Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Mimicking the body's natural processes

Abstract:
An EU-funded research team at Norway's University of Bergen is using nanotechnology to find a way of mimicking the body's natural processes, including inducing cells to create new blood vessels for biomedically engineered tissues. The University of Bergen is involved in several major EU-funded projects, such as VascuBone ('Construction kit for tailor-made vascularized bone implants'), which has 15 partners and EUR 12 million of research funding under the Cooperation Programme of the Seventh Framework Programme (FP7). The project's remit is to improve the formation of blood vessels during the regeneration of new bone tissue.

Mimicking the body's natural processes

EU | Posted on April 14th, 2010

Biomedical and nanotechnology researchers around the world are working hard to induce cells to create new tissues. But all tissues need a blood supply and that is what the University of Bergen research team is focusing on.

The team is looking at how nanotechnology can mimic the natural processes of the body. To do so, they are investigating how cells interact with each other and with synthetic biomaterials, and what the process of regeneration involves. The aim is to understand and then copy the cells' natural mechanisms for the regeneration and engineering of new tissues.

'An ideal implant,' explained research team head Professor James Lorens from the University of Bergen, 'should mimic the body's natural tissues and send proliferation and differentiation signals to the cells. The nanoscale topology is vital for controlling how this occurs.

'A primary challenge with any tissue formation, however, is securing the blood supply to the new tissue. In other words, making sure that blood vessels are formed within the tissue.'

Professor Lorens' team is working on the blood supply aspect of tissue engineering and has already succeeded in placing three blood vessel components (epithelial and smooth muscle cells as well as matrix proteins) into an implant where cells are connected to new tissue. The experiment was successful in both Petri dishes and small implants in animals.

'We have demonstrated vessel formation in synthetic implants in our lab animals,' said Professor Lorens. 'In the next phase, we'll examine more specific tissue types such as bone tissue, for example.'

The team is also looking at ways of using nanotechnology for direct cell communication. To determine how nanostructured surfaces affect blood vessel formation, the researchers placed cells on a nanostructured biomaterial, the surface of which had been treated with certain molecules that send specific signals to cells.

'We need a better understanding of how cells perceive nanofabricated surfaces and how this affects communication between cells,' said Professor Lorens. 'By reproducing the signals that cells encounter from their immediate surroundings inside the body's various tissues, we can control how the cells proliferate and differentiate.'

Part of the research group's work is to establish how these processes work in cancerous tissues. Professor Lorens commented, 'With tissue engineering we can reproduce a tumour in order to study how it interacts with blood vessels. If we succeed in cutting the blood supply to the tumour, it will starve and die. Tumour tissue engineering can also help us to understand how cancer cells spread via blood circulation.'

The University of Bergen team is also involved in an EU collaboration to find new medications that can block the blood supply to cancerous tissues, in effect starving the cancer by depriving it of blood.

For more information, please visit:

VascuBone project: www.vascubone.fraunhofer.eu/index.html

University of Bergen: www.uib.no/en/

Research Council of Norway: www.forskningsradet.no/

####

For more information, please click here

Copyright © CORDIS

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Govt.-Legislation/Regulation/Funding/Policy

'Exotic' material is like a switch when super thin April 18th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds April 17th, 2014

INSCX™ exchange to present Exchange trade reporting mechanism for engineered nanomaterials (NMs) to UK regulation agencies, insurers and upstream/downstream users April 17th, 2014

Possible Futures

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Surface Characteristics Influence Cellular Growth on Semiconductor Material March 12th, 2014

The "Tipping Point" February 12th, 2014

Academic/Education

Director Wally Pfister joins UC Berkeley neuroengineers to discuss the science behind ‘Transcendence’ April 7th, 2014

First annual science week highlights STEM pipeline and partnerships: UB, SUNY Buffalo State and ECC team up with the City of Buffalo and its schools for April 7-11 events April 3rd, 2014

Global 450 consortium announces new general manager of internal operations: TSMC’s Cheng-Chung Chien Receives Unanimous Support, Brings History of Innovation and Efficiency to Global Consortium of Companies Driving Industry Transition to 450mm Wafer Technology March 26th, 2014

NanoTecNexus to Host "Chemistry of Wine" Fundraiser in Support of STEM Education - Collaborations Key to Success - March 20th, 2014

Nanomedicine

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

High-temperature plasmonics eyed for solar, computer innovation April 17th, 2014

Announcements

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Nanobiotechnology

Targeting cancer with a triple threat: MIT chemists design nanoparticles that can deliver three cancer drugs at a time April 15th, 2014

Biologists Develop Nanosensors to Visualize Movements and Distribution of Plant Stress Hormone April 15th, 2014

In latest generation of tiny biosensors, size isn't everything: UCLA researchers overturn conventional wisdom on nanowire-based diagnostic devices April 11th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE