Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Rheological technique predicts stability of SLNs

Dr. Uracha Ruktanonchai
Dr. Uracha Ruktanonchai

Abstract:
A rheological technique, used by researchers at National Nanotechnology Center (NANOTEC) in Thailand has revealed the instability of y-oryzanol-loaded solid lipid nanoparticles (SLNs) over 60 days storage at three different temperatures of 4, 25, and 40║C.

Rheological technique predicts stability of SLNs

Thailand | Posted on August 24th, 2010

"Upon storage, gelation was developed in all samples, especially at 40║C" said Dr. Uracha Ruktanonchai, Research Leader at Nano Delivery Lab, NANOTEC. "Rheological technique helps us in revealing this instability which is attributed by the increase in storage modulus, critical stress, and the characteristic relaxation time."

SLNs have gained interest as colloidal drug carriers due to their submicron size, potential for industrial production, and their physiological compositions. The carrier has been used for effective controlled-release and prolonged stability of both lipophilic and hydrophilic drugs. One of the lipophilic drugs found applications in cosmetic, pharmaceutical, and food areas is a natural antioxidant y-oryzanol, a main constituent in rice bran oil. Temperature and light exposure during storage have found to affect the stability of the nanoparticle.

The researchers reported their work in a paper published by Micron, the international research and review journal for microscopy. Collaborators on this investigation included National Metal and Materials Technology Center, National Science and Technology Development Agency, Thailand.

Dr. Uracha is currently exploring the fabrication of lipid nanoparticles and nanodispersion together with the characteristics of the resulting nanostructures particularly for medical and agricultural applications.

####

For more information, please click here

Contacts:
Media contact:
Ramjitti Indaraprasirt
Manager
International Relations Section
NANOTEC
02-564-7100 ext: 6617

Copyright © NANOTEC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Oxford Instruments announces Dr Kate Ross as winner of the 2018 Lee Osheroff Richardson Science Prize for North and South America February 20th, 2018

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

Possible Futures

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Rutgers-Led Innovation Could Spur Faster, Cheaper, Nano-Based Manufacturing: Scalable and cost-effective manufacturing of thin film devices February 14th, 2018

Academic/Education

Luleň University of Technology is using the Deben CT5000TEC stage to perform x-ray microtomography experiments with the ZEISS Xradia 510 Versa to understand deformation and strain inside inhomogeneous materials November 7th, 2017

Park Systems Announces the Grand Opening of the Park NanoScience Center at SUNY Polytechnic Institute November 3rd, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Moving at the Speed of Light: University of Arizona selected for high-impact, industrial demonstration of new integrated photonic cryogenic datalink for focal plane arrays: Program is major milestone for AIM Photonics August 10th, 2017

Nanomedicine

Arrowhead Receives Regulatory Clearance to Begin Phase 1/2 Study of ARO-HBV for Treatment of Hepatitis B February 15th, 2018

Arrowhead Pharmaceuticals Receives Orphan Drug Designation for ARO-AAT February 15th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Understanding brain functions using upconversion nanoparticles: Researchers can now send light deep into the brain to study neural activities February 14th, 2018

Announcements

Oxford Instruments announces Dr Kate Ross as winner of the 2018 Lee Osheroff Richardson Science Prize for North and South America February 20th, 2018

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

Nanobiotechnology

Arrowhead Receives Regulatory Clearance to Begin Phase 1/2 Study of ARO-HBV for Treatment of Hepatitis B February 15th, 2018

Arrowhead Pharmaceuticals Receives Orphan Drug Designation for ARO-AAT February 15th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Understanding brain functions using upconversion nanoparticles: Researchers can now send light deep into the brain to study neural activities February 14th, 2018

Research partnerships

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Rutgers-Led Innovation Could Spur Faster, Cheaper, Nano-Based Manufacturing: Scalable and cost-effective manufacturing of thin film devices February 14th, 2018

Understanding brain functions using upconversion nanoparticles: Researchers can now send light deep into the brain to study neural activities February 14th, 2018

Vanadium dioxyde: A revolutionary material for tomorrow's electronics: Phase-chance switch can now be performed at higher temperatures February 5th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project