Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > UQ researchers develop a dissolvable needle-free Nanopatch for vaccine delivery

Professor Mark Kendall
Professor Mark Kendall

Abstract:
AIBN research has found the Nanopatch - a needle-free, pain-free method of vaccine delivery - is now dissolvable, eliminating the possibility of needle-stick injury.

UQ researchers develop a dissolvable needle-free Nanopatch for vaccine delivery

Australia | Posted on July 26th, 2010

Project leader Professor Mark Kendall said the finding confirmed that the Nanopatch was a potential safer, cheaper alternative to needle vaccines.

The study was published recently in scientific journal Small.

"What we have been able to show for the first time is that the Nanopatch is completely dissolvable," Professor Kendall said.

"That means zero needles, zero sharps, zero opportunity for contamination and zero chance of needle-stick injury.

"The World Health Organisation estimates that 30 percent of vaccinations in Africa are unsafe due to cross contamination caused by needle-stick injury. That's a healthcare burden of about $25 per administration."

The Nanopatch is smaller than a postage stamp and is packed with thousands of tiny projections - invisible to the human eye - now dried to include the vaccine itself together with biocompatible excipients.

When the patch is placed against the skin, these projections push through the outer skin layer and deliver the biomolecules to the target cells.

When dry, the device is stable and strong. When the Nanopatch is applied to the skin, the projections immediately become wet, dissolving within minutes.

Research published in journal Plos One in April found that the Nanopatch achieved a protective immune response using an unprecedented one-hundredth of the standard needle and syringe dose.

Professor Kendall said this was 10 times better than any other delivery method.

Being both painless and needle-free, the Nanopatch offers hope for those with needle phobia, as well as improving the vaccination experience for young children.

"When compared to a needle and syringe, a Nanopatch is cheap to produce and it is easy to imagine a situation in which a Government might provide vaccinations for a pandemic such as swine flu to be collected from a chemist or sent in the mail," Professor Kendall said.

He said the work had been in progress for five years and his team hoped to start clinical trials soon.

The study was conducted using influenza vaccine but Professor Kendall said any vaccine could potentially be delivered via the Nanopatch.

Also published in a separate paper in Small is research showing the Nanopatch's success extends to candidate vaccines for West Nile virus and Chukunga virus.

Professor Kendall is based at both UQ's Australian Institute for Bioengineering and Nanotechnology and the Diamantina Institute.

His collaborators for this work include Professor Ian Frazer and researchers from the University of Melbourne.

####

For more information, please click here

Contacts:
Media:
Professor Kendall
0431 162 391)

Penny Robinson
UQ Communications
07 3365 9723


Copyright © Australian Institute for Bioengineering and Nanotechnology

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

Stretchy supercapacitors power wearable electronics August 25th, 2016

Possible Futures

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

Nanofiber scaffolds demonstrate new features in the behavior of stem and cancer cells August 25th, 2016

Nanofur for oil spill cleanup: Materials researchers learn from aquatic ferns: Hairy plant leaves are highly oil-absorbing / publication in bioinspiration & biomimetics / video on absorption capacity August 25th, 2016

Academic/Education

AIM Photonics Announces Release of Process Design Kit (PDK) for Integrated Silicon Photonics Design August 25th, 2016

Nanotech Security Featured by Simon Fraser University: Company's Anti-Counterfeiting Technology Developed With the Help of University's 4D LABS Materials Research Institute August 21st, 2016

W.M. Keck Foundation awards Cal State LA a $375,000 research and education grant August 4th, 2016

Thomas Swan and NGI announce unique partnership July 28th, 2016

Nanomedicine

Nanofiber scaffolds demonstrate new features in the behavior of stem and cancer cells August 25th, 2016

Johns Hopkins scientists track metabolic pathways to find drug combination for pancreatic cancer August 25th, 2016

50 years after the release of the film 'Fantastic Voyage,' science upstages fiction: Science upstages fiction with nanorobotic agents designed to travel in the human body to treat cancer August 25th, 2016

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes August 24th, 2016

Announcements

Forces of nature: Interview with microscopy innovators Gerd Binnig and Christoph Gerber August 26th, 2016

A promising route to the scalable production of highly crystalline graphene films August 26th, 2016

Graphene under pressure August 26th, 2016

New electrical energy storage material shows its power: Nanomaterial combines attributes of both batteries and supercapacitors August 25th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic