Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > UQ researchers develop a dissolvable needle-free Nanopatch for vaccine delivery

Professor Mark Kendall
Professor Mark Kendall

Abstract:
AIBN research has found the Nanopatch - a needle-free, pain-free method of vaccine delivery - is now dissolvable, eliminating the possibility of needle-stick injury.

UQ researchers develop a dissolvable needle-free Nanopatch for vaccine delivery

Australia | Posted on July 26th, 2010

Project leader Professor Mark Kendall said the finding confirmed that the Nanopatch was a potential safer, cheaper alternative to needle vaccines.

The study was published recently in scientific journal Small.

"What we have been able to show for the first time is that the Nanopatch is completely dissolvable," Professor Kendall said.

"That means zero needles, zero sharps, zero opportunity for contamination and zero chance of needle-stick injury.

"The World Health Organisation estimates that 30 percent of vaccinations in Africa are unsafe due to cross contamination caused by needle-stick injury. That's a healthcare burden of about $25 per administration."

The Nanopatch is smaller than a postage stamp and is packed with thousands of tiny projections - invisible to the human eye - now dried to include the vaccine itself together with biocompatible excipients.

When the patch is placed against the skin, these projections push through the outer skin layer and deliver the biomolecules to the target cells.

When dry, the device is stable and strong. When the Nanopatch is applied to the skin, the projections immediately become wet, dissolving within minutes.

Research published in journal Plos One in April found that the Nanopatch achieved a protective immune response using an unprecedented one-hundredth of the standard needle and syringe dose.

Professor Kendall said this was 10 times better than any other delivery method.

Being both painless and needle-free, the Nanopatch offers hope for those with needle phobia, as well as improving the vaccination experience for young children.

"When compared to a needle and syringe, a Nanopatch is cheap to produce and it is easy to imagine a situation in which a Government might provide vaccinations for a pandemic such as swine flu to be collected from a chemist or sent in the mail," Professor Kendall said.

He said the work had been in progress for five years and his team hoped to start clinical trials soon.

The study was conducted using influenza vaccine but Professor Kendall said any vaccine could potentially be delivered via the Nanopatch.

Also published in a separate paper in Small is research showing the Nanopatch's success extends to candidate vaccines for West Nile virus and Chukunga virus.

Professor Kendall is based at both UQ's Australian Institute for Bioengineering and Nanotechnology and the Diamantina Institute.

His collaborators for this work include Professor Ian Frazer and researchers from the University of Melbourne.

####

For more information, please click here

Contacts:
Media:
Professor Kendall
0431 162 391)

Penny Robinson
UQ Communications
07 3365 9723


Copyright © Australian Institute for Bioengineering and Nanotechnology

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Getting electrons to move in a semiconductor: Gallium oxide shows high electron mobility, making it promising for better and cheaper devices April 24th, 2018

JPK reports on research of the Mestroni Lab at the University of Colorado Denver which use the JPK NanoWizard® AFM to help in the characterization of cardiomyopathies April 24th, 2018

Organic solar cells reach record efficiency, benchmark for commercialization April 23rd, 2018

Remote-control shoots laser at nano-gold to turn on cancer-killing immune cells April 20th, 2018

Possible Futures

Getting electrons to move in a semiconductor: Gallium oxide shows high electron mobility, making it promising for better and cheaper devices April 24th, 2018

JPK reports on research of the Mestroni Lab at the University of Colorado Denver which use the JPK NanoWizard® AFM to help in the characterization of cardiomyopathies April 24th, 2018

Organic solar cells reach record efficiency, benchmark for commercialization April 23rd, 2018

Remote-control shoots laser at nano-gold to turn on cancer-killing immune cells April 20th, 2018

Academic/Education

Grand Opening of UC Irvine Materials Research Institute (IMRI) to Spotlight JEOL Center for Nanoscale Solutions: Renowned Materials Scientists to Present at the 1st International Symposium on Advanced Microscopy and Spectroscopy (ISAMS) April 18th, 2018

Lifeboat Foundation funds flying 3D-printed classroom cubesats with Perlan II April 16th, 2018

SUNY Poly’s Center for Semiconductor Research in Albany Earns World-Class TÜV SÜD AMERICA INC. ISO 9001:2015 Certification: Albany NanoTech Complex Certification Assures Top-Tier Quality in Semiconductor Test Structures; Certification a First for a SUNY Campus March 6th, 2018

Luleå University of Technology is using the Deben CT5000TEC stage to perform x-ray microtomography experiments with the ZEISS Xradia 510 Versa to understand deformation and strain inside inhomogeneous materials November 7th, 2017

Nanomedicine

JPK reports on research of the Mestroni Lab at the University of Colorado Denver which use the JPK NanoWizard® AFM to help in the characterization of cardiomyopathies April 24th, 2018

Remote-control shoots laser at nano-gold to turn on cancer-killing immune cells April 20th, 2018

Observing biological nanotransporters: Chemistry April 19th, 2018

Nanobiotix Shows NBTXR3 Nanoparticles Can Stoke Anti-Tumor Immune Response April 17th, 2018

Announcements

Getting electrons to move in a semiconductor: Gallium oxide shows high electron mobility, making it promising for better and cheaper devices April 24th, 2018

JPK reports on research of the Mestroni Lab at the University of Colorado Denver which use the JPK NanoWizard® AFM to help in the characterization of cardiomyopathies April 24th, 2018

Organic solar cells reach record efficiency, benchmark for commercialization April 23rd, 2018

Remote-control shoots laser at nano-gold to turn on cancer-killing immune cells April 20th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project