Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Mimicking the body's natural processes

Abstract:
An EU-funded research team at Norway's University of Bergen is using nanotechnology to find a way of mimicking the body's natural processes, including inducing cells to create new blood vessels for biomedically engineered tissues. The University of Bergen is involved in several major EU-funded projects, such as VascuBone ('Construction kit for tailor-made vascularized bone implants'), which has 15 partners and EUR 12 million of research funding under the Cooperation Programme of the Seventh Framework Programme (FP7). The project's remit is to improve the formation of blood vessels during the regeneration of new bone tissue.

Mimicking the body's natural processes

EU | Posted on April 14th, 2010

Biomedical and nanotechnology researchers around the world are working hard to induce cells to create new tissues. But all tissues need a blood supply and that is what the University of Bergen research team is focusing on.

The team is looking at how nanotechnology can mimic the natural processes of the body. To do so, they are investigating how cells interact with each other and with synthetic biomaterials, and what the process of regeneration involves. The aim is to understand and then copy the cells' natural mechanisms for the regeneration and engineering of new tissues.

'An ideal implant,' explained research team head Professor James Lorens from the University of Bergen, 'should mimic the body's natural tissues and send proliferation and differentiation signals to the cells. The nanoscale topology is vital for controlling how this occurs.

'A primary challenge with any tissue formation, however, is securing the blood supply to the new tissue. In other words, making sure that blood vessels are formed within the tissue.'

Professor Lorens' team is working on the blood supply aspect of tissue engineering and has already succeeded in placing three blood vessel components (epithelial and smooth muscle cells as well as matrix proteins) into an implant where cells are connected to new tissue. The experiment was successful in both Petri dishes and small implants in animals.

'We have demonstrated vessel formation in synthetic implants in our lab animals,' said Professor Lorens. 'In the next phase, we'll examine more specific tissue types such as bone tissue, for example.'

The team is also looking at ways of using nanotechnology for direct cell communication. To determine how nanostructured surfaces affect blood vessel formation, the researchers placed cells on a nanostructured biomaterial, the surface of which had been treated with certain molecules that send specific signals to cells.

'We need a better understanding of how cells perceive nanofabricated surfaces and how this affects communication between cells,' said Professor Lorens. 'By reproducing the signals that cells encounter from their immediate surroundings inside the body's various tissues, we can control how the cells proliferate and differentiate.'

Part of the research group's work is to establish how these processes work in cancerous tissues. Professor Lorens commented, 'With tissue engineering we can reproduce a tumour in order to study how it interacts with blood vessels. If we succeed in cutting the blood supply to the tumour, it will starve and die. Tumour tissue engineering can also help us to understand how cancer cells spread via blood circulation.'

The University of Bergen team is also involved in an EU collaboration to find new medications that can block the blood supply to cancerous tissues, in effect starving the cancer by depriving it of blood.

For more information, please visit:

VascuBone project: www.vascubone.fraunhofer.eu/index.html

University of Bergen: www.uib.no/en/

Research Council of Norway: www.forskningsradet.no/

####

For more information, please click here

Copyright © CORDIS

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Cool Calculations for Cold Atoms: New theory of universal three-body encounters September 2nd, 2014

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Engineers develop new sensor to detect tiny individual nanoparticles September 2nd, 2014

Future solar panels September 2nd, 2014

Govt.-Legislation/Regulation/Funding/Policy

Cool Calculations for Cold Atoms: New theory of universal three-body encounters September 2nd, 2014

UO-Berkeley Lab unveil new nano-sized synthetic scaffolding technique: Oil-and-water approach from Richmond's UO lab to spark new line of versatile peptoid nanosheets September 2nd, 2014

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Engineers develop new sensor to detect tiny individual nanoparticles September 2nd, 2014

Possible Futures

Air Force’s 30-year plan seeks 'strategic agility' August 1st, 2014

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Academic/Education

New Vice President Takes Helm at CNSE CMOST: Catherine Gilbert To Lead CNSE Children’s Museum of Science and Technology Through Expansion And Relocation August 29th, 2014

RMIT delivers $30m boost to micro and nano-tech August 26th, 2014

SEMATECH and Newly Merged SUNY CNSE/SUNYIT Launch New Patterning Center to Further Advance Materials Development: Center to Provide Access to Critical Tools that Support Semiconductor Technology Node Development August 7th, 2014

Oxford Instruments Asylum Research and the Center for Nanoscale Systems at Harvard University Present a Workshop on AFM Nanomechanical and Nanoelectrical Characterization, Aug. 21-22 August 6th, 2014

Nanomedicine

UO-Berkeley Lab unveil new nano-sized synthetic scaffolding technique: Oil-and-water approach from Richmond's UO lab to spark new line of versatile peptoid nanosheets September 2nd, 2014

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Nano-forests to reveal secrets of cells September 2nd, 2014

Nanoscale assembly line August 29th, 2014

Announcements

New synthesis method may shape future of nanostructures, clean energy: Findings advance efficient solar spliting of water into hydrogen fuel September 2nd, 2014

Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles September 2nd, 2014

Engineers develop new sensor to detect tiny individual nanoparticles September 2nd, 2014

Future solar panels September 2nd, 2014

Nanobiotechnology

UO-Berkeley Lab unveil new nano-sized synthetic scaffolding technique: Oil-and-water approach from Richmond's UO lab to spark new line of versatile peptoid nanosheets September 2nd, 2014

Nano-forests to reveal secrets of cells September 2nd, 2014

Nanoscale assembly line August 29th, 2014

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE