Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Rheological technique predicts stability of SLNs

Dr. Uracha Ruktanonchai
Dr. Uracha Ruktanonchai

Abstract:
A rheological technique, used by researchers at National Nanotechnology Center (NANOTEC) in Thailand has revealed the instability of y-oryzanol-loaded solid lipid nanoparticles (SLNs) over 60 days storage at three different temperatures of 4, 25, and 40ºC.

Rheological technique predicts stability of SLNs

Thailand | Posted on August 24th, 2010

"Upon storage, gelation was developed in all samples, especially at 40ºC" said Dr. Uracha Ruktanonchai, Research Leader at Nano Delivery Lab, NANOTEC. "Rheological technique helps us in revealing this instability which is attributed by the increase in storage modulus, critical stress, and the characteristic relaxation time."

SLNs have gained interest as colloidal drug carriers due to their submicron size, potential for industrial production, and their physiological compositions. The carrier has been used for effective controlled-release and prolonged stability of both lipophilic and hydrophilic drugs. One of the lipophilic drugs found applications in cosmetic, pharmaceutical, and food areas is a natural antioxidant y-oryzanol, a main constituent in rice bran oil. Temperature and light exposure during storage have found to affect the stability of the nanoparticle.

The researchers reported their work in a paper published by Micron, the international research and review journal for microscopy. Collaborators on this investigation included National Metal and Materials Technology Center, National Science and Technology Development Agency, Thailand.

Dr. Uracha is currently exploring the fabrication of lipid nanoparticles and nanodispersion together with the characteristics of the resulting nanostructures particularly for medical and agricultural applications.

####

For more information, please click here

Contacts:
Media contact:
Ramjitti Indaraprasirt
Manager
International Relations Section
NANOTEC
02-564-7100 ext: 6617

Copyright © NANOTEC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Researchers discover new chemical sensing technique: Technique allows sharper detail -- and more information -- with near infrared light June 24th, 2016

Soft decoupling of organic molecules on metal June 23rd, 2016

Possible Futures

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Researchers discover new chemical sensing technique: Technique allows sharper detail -- and more information -- with near infrared light June 24th, 2016

GraphExeter illuminates bright new future for flexible lighting devices June 23rd, 2016

Soft decoupling of organic molecules on metal June 23rd, 2016

Academic/Education

JPK’s NanoWizard® AFM and ForceRobot® systems are being used in the field of medical diagnostics in the Supersensitive Molecular Layer Laboratory of POSTECH in Korea June 21st, 2016

Weizmann Institute of Science Presents: Weizmann Wonder Wander - 4G - is Online June 21st, 2016

NanoLabNL boosts quality of research facilities as Dutch Toekomstfonds invests firmly June 10th, 2016

The Institute for Transfusion Medicine at the University Hospital of Duisburg-Essen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles June 7th, 2016

Nanomedicine

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Self-assembling icosahedral protein designed: Self-assembling icosahedral protein designed June 22nd, 2016

Stealth nanocapsules kill Chagas parasites in mouse models June 22nd, 2016

Artificial synapse rivals biological ones in energy consumption June 21st, 2016

Announcements

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Researchers discover new chemical sensing technique: Technique allows sharper detail -- and more information -- with near infrared light June 24th, 2016

Soft decoupling of organic molecules on metal June 23rd, 2016

Nanobiotechnology

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Tailored DNA shifts electrons into the 'fast lane': DNA nanowire improved by altering sequences June 22nd, 2016

Self-assembling icosahedral protein designed: Self-assembling icosahedral protein designed June 22nd, 2016

Stealth nanocapsules kill Chagas parasites in mouse models June 22nd, 2016

Research partnerships

Soft decoupling of organic molecules on metal June 23rd, 2016

FEI and University of Liverpool Announce QEMSCAN Research Initiative: University of Liverpool will utilize FEI’s QEMSCAN technology to gain a better insight into oil and gas reserves & potentially change the approach to evaluating them June 22nd, 2016

Tailored DNA shifts electrons into the 'fast lane': DNA nanowire improved by altering sequences June 22nd, 2016

French Research Team Helps Extend MRI Detection of Diseases & Lower Health-Care Costs: CEA, INSERM and G2ELab Brings Grenoble Region’s Expertise In Advanced Medicine & Magnetism Applications to H2020 IDentIFY Project June 21st, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic