Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Nano firm teams with WFU to accelerate drug discovery

Abstract:
The Business Journal of the Greater Triad Area
By Matt Evans, Staff Writer

A New Jersey firm is relocating to the Triad to commercialize technology discovered at Wake Forest University. The technology could speed up the drug discovery process by as much as 10,000 times, according to company and university officials.

Nano firm teams with WFU to accelerate drug discovery

Winston-Salem, NC | Posted on August 10th, 2010

NanoMedica, Inc. has leased office space in the Piedmont Triad Research Park and signed a license option with Wake Forest for a technology called "Lab-on-Bead" that makes use of tiny beads to match drugs to disease markers.

The technology was developed by Jed Macosko, an associate professor of physics at Wake Forest who now also serves as NanoMedica's chief innovation officer. Co-inventor and fellow Wake Forest physics associate professor Martin Guthold is chief science officer; the company's chief technology officer is physics department Chairman Keith Bonin.

Macosko said that in the Lab-on-Bead process, nanoscopic plastic beads are studded with chemical "pins" that match up to a unique molecular "barcode" associated with a drug candidate.

The beads allow for rapid matching between the proteins specific to a particular disease and a drug showing characteristics that may act on that disease. The effect, Macosko said, is that the Lab-on-Bead process could screen 10,000 times more molecules in search of good drug candidates as current robotics-based methods.

"It does that by miniaturizing everything and putting essentially a whole laboratory onto a bead, instead of having to do each individual reaction in its own test tube," Macosko said.

A peer-reviewed paper on the technology will be published in the Journal of Molecular Recognition, and the Wake Forest inventors are working with NanoMedica CEO and founder Roger Cubicciotti to bring Lab-on-Bead to market. Cubicciotti founded NanoMedica in 2001 in New Jersey but has now relocated himself and the company to Winston-Salem.

The deal with Wake Forest gives NanoMedica one year to work with the technology to determine market feasibility before committing to a license. The company first began working with the university in 2003, Cubicciotti said.

The commercial vision for Lab-on-Bead is to "discover more with less," he said. The company initially would partner with companies that hold enormous libraries of potential drug candidates to offer molecules that other firms could then try to develop into drugs. Big pharma companies could also pay to apply the technology to their own molecular libraries to efficiently narrow down the list of those worth further development.

Starting small

NanoMedica is starting out as a small presence in Winston-Salem, with two technical employees so far besides its scientific principals. Cubicciotti said the company may have six employees by the first quarter of next year.

He moved his company because of its connection to Wake Forest but also because the state has done an excellent job supporting small companies like his that have the potential to grow, Cubicciotti said.

The N.C. Biotechnology Center, for example, provided $75,000 in funding for the research behind Lab-on-Bead.

"I've been extremely impressed by North Carolina's strategy in defining a unique signature at the crossroads of medicine and nanotechnology," he said. "It's impressive to see agencies focused not only on economic development, but also on attracting talent and fostering collaborations between companies and universities."

Cubicciotti singled out the Biotech Center's Center of Innovation for Nanobiotechnology for helping it navigate state resources and make introductions to other universities, including at N.C. A&T State University in Greensboro. The Center of Innovation for Nanobiotechnology, or Coin, was started as a joint project of N.C. A&T, UNC-Greensboro and Wake Forest to foster collaborations between industry and academics.

Brooks Adams, Coin's director, said his organization serves startups and companies like NanoMedica that are relocating to the area. He said he has invited Cubicciotti to join his board of directors.

"We're all about making resources in the state known to such people," Adams said. "There's no complete compendium available, so giving people a way to know about each other is a way to make things happen."

Adams said one of Coin's projects is to provide such a compendium online. A beta version of such a database is available now at the project's website, www.nc-coin.org.

NanoMedica Inc.
CEO: Roger Cubicciotti
Address: 101 N. Chestnut St.
Winston-Salem 27101
Phone: (336) 608-6010
Website: www.nanomedica.com

####

For more information, please click here

Contacts:
Bert Woodard
Next Level Communications (www.nextlevelcom.net)
For Piedmont Triad Partnership (www.piedmonttriadnc.com)
336-978-0021

Copyright © The Business Journal of the Greater Triad Area

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanostructures Increase Corrosion Resistance in Metallic Body Implants May 24th, 2015

Iranian Scientists Use Magnetic Field to Transfer Anticancer Drug to Tumor Tissue May 24th, 2015

Basel physicists develop efficient method of signal transmission from nanocomponents May 23rd, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Govt.-Legislation/Regulation/Funding/Policy

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Visualizing How Radiation Bombardment Boosts Superconductivity: Atomic-level flyovers show how impact sites of high-energy ions pin potentially disruptive vortices to keep high-current superconductivity flowing May 23rd, 2015

Nanotherapy effective in mice with multiple myeloma May 21st, 2015

Turn that defect upside down: Twin boundaries in lithium-ion batteries May 21st, 2015

Possible Futures

Simulations predict flat liquid May 21st, 2015

Nature inspires first artificial molecular pump: Simple design mimics pumping mechanism of life-sustaining proteins found in living cells May 19th, 2015

NNCO and Museum of Science Fiction to Collaborate on Nanotechnology and 3D Printing Panels at Awesome Con May 19th, 2015

Quantum 'gruyres' for spintronics of the future: Topological insulators become a little less 'elusive' May 12th, 2015

Academic/Education

SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium: May 20th, 2015

New JEOL E-Beam Lithography System to Enhance Quantum NanoFab Capabilities May 6th, 2015

FEI Partners With the George Washington University to Equip New Science & Engineering Hall: Suite of new high-performance microscopes will be used for cutting-edge experiments at GWs new research facility April 29th, 2015

Renishaw Raman systems used to study 2D materials at Boston University, Massachusetts, USA. April 28th, 2015

Nanomedicine

Nanostructures Increase Corrosion Resistance in Metallic Body Implants May 24th, 2015

Iranian Scientists Use Magnetic Field to Transfer Anticancer Drug to Tumor Tissue May 24th, 2015

New Antibacterial Wound Dressing in Iran Can Display Replacement Time May 22nd, 2015

Researchers develop new way to manufacture nanofibers May 21st, 2015

Announcements

Nanostructures Increase Corrosion Resistance in Metallic Body Implants May 24th, 2015

Iranian Scientists Use Magnetic Field to Transfer Anticancer Drug to Tumor Tissue May 24th, 2015

Basel physicists develop efficient method of signal transmission from nanocomponents May 23rd, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Nanobiotechnology

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Supercomputer unlocks secrets of plant cells to pave the way for more resilient crops: IBM partners with University of Melbourne and UQ May 21st, 2015

Researchers develop new way to manufacture nanofibers May 21st, 2015

Nature inspires first artificial molecular pump: Simple design mimics pumping mechanism of life-sustaining proteins found in living cells May 19th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project