Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button

Home > Press > Thai researchers investigate prospects of nanoparticles as drug delivery

Abstract:
Thai researchers investigate prospects of nanoparticles as drug delivery system

Thai researchers investigate prospects of nanoparticles as drug delivery

Bangkok | Posted on June 28th, 2010

Researchers at Thailand's National Nanotechnology Center (NANOTEC), Nano-delivery System Laboratory are investigating the chemical and structural of gamma-oryzanol, a model drug, loaded inside a model lipid nanoparticles drug-delivery system. The delivery system composed of cetyl palmitate as solid lipid, and Miglyol 812 as liquid lipid.

In a recent raman mapping study, which was published in February 2010 by Nanotechnology, the authors demonstrated a bottom-up approach for the fabrication of lipid nanoparticles utilizing a high pressure homogenization at varying liquid lipid contents. Lipid nanoparticles have been selected as a model system due to its promising alternative to existing carriers in drug delivery systems. "A key challenge in this study was to determine precisely how chemicals are incorporated and distributed inside nanoparticles, which assists in controlling chemical retention and release characteristics" said Dr Uracha Raktanonchai, Head of NANOTEC Nano-delivery System Lab.

Raman mapping technique has been proven as an efficient method to investigate drug and lipid molecular distribution at nanoscale level. This investigation elaborates that liquid lipid loading in lipid nanoparticles plays a major role in improving the drug distribution and solubility in lipid nanoparticles.

"These findings provide useful implications for future designs of nanoparticles as drug delivery systems" said Dr Uracha. Collaborators on this investigation included the Department of Chemistry, Faculty of Science, Mahidol University, and College of KMITL Nanotechnology, King Mongkut's Institute of Technology Ladkrabang, Thailand.

Dr Uracha is currently exploring the fabrication of lipid nanoparticles and nanodispersion together with the characteristics of the resulting nanostructures particularly for medical and agricultural applications.

####

About NANOTEC
To promote, support and perform research and development on nanotechnology, through in-house research laboratories and partners in universities, other research agencies and industry, aiming at the applications of nanotechnology for innovative enhancement of Thai products, and for strengthening Thailand’s competitive position in the world market.

For more information, please click here

Contacts:
Ramjitti Indaraprasirt

Copyright © NANOTEC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New microchip demonstrates efficiency and scalable design: Increased power and slashed energy consumption for data centers August 24th, 2016

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes August 24th, 2016

New flexible material can make any window 'smart' August 23rd, 2016

University of Puerto Rico and NASA back in the news – XEI reports August 23rd, 2016

Nanomedicine

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes August 24th, 2016

Nanoparticles that speed blood clotting may someday save lives August 23rd, 2016

A new way to display the 3-D structure of molecules: Metal-organic frameworks provide a new platform for solving the structure of hard-to-study samples August 21st, 2016

Curbing the life-long effects of traumatic brain injury August 19th, 2016

Announcements

New microchip demonstrates efficiency and scalable design: Increased power and slashed energy consumption for data centers August 24th, 2016

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes August 24th, 2016

New flexible material can make any window 'smart' August 23rd, 2016

University of Puerto Rico and NASA back in the news – XEI reports August 23rd, 2016

Nanobiotechnology

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes August 24th, 2016

Nanoparticles that speed blood clotting may someday save lives August 23rd, 2016

A new way to display the 3-D structure of molecules: Metal-organic frameworks provide a new platform for solving the structure of hard-to-study samples August 21st, 2016

Curbing the life-long effects of traumatic brain injury August 19th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic