Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Less is more! Nanopatch is 100 times better than needle and syringe

Professor Kendall
Professor Kendall

Abstract:
New research, led by Professor Mark Kendall, from UQ's Australian Institute for Bioengineering and Nanotechnology, demonstrates that a vaccine delivered by a Nanopatch induces a similarly protective immune response as a vaccine delivered by needle and syringe, but uses 100 times less vaccine.

Less is more! Nanopatch is 100 times better than needle and syringe

Brisbane, Australia | Posted on April 22nd, 2010

This discovery has implications for many vaccination programs in both industrialised and developing nations, which must overcome issues with vaccine shortages and distribution.

Being both painless and needle-free, the nanopatch offers hope for those with needle phobia, as well as improving the vaccination experience for young children.

"The Nanopatch targeted specific antigen-presenting cells found in a narrow layer just beneath the skin surface and as a result we used less than one hundredth of the dose used by a needle while stimulating a comparable immune response," Professor Kendall said.

"Our result is ten times better than the best results achieved by other delivery methods and does not require the use of other immune stimulants, called adjuvants, or multiple vaccinations.

"Because the Nanopatch requires neither a trained practitioner to administer it nor refrigeration, it has enormous potential cheaply deliver vaccines in developing nations," he said.

Professor Kendall said the Nanopatch� was much smaller than a postage stamp and comprised of several thousands of densely packed projections invisible to the human eye.

The influenza vaccine was dry coated onto these projections and applied to the skin of mice for two minutes. "By using far less vaccine we believe that the Nanopatch will enable the vaccination of many more people," Professor Kendall said.

"When compared to a needle and syringe a nanopatch is cheap to produce and it is easy to imagine a situation in which a government might provide vaccinations for a pandemic such as swine flu to be collected from a chemist or sent in the mail.

"This is an exciting discovery and our next step is to prove the effectiveness of Nanopatches in human clinical trials," he said.

Professor Kendall's team includes researchers from UQ's Diamantina Institute for Cancer, Immunology and Metabolic Medicine and Faculty of Health Sciences, as well as the University of Melbourne.

The work was supported by the Australian Research Council, the National Health and Medical Research Council, and the Queensland Government's Smart State Scheme.

AIBN is a multidisciplinary research institute focused on addressing some of the intricate problems in the areas of health, energy and the environment.

####

For more information, please click here

Contacts:
Media:
Professor Mark Kendall
07 3346 4203 or 0431 162 391

Copyright © University of Queensland

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoparticle reduces targeted cancer drug's toxicity February 11th, 2016

Cima NanoTech Debuts Large Interactive Touch Screens with European Customers at ISE 2016: For the first time in Europe, Cima NanoTech’s wide range of high performance, projected capacitive touch modules are showcased February 11th, 2016

Scientists take nanoparticle snapshots February 10th, 2016

Chemical cages: New technique advances synthetic biology February 10th, 2016

Possible Futures

Chemical cages: New technique advances synthetic biology February 10th, 2016

New thin film transistor may lead to flexible devices: Researchers engineer an electronics first, opening door to flexible electronics February 10th, 2016

Electron's 1-D metallic surface state observed: A step for the prediction of electronic properties of extremely-fine metal nanowires in next-generation semiconductors February 9th, 2016

A fast solidification process makes material crackle February 8th, 2016

Academic/Education

SUNY Poly and GLOBALFOUNDRIES Announce New $500M R&D Program in Albany To Accelerate Next Generation Chip Technology: Arrival of Second Cutting Edge EUV Lithography Tool Launches New Patterning Center That Will Generate Over 100 New High Tech Jobs at SUNY Poly February 9th, 2016

COD Grad Begins Postdoctoral Fellow at Harvard University: Marsela Jorgolli's Passion for Physics Has Led to a Decade of Academic Research That Continues at Harvard University as a Postdoctoral Fellow February 2nd, 2016

Heriot-Watt's Institute of Photonics & Quantum Sciences uses the Deben Microtest 2 kN tensile stage to characterise ceramics and engineering plastics January 21st, 2016

Multiple uses for the JPK NanoWizard AFM system in the Smart Interfaces in Environmental Nanotechnology Group at the University of Illinois at Urbana-Champaign January 20th, 2016

Nanomedicine

Nanoparticle reduces targeted cancer drug's toxicity February 11th, 2016

Nanoparticle therapy that uses LDL and fish oil kills liver cancer cells February 9th, 2016

Leading bugs to the death chamber: A kinder face of cholesterol February 8th, 2016

UTHealth research looks at nanotechnology to help prevent preterm birth February 7th, 2016

Announcements

Nanoparticle reduces targeted cancer drug's toxicity February 11th, 2016

Cima NanoTech Debuts Large Interactive Touch Screens with European Customers at ISE 2016: For the first time in Europe, Cima NanoTech’s wide range of high performance, projected capacitive touch modules are showcased February 11th, 2016

Composite Pipe Long Term Testing Facility February 10th, 2016

Scientists take nanoparticle snapshots February 10th, 2016

Nanobiotechnology

Nanoparticle reduces targeted cancer drug's toxicity February 11th, 2016

Chemical cages: New technique advances synthetic biology February 10th, 2016

Nanoparticle therapy that uses LDL and fish oil kills liver cancer cells February 9th, 2016

Leading bugs to the death chamber: A kinder face of cholesterol February 8th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic