Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Nano firm teams with WFU to accelerate drug discovery

Abstract:
The Business Journal of the Greater Triad Area
By Matt Evans, Staff Writer

A New Jersey firm is relocating to the Triad to commercialize technology discovered at Wake Forest University. The technology could speed up the drug discovery process by as much as 10,000 times, according to company and university officials.

Nano firm teams with WFU to accelerate drug discovery

Winston-Salem, NC | Posted on August 10th, 2010

NanoMedica, Inc. has leased office space in the Piedmont Triad Research Park and signed a license option with Wake Forest for a technology called "Lab-on-Bead" that makes use of tiny beads to match drugs to disease markers.

The technology was developed by Jed Macosko, an associate professor of physics at Wake Forest who now also serves as NanoMedica's chief innovation officer. Co-inventor and fellow Wake Forest physics associate professor Martin Guthold is chief science officer; the company's chief technology officer is physics department Chairman Keith Bonin.

Macosko said that in the Lab-on-Bead process, nanoscopic plastic beads are studded with chemical "pins" that match up to a unique molecular "barcode" associated with a drug candidate.

The beads allow for rapid matching between the proteins specific to a particular disease and a drug showing characteristics that may act on that disease. The effect, Macosko said, is that the Lab-on-Bead process could screen 10,000 times more molecules in search of good drug candidates as current robotics-based methods.

"It does that by miniaturizing everything and putting essentially a whole laboratory onto a bead, instead of having to do each individual reaction in its own test tube," Macosko said.

A peer-reviewed paper on the technology will be published in the Journal of Molecular Recognition, and the Wake Forest inventors are working with NanoMedica CEO and founder Roger Cubicciotti to bring Lab-on-Bead to market. Cubicciotti founded NanoMedica in 2001 in New Jersey but has now relocated himself and the company to Winston-Salem.

The deal with Wake Forest gives NanoMedica one year to work with the technology to determine market feasibility before committing to a license. The company first began working with the university in 2003, Cubicciotti said.

The commercial vision for Lab-on-Bead is to "discover more with less," he said. The company initially would partner with companies that hold enormous libraries of potential drug candidates to offer molecules that other firms could then try to develop into drugs. Big pharma companies could also pay to apply the technology to their own molecular libraries to efficiently narrow down the list of those worth further development.

Starting small

NanoMedica is starting out as a small presence in Winston-Salem, with two technical employees so far besides its scientific principals. Cubicciotti said the company may have six employees by the first quarter of next year.

He moved his company because of its connection to Wake Forest but also because the state has done an excellent job supporting small companies like his that have the potential to grow, Cubicciotti said.

The N.C. Biotechnology Center, for example, provided $75,000 in funding for the research behind Lab-on-Bead.

"I've been extremely impressed by North Carolina's strategy in defining a unique signature at the crossroads of medicine and nanotechnology," he said. "It's impressive to see agencies focused not only on economic development, but also on attracting talent and fostering collaborations between companies and universities."

Cubicciotti singled out the Biotech Center's Center of Innovation for Nanobiotechnology for helping it navigate state resources and make introductions to other universities, including at N.C. A&T State University in Greensboro. The Center of Innovation for Nanobiotechnology, or Coin, was started as a joint project of N.C. A&T, UNC-Greensboro and Wake Forest to foster collaborations between industry and academics.

Brooks Adams, Coin's director, said his organization serves startups and companies like NanoMedica that are relocating to the area. He said he has invited Cubicciotti to join his board of directors.

"We're all about making resources in the state known to such people," Adams said. "There's no complete compendium available, so giving people a way to know about each other is a way to make things happen."

Adams said one of Coin's projects is to provide such a compendium online. A beta version of such a database is available now at the project's website, www.nc-coin.org.

