Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Mimicking the body's natural processes

Abstract:
An EU-funded research team at Norway's University of Bergen is using nanotechnology to find a way of mimicking the body's natural processes, including inducing cells to create new blood vessels for biomedically engineered tissues. The University of Bergen is involved in several major EU-funded projects, such as VascuBone ('Construction kit for tailor-made vascularized bone implants'), which has 15 partners and EUR 12 million of research funding under the Cooperation Programme of the Seventh Framework Programme (FP7). The project's remit is to improve the formation of blood vessels during the regeneration of new bone tissue.

Mimicking the body's natural processes

EU | Posted on April 14th, 2010

Biomedical and nanotechnology researchers around the world are working hard to induce cells to create new tissues. But all tissues need a blood supply and that is what the University of Bergen research team is focusing on.

The team is looking at how nanotechnology can mimic the natural processes of the body. To do so, they are investigating how cells interact with each other and with synthetic biomaterials, and what the process of regeneration involves. The aim is to understand and then copy the cells' natural mechanisms for the regeneration and engineering of new tissues.

'An ideal implant,' explained research team head Professor James Lorens from the University of Bergen, 'should mimic the body's natural tissues and send proliferation and differentiation signals to the cells. The nanoscale topology is vital for controlling how this occurs.

'A primary challenge with any tissue formation, however, is securing the blood supply to the new tissue. In other words, making sure that blood vessels are formed within the tissue.'

Professor Lorens' team is working on the blood supply aspect of tissue engineering and has already succeeded in placing three blood vessel components (epithelial and smooth muscle cells as well as matrix proteins) into an implant where cells are connected to new tissue. The experiment was successful in both Petri dishes and small implants in animals.

'We have demonstrated vessel formation in synthetic implants in our lab animals,' said Professor Lorens. 'In the next phase, we'll examine more specific tissue types such as bone tissue, for example.'

The team is also looking at ways of using nanotechnology for direct cell communication. To determine how nanostructured surfaces affect blood vessel formation, the researchers placed cells on a nanostructured biomaterial, the surface of which had been treated with certain molecules that send specific signals to cells.

'We need a better understanding of how cells perceive nanofabricated surfaces and how this affects communication between cells,' said Professor Lorens. 'By reproducing the signals that cells encounter from their immediate surroundings inside the body's various tissues, we can control how the cells proliferate and differentiate.'

Part of the research group's work is to establish how these processes work in cancerous tissues. Professor Lorens commented, 'With tissue engineering we can reproduce a tumour in order to study how it interacts with blood vessels. If we succeed in cutting the blood supply to the tumour, it will starve and die. Tumour tissue engineering can also help us to understand how cancer cells spread via blood circulation.'

The University of Bergen team is also involved in an EU collaboration to find new medications that can block the blood supply to cancerous tissues, in effect starving the cancer by depriving it of blood.

For more information, please visit:

VascuBone project: www.vascubone.fraunhofer.eu/index.html

University of Bergen: www.uib.no/en/

Research Council of Norway: www.forskningsradet.no/

####

For more information, please click here

Copyright © CORDIS

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Particle Works creates range of high performance quantum dots February 23rd, 2017

GLOBALFOUNDRIES Announces Availability of 45nm RF SOI to Advance 5G Mobile Communications: Optimized RF features deliver high-performance solutions for mmWave beam forming applications in 5G smartphones and base stations February 22nd, 2017

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

JPK selects compact tensile stage from Deben for their NanoWizard® AFM platform to broaden capabilities for materials characterisation February 22nd, 2017

Govt.-Legislation/Regulation/Funding/Policy

Molecular phenomenon discovered by advanced NMR facility: Cutting edge technology has shown a molecule self-assembling into different forms when passing between solution state to solid state, and back again - a curious phenomenon in science - says research by the University of Wa February 22nd, 2017

'Lossless' metamaterial could boost efficiency of lasers and other light-based devices February 20th, 2017

Engineers shrink microscope to dime-sized device February 17th, 2017

Francis Alexander Named Deputy Director of Brookhaven Lab's Computational Science Initiative February 16th, 2017

Possible Futures

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

Tiny nanoclusters could solve big problems for lithium-ion batteries February 21st, 2017

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Breakthrough with a chain of gold atoms: In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport February 20th, 2017

Academic/Education

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Oxford Nanoimaging report on how the Nanoimager, a desktop microscope delivering single molecule, super-resolution performance, is being applied at the MRC Centre for Molecular Bacteriology & Infection November 22nd, 2016

The University of Applied Sciences in Upper Austria uses Deben tensile stages as an integral part of their computed tomography research and testing facility October 18th, 2016

Enterprise In Space Partners with Sketchfab and 3D Hubs for NewSpace Education October 13th, 2016

Nanomedicine

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Announcements

Particle Works creates range of high performance quantum dots February 23rd, 2017

GLOBALFOUNDRIES Announces Availability of 45nm RF SOI to Advance 5G Mobile Communications: Optimized RF features deliver high-performance solutions for mmWave beam forming applications in 5G smartphones and base stations February 22nd, 2017

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

JPK selects compact tensile stage from Deben for their NanoWizard® AFM platform to broaden capabilities for materials characterisation February 22nd, 2017

Nanobiotechnology

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread: Leading-Edge Research Is Part of National Cancer Moonshot Initiative February 13th, 2017

Nanobiotix appoints senior executive from pharmaceutical industry, as Chief Operating Officer: Oncology industry veteran to oversee operations and product commercialization February 8th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project