Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Less is more! Nanopatch is 100 times better than needle and syringe

Professor Kendall
Professor Kendall

Abstract:
New research, led by Professor Mark Kendall, from UQ's Australian Institute for Bioengineering and Nanotechnology, demonstrates that a vaccine delivered by a Nanopatch induces a similarly protective immune response as a vaccine delivered by needle and syringe, but uses 100 times less vaccine.

Less is more! Nanopatch is 100 times better than needle and syringe

Brisbane, Australia | Posted on April 22nd, 2010

This discovery has implications for many vaccination programs in both industrialised and developing nations, which must overcome issues with vaccine shortages and distribution.

Being both painless and needle-free, the nanopatch offers hope for those with needle phobia, as well as improving the vaccination experience for young children.

"The Nanopatch targeted specific antigen-presenting cells found in a narrow layer just beneath the skin surface and as a result we used less than one hundredth of the dose used by a needle while stimulating a comparable immune response," Professor Kendall said.

"Our result is ten times better than the best results achieved by other delivery methods and does not require the use of other immune stimulants, called adjuvants, or multiple vaccinations.

"Because the Nanopatch requires neither a trained practitioner to administer it nor refrigeration, it has enormous potential cheaply deliver vaccines in developing nations," he said.

Professor Kendall said the Nanopatch� was much smaller than a postage stamp and comprised of several thousands of densely packed projections invisible to the human eye.

The influenza vaccine was dry coated onto these projections and applied to the skin of mice for two minutes. "By using far less vaccine we believe that the Nanopatch will enable the vaccination of many more people," Professor Kendall said.

"When compared to a needle and syringe a nanopatch is cheap to produce and it is easy to imagine a situation in which a government might provide vaccinations for a pandemic such as swine flu to be collected from a chemist or sent in the mail.

"This is an exciting discovery and our next step is to prove the effectiveness of Nanopatches in human clinical trials," he said.

Professor Kendall's team includes researchers from UQ's Diamantina Institute for Cancer, Immunology and Metabolic Medicine and Faculty of Health Sciences, as well as the University of Melbourne.

The work was supported by the Australian Research Council, the National Health and Medical Research Council, and the Queensland Government's Smart State Scheme.

AIBN is a multidisciplinary research institute focused on addressing some of the intricate problems in the areas of health, energy and the environment.

####

For more information, please click here

Contacts:
Media:
Professor Mark Kendall
07 3346 4203 or 0431 162 391

Copyright © University of Queensland

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Particle Works creates range of high performance quantum dots February 23rd, 2017

GLOBALFOUNDRIES Announces Availability of 45nm RF SOI to Advance 5G Mobile Communications: Optimized RF features deliver high-performance solutions for mmWave beam forming applications in 5G smartphones and base stations February 22nd, 2017

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

JPK selects compact tensile stage from Deben for their NanoWizard® AFM platform to broaden capabilities for materials characterisation February 22nd, 2017

Possible Futures

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

Tiny nanoclusters could solve big problems for lithium-ion batteries February 21st, 2017

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Breakthrough with a chain of gold atoms: In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport February 20th, 2017

Academic/Education

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Oxford Nanoimaging report on how the Nanoimager, a desktop microscope delivering single molecule, super-resolution performance, is being applied at the MRC Centre for Molecular Bacteriology & Infection November 22nd, 2016

The University of Applied Sciences in Upper Austria uses Deben tensile stages as an integral part of their computed tomography research and testing facility October 18th, 2016

Enterprise In Space Partners with Sketchfab and 3D Hubs for NewSpace Education October 13th, 2016

Nanomedicine

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Announcements

Particle Works creates range of high performance quantum dots February 23rd, 2017

GLOBALFOUNDRIES Announces Availability of 45nm RF SOI to Advance 5G Mobile Communications: Optimized RF features deliver high-performance solutions for mmWave beam forming applications in 5G smartphones and base stations February 22nd, 2017

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

JPK selects compact tensile stage from Deben for their NanoWizard® AFM platform to broaden capabilities for materials characterisation February 22nd, 2017

Nanobiotechnology

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Nanobiotix appoints senior executive from pharmaceutical industry, as Chief Operating Officer: Oncology industry veteran to oversee operations and product commercialization February 8th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project