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August 2nd, 2010
Growing Organs and Helping Wounds Heal
Abstract:
A stretchy new fabric made by linking together the proteins found in muscle tissue could provide a scaffold for growing new organs. It could also be used as a coating for bandages to help wounds heal quickly and with less scarring. The fabric was made in the laboratory of Kevin Kit Parker, a professor at Harvard's School of Engineering and Applied Science.
Parker's team creates the fabric by depositing fibronectin molecules on top of a water-repelling polymer surface. This causes the proteins, which are normally bundled up, to unravel. Next, the protein layer is stamped onto a dissolvable, water-attracting polymer sheet on top of a piece of glass. Adding water and warming the mixture to room temperature makes the proteins link together to form the fabric. It also dissolves the polymer so that the fabric can be peeled away and collected.
The team made swatches of material 10 nanometers thick and about 2.5 centimeters wide. The researchers can control the architecture and mechanical characteristics of the fabric by using different proteins, or changing the way they are aligned.
Source:
technologyreview.com
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