Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Nanomaterials get to the heart of the matter

From left, Sarah Baxter, Cathy Murphy, and Edie Goldsmith
From left, Sarah Baxter, Cathy Murphy, and Edie Goldsmith

Abstract:
Having a heart of gold could have new meaning if research led by a team of USC scientists hits paydirt.

Nanomaterials get to the heart of the matter

Columbia, SC | Posted on January 23rd, 2010

The scientists are investigating how injections of nano-sized rods of gold might improve the function of faulty heart valves while eliminating the need for corrective surgery.

"Cardiac valves can become too stiff or too floppy and the heart has to work harder," said Edie Goldsmith, an associate professor in the School of Medicine's Department of Cell Biology and Anatomy. "Valve replacement surgery is an option, but we want to see if we can alter the physical structure and behavior of faulty valves with nanomaterials only."

Goldsmith and mechanical engineering associate professor Sarah Baxter are collaborating with former University chemistry professor Cathy Murphy and Clemson University bioengineering professor Delphine Dean, supported by a two-year exploratory grant from the National Institutes of Health's Heart, Lung and BloodInstitute.

"We've learned that gold nanomaterials like to associate with collagen, a structural protein," Goldsmith said. "There is too much collagen in stiff valves and not enough in floppy valves. We think that the nanomaterials can alter the mechanical properties of the collagen in beneficial ways."

The scientists have found they can modify the nano-sized gold particles with polymers creating a positive or negative surface charge that affect collagen assembly. When exposed to the nanomaterials, collagen production by fibroblasts is altered as is the phenotype of the cells.

"We want to measure the mechanical properties of collagen-fibroblast-nanoparticle constructs to see how the nanomaterials might create positive changes in the cardiac valves," Goldsmith said.

The implications of their research go beyond cardiac valve repair: the researchers plan to test the use of nanomaterials in wound healing and cancer.

"We also want to see if the nanomaterials could be used to manipulate the matrix around a tumor," she said. "You could then isolate the tumor and keep the cancer cells from spreading."

####

For more information, please click here

Contacts:
Office of Media Relations
803-777-5400

Copyright © University of South Carolina

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Doubling down on Schrödinger's cat May 27th, 2016

Finding a new formula for concrete: Researchers look to bones and shells as blueprints for stronger, more durable concrete May 26th, 2016

Deep Space Industries and SFL selected to provide satellites for HawkEye 360’s Pathfinder mission: The privately-funded space-based global wireless signal monitoring system will be developed by Deep Space Industries and UTIAS Space Flight Laboratory May 26th, 2016

Possible Futures

Doubling down on Schrödinger's cat May 27th, 2016

Harnessing solar and wind energy in one device could power the 'Internet of Things' May 26th, 2016

Thermal modification of wood and a complex study of its properties by magnetic resonance May 26th, 2016

Finding a new formula for concrete: Researchers look to bones and shells as blueprints for stronger, more durable concrete May 26th, 2016

Nanomedicine

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Supercrystals with new architecture can enhance drug synthesis May 24th, 2016

Nanoscale Trojan horses treat inflammation May 24th, 2016

Tiny packages may pack powerful treatment for brain tumors: Nanocarrier provides efficient delivery of chemotherapeutic drug May 23rd, 2016

Announcements

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Doubling down on Schrödinger's cat May 27th, 2016

Finding a new formula for concrete: Researchers look to bones and shells as blueprints for stronger, more durable concrete May 26th, 2016

Deep Space Industries and SFL selected to provide satellites for HawkEye 360’s Pathfinder mission: The privately-funded space-based global wireless signal monitoring system will be developed by Deep Space Industries and UTIAS Space Flight Laboratory May 26th, 2016

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Finding a new formula for concrete: Researchers look to bones and shells as blueprints for stronger, more durable concrete May 26th, 2016

Light can 'heal' defects in new solar cell materials: Defects in some new electronic materials can be removed by making ions move under illumination May 24th, 2016

Supercrystals with new architecture can enhance drug synthesis May 24th, 2016

Nanobiotechnology

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Supercrystals with new architecture can enhance drug synthesis May 24th, 2016

Nanoscale Trojan horses treat inflammation May 24th, 2016

Tiny packages may pack powerful treatment for brain tumors: Nanocarrier provides efficient delivery of chemotherapeutic drug May 23rd, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic