Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Nano firm teams with WFU to accelerate drug discovery

Abstract:
The Business Journal of the Greater Triad Area
By Matt Evans, Staff Writer

A New Jersey firm is relocating to the Triad to commercialize technology discovered at Wake Forest University. The technology could speed up the drug discovery process by as much as 10,000 times, according to company and university officials.

Nano firm teams with WFU to accelerate drug discovery

Winston-Salem, NC | Posted on August 10th, 2010

NanoMedica, Inc. has leased office space in the Piedmont Triad Research Park and signed a license option with Wake Forest for a technology called "Lab-on-Bead" that makes use of tiny beads to match drugs to disease markers.

The technology was developed by Jed Macosko, an associate professor of physics at Wake Forest who now also serves as NanoMedica's chief innovation officer. Co-inventor and fellow Wake Forest physics associate professor Martin Guthold is chief science officer; the company's chief technology officer is physics department Chairman Keith Bonin.

Macosko said that in the Lab-on-Bead process, nanoscopic plastic beads are studded with chemical "pins" that match up to a unique molecular "barcode" associated with a drug candidate.

The beads allow for rapid matching between the proteins specific to a particular disease and a drug showing characteristics that may act on that disease. The effect, Macosko said, is that the Lab-on-Bead process could screen 10,000 times more molecules in search of good drug candidates as current robotics-based methods.

"It does that by miniaturizing everything and putting essentially a whole laboratory onto a bead, instead of having to do each individual reaction in its own test tube," Macosko said.

A peer-reviewed paper on the technology will be published in the Journal of Molecular Recognition, and the Wake Forest inventors are working with NanoMedica CEO and founder Roger Cubicciotti to bring Lab-on-Bead to market. Cubicciotti founded NanoMedica in 2001 in New Jersey but has now relocated himself and the company to Winston-Salem.

The deal with Wake Forest gives NanoMedica one year to work with the technology to determine market feasibility before committing to a license. The company first began working with the university in 2003, Cubicciotti said.

The commercial vision for Lab-on-Bead is to "discover more with less," he said. The company initially would partner with companies that hold enormous libraries of potential drug candidates to offer molecules that other firms could then try to develop into drugs. Big pharma companies could also pay to apply the technology to their own molecular libraries to efficiently narrow down the list of those worth further development.

Starting small

NanoMedica is starting out as a small presence in Winston-Salem, with two technical employees so far besides its scientific principals. Cubicciotti said the company may have six employees by the first quarter of next year.

He moved his company because of its connection to Wake Forest but also because the state has done an excellent job supporting small companies like his that have the potential to grow, Cubicciotti said.

The N.C. Biotechnology Center, for example, provided $75,000 in funding for the research behind Lab-on-Bead.

"I've been extremely impressed by North Carolina's strategy in defining a unique signature at the crossroads of medicine and nanotechnology," he said. "It's impressive to see agencies focused not only on economic development, but also on attracting talent and fostering collaborations between companies and universities."

Cubicciotti singled out the Biotech Center's Center of Innovation for Nanobiotechnology for helping it navigate state resources and make introductions to other universities, including at N.C. A&T State University in Greensboro. The Center of Innovation for Nanobiotechnology, or Coin, was started as a joint project of N.C. A&T, UNC-Greensboro and Wake Forest to foster collaborations between industry and academics.

Brooks Adams, Coin's director, said his organization serves startups and companies like NanoMedica that are relocating to the area. He said he has invited Cubicciotti to join his board of directors.

"We're all about making resources in the state known to such people," Adams said. "There's no complete compendium available, so giving people a way to know about each other is a way to make things happen."

Adams said one of Coin's projects is to provide such a compendium online. A beta version of such a database is available now at the project's website, www.nc-coin.org.

NanoMedica Inc.
CEO: Roger Cubicciotti
Address: 101 N. Chestnut St.
Winston-Salem 27101
Phone: (336) 608-6010
Website: www.nanomedica.com

####

For more information, please click here

Contacts:
Bert Woodard
Next Level Communications (www.nextlevelcom.net)
For Piedmont Triad Partnership (www.piedmonttriadnc.com)
336-978-0021

Copyright © The Business Journal of the Greater Triad Area

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern July 21st, 2018

World's fastest man-made spinning object could help study quantum mechanics July 20th, 2018

Relax, just break it July 20th, 2018

Future electronic components to be printed like newspapers July 20th, 2018

Govt.-Legislation/Regulation/Funding/Policy

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern July 21st, 2018

World's fastest man-made spinning object could help study quantum mechanics July 20th, 2018

Relax, just break it July 20th, 2018

Future electronic components to be printed like newspapers July 20th, 2018

Possible Futures

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern July 21st, 2018

World's fastest man-made spinning object could help study quantum mechanics July 20th, 2018

Relax, just break it July 20th, 2018

Future electronic components to be printed like newspapers July 20th, 2018

Academic/Education

The Institute of Applied Physics at the University of Tsukuba near Tokyo in Japan uses Deben's ARM2 detector to better understand catalytic reaction mechanisms June 27th, 2018

Powering the 21st Century with Integrated Photonics: UCSB-Led Team Selected for Demonstration of a Novel Waveguide Platform Which is Transparent Throughout the MWIR and LWIR Spectral Bands June 19th, 2018

SUNY Poly Professor Eric Lifshin Selected for ‘Fellow of the Microanalysis Society’ Position for Significant Contributions to Microanalysis June 13th, 2018

Grand Opening of UC Irvine Materials Research Institute (IMRI) to Spotlight JEOL Center for Nanoscale Solutions: Renowned Materials Scientists to Present at the 1st International Symposium on Advanced Microscopy and Spectroscopy (ISAMS) April 18th, 2018

Nanomedicine

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Researchers identify cost-cutting option in treating nail fungus with nanotechnology: GW researcher Adam Friedman, M.D., studied the potential use of nitric oxide-releasing nanoparticles to improve onychomycosis treatment July 11th, 2018

New sensor technology enables super-sensitive live monitoring of human biomolecules July 3rd, 2018

Announcements

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern July 21st, 2018

World's fastest man-made spinning object could help study quantum mechanics July 20th, 2018

Relax, just break it July 20th, 2018

Future electronic components to be printed like newspapers July 20th, 2018

Nanobiotechnology

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Researchers identify cost-cutting option in treating nail fungus with nanotechnology: GW researcher Adam Friedman, M.D., studied the potential use of nitric oxide-releasing nanoparticles to improve onychomycosis treatment July 11th, 2018

New sensor technology enables super-sensitive live monitoring of human biomolecules July 3rd, 2018

Arrowhead Presents New Clinical Data on ARO-AAT at Alpha-1 National Education Conference July 1st, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project