressure driven pumping mechanism. With excellent response time and accuracy, this pressure driven flow is ideal for microfluidic systems where a highly stable flow is required. This includes applications such as compartmentalised chemistry and alginate polymerisation, which necessitate the stable formation of oil-in-water or water-in-oil droplets; however their monodispersity (size consistency) is key to obtaining accurate and repeatable results.
Dolomite has therefore carried out a number of tests to compare the size consistency of droplets formed by the Mitos P-Pump with market leading syringe pumps. Droplets of water-in-oil were generated on a 100µm sized X-Junction, using each of the pump technologies. The droplet diameter from a continuous stream was measured using image analysis software. The resulting data demonstrated that the Mitos P-Pump provides a coefficient of variation in the droplet diameter of less than 0.6%, compared with 5.5% for the leading syringe pump. Its precise pressure-driven pumping mechanism delivers liquid with a smooth and even flow, whereas even the best motor drives and mechanics of a syringe pump have slight non-linearities, which cause unwanted pulsation. The Mitos P-Pump technology therefore provides the best solution for droplet formation applications.
To download the complete study, and for further information on the Mitos P-Pump as well as Dolomite's portfolio of microfluidic products, including chips, connectors/interconnects, pumps, valves and flow sensors, please visit www.dolomite-microfluidics.com.
Established in 2005 as the world’s first Microfluidic Application Centre, Dolomite focused on working with customers to turn their concepts for microfluidic applications into reality. Today, Dolomite is the world leader in solving microfluidic problems. With offices in the UK and US and distributors throughout the rest of the world, its clients range from universities developing leading-edge analytical equipment, to manufacturers of chemical, life science and clinical diagnostics systems.
Dolomite is pioneering the use of microfluidic devices for small-scale fluid control and analysis, enabling manufacturers to develop more compact, cost-effective and powerful instruments. By combining specialist glass, quartz and ceramic technologies with knowledge of high performance microfluidics, Dolomite is able to provide solutions for a broad range of application areas including environmental monitoring, clinical diagnostics, food and beverage, nuclear, agriculture, petrochemical, cosmetics, pharmaceuticals and chemicals. Furthermore Dolomite's in-house micro-fabrication facilities that include clean rooms and precision glass processing facilities allow to prototype and test all solutions rapidly which ensures a faster development cycle and reduces the time to market.
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