NanoMedica Inc.
CEO: Roger Cubicciotti
Address: 101 N. Chestnut St.
Winston-Salem 27101
Phone: (336) 608-6010
Website: www.nanomedica.com

####

For more information, please click here

Contacts:
Bert Woodard
Next Level Communications (www.nextlevelcom.net)
For Piedmont Triad Partnership (www.piedmonttriadnc.com)
336-978-0021

Copyright © The Business Journal of the Greater Triad Area

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Protein Building Blocks for Nanosystems: Scientists develop method for producing bio-based materials with new properties April 17th, 2015

Oxford Instruments commissions high field outsert magnet system for the National High Magnetic Field Laboratory 32 Tesla magnet program April 17th, 2015

QD Vision Expands Product Line with Two-Millimeter Color LCD Display Optic: Color IQ™ Optic Enables Full-Color Gamut for Ultra-Thin Displays and All-in-One Computers April 16th, 2015

The National Science Foundation names engineering researcher Andrea Alú its Alan T. Waterman awardee for 2015: Alú is a pioneer in the field of metamaterials who has developed "cloaking" technology to make objects invisible to sensors April 16th, 2015

Govt.-Legislation/Regulation/Funding/Policy

Oxford Instruments commissions high field outsert magnet system for the National High Magnetic Field Laboratory 32 Tesla magnet program April 17th, 2015

The National Science Foundation names engineering researcher Andrea Alú its Alan T. Waterman awardee for 2015: Alú is a pioneer in the field of metamaterials who has developed "cloaking" technology to make objects invisible to sensors April 16th, 2015

Long Island Capital Alliance Announces Participants for Brookhaven National Laboratory Technology Transfer Capital Forum on May 8: Keynote Speaker Dr. Doon Gibbs, Director of Brookhaven National Laboratory April 16th, 2015

Major advance in artificial photosynthesis poses win/win for the environment: Berkeley Lab researchers perform solar-powered green chemistry with captured CO2 April 16th, 2015

Possible Futures

A glass fiber that brings light to a standstill: By coupling photons to atoms, light in a glass fiber can be slowed down to the speed of an express train; for a short while it can even be brought to a complete stop April 9th, 2015

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Nanotechnology Enabled Drug Delivery to Influence Future Diagnosis and Treatments of Diseases March 21st, 2015

Nanocomposites Market Growth, Industry Outlook To 2020 by Grand View Research, Inc. March 21st, 2015

Academic/Education

JPK reports on the use of the NanoWizard® 3 AFM system at the Hebrew University of Jerusalem April 14th, 2015

UK National Graphene Institute Selects Bruker as Official Partner: World-Leading Graphene Research Facility Purchases Multiple Bruker AFMs April 7th, 2015

SUNY Poly CNSE and Title Sponsor SEFCU Name Capital Region Teams Advancing to the Final Round of the 2015 New York Business Plan Competition March 30th, 2015

LAMDAMAP 2015 hosted by the University March 26th, 2015

Nanomedicine

Novel nanoparticles could save soldiers' lives after explosions April 15th, 2015

Nanoparticles at specific temperature stimulate antitumor response: Dartmouth researchers identify precise heat to boost immune system against cancer tumors April 14th, 2015

Iranian Scientists Evaluate Dynamic Interaction between 2 Carbon Nanotubes April 14th, 2015

Gold by special delivery intensifies cancer-killing radiation April 13th, 2015

Announcements

Protein Building Blocks for Nanosystems: Scientists develop method for producing bio-based materials with new properties April 17th, 2015

Oxford Instruments commissions high field outsert magnet system for the National High Magnetic Field Laboratory 32 Tesla magnet program April 17th, 2015

Newly-Developed Nanocatalysts Increase Performance of Fuel Cells April 16th, 2015

Lanthanide-Organic Framework Nanothermometers Prepared by Spray-Drying April 16th, 2015

Nanobiotechnology

Protein Building Blocks for Nanosystems: Scientists develop method for producing bio-based materials with new properties April 17th, 2015

Study shows novel pattern of electrical charge movement through DNA April 14th, 2015

UAB researchers develop a harmless artificial virus for gene therapy April 8th, 2015

Pavel Levkin Is Granted Heinz Maier-Leibnitz Prize April 8th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE