Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nanomaterials get to the heart of the matter

From left, Sarah Baxter, Cathy Murphy, and Edie Goldsmith
From left, Sarah Baxter, Cathy Murphy, and Edie Goldsmith

Abstract:
Having a heart of gold could have new meaning if research led by a team of USC scientists hits paydirt.

Nanomaterials get to the heart of the matter

Columbia, SC | Posted on January 23rd, 2010

The scientists are investigating how injections of nano-sized rods of gold might improve the function of faulty heart valves while eliminating the need for corrective surgery.

"Cardiac valves can become too stiff or too floppy and the heart has to work harder," said Edie Goldsmith, an associate professor in the School of Medicine's Department of Cell Biology and Anatomy. "Valve replacement surgery is an option, but we want to see if we can alter the physical structure and behavior of faulty valves with nanomaterials only."

Goldsmith and mechanical engineering associate professor Sarah Baxter are collaborating with former University chemistry professor Cathy Murphy and Clemson University bioengineering professor Delphine Dean, supported by a two-year exploratory grant from the National Institutes of Health's Heart, Lung and BloodInstitute.

"We've learned that gold nanomaterials like to associate with collagen, a structural protein," Goldsmith said. "There is too much collagen in stiff valves and not enough in floppy valves. We think that the nanomaterials can alter the mechanical properties of the collagen in beneficial ways."

The scientists have found they can modify the nano-sized gold particles with polymers creating a positive or negative surface charge that affect collagen assembly. When exposed to the nanomaterials, collagen production by fibroblasts is altered as is the phenotype of the cells.

"We want to measure the mechanical properties of collagen-fibroblast-nanoparticle constructs to see how the nanomaterials might create positive changes in the cardiac valves," Goldsmith said.

The implications of their research go beyond cardiac valve repair: the researchers plan to test the use of nanomaterials in wound healing and cancer.

"We also want to see if the nanomaterials could be used to manipulate the matrix around a tumor," she said. "You could then isolate the tumor and keep the cancer cells from spreading."

####

For more information, please click here

Contacts:
Office of Media Relations
803-777-5400

Copyright © University of South Carolina

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Industrial Nanotech, Inc. to Publish PCAOB Audited Financials July 31st, 2014

Nanostructured metal-oxide catalyst efficiently converts CO2 to methanol: Highly reactive sites at interface of 2 nanoscale components could help overcome hurdle of using CO2 as a starting point in producing useful products July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

Possible Futures

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Surface Characteristics Influence Cellular Growth on Semiconductor Material March 12th, 2014

Nanomedicine

Arrowhead to Report Fiscal 2014 Third Quarter Financial Results- Conference Call Scheduled for Tuesday, August 12, 2014 - July 31st, 2014

New imaging agent provides better picture of the gut July 30th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

Announcements

Industrial Nanotech, Inc. to Publish PCAOB Audited Financials July 31st, 2014

Nanostructured metal-oxide catalyst efficiently converts CO2 to methanol: Highly reactive sites at interface of 2 nanoscale components could help overcome hurdle of using CO2 as a starting point in producing useful products July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

New imaging agent provides better picture of the gut July 25th, 2014

Hysitron is Awarded TWO R&D 100 Awards for Highly Innovative Technology Developments in the Areas of Extreme Environments and Biological Mechanical Property Testing July 23rd, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

EPFL Research on the use of AFM based nanoscale IR spectroscopy for the study of single amyloid molecules wins poster competition at Swiss Physics Society meeting July 22nd, 2014

Nanobiotechnology

Harris & Harris Group Invests in Unique NYC Biotech Accelerator July 29th, 2014

Seeing is bead-lieving: Rice University scientists create model 'bead-spring' chains with tunable properties July 28th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE