Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Nanomaterials get to the heart of the matter

From left, Sarah Baxter, Cathy Murphy, and Edie Goldsmith
From left, Sarah Baxter, Cathy Murphy, and Edie Goldsmith

Abstract:
Having a heart of gold could have new meaning if research led by a team of USC scientists hits paydirt.

Nanomaterials get to the heart of the matter

Columbia, SC | Posted on January 23rd, 2010

The scientists are investigating how injections of nano-sized rods of gold might improve the function of faulty heart valves while eliminating the need for corrective surgery.

"Cardiac valves can become too stiff or too floppy and the heart has to work harder," said Edie Goldsmith, an associate professor in the School of Medicine's Department of Cell Biology and Anatomy. "Valve replacement surgery is an option, but we want to see if we can alter the physical structure and behavior of faulty valves with nanomaterials only."

Goldsmith and mechanical engineering associate professor Sarah Baxter are collaborating with former University chemistry professor Cathy Murphy and Clemson University bioengineering professor Delphine Dean, supported by a two-year exploratory grant from the National Institutes of Health's Heart, Lung and BloodInstitute.

"We've learned that gold nanomaterials like to associate with collagen, a structural protein," Goldsmith said. "There is too much collagen in stiff valves and not enough in floppy valves. We think that the nanomaterials can alter the mechanical properties of the collagen in beneficial ways."

The scientists have found they can modify the nano-sized gold particles with polymers creating a positive or negative surface charge that affect collagen assembly. When exposed to the nanomaterials, collagen production by fibroblasts is altered as is the phenotype of the cells.

"We want to measure the mechanical properties of collagen-fibroblast-nanoparticle constructs to see how the nanomaterials might create positive changes in the cardiac valves," Goldsmith said.

The implications of their research go beyond cardiac valve repair: the researchers plan to test the use of nanomaterials in wound healing and cancer.

"We also want to see if the nanomaterials could be used to manipulate the matrix around a tumor," she said. "You could then isolate the tumor and keep the cancer cells from spreading."

####

For more information, please click here

Contacts:
Office of Media Relations
803-777-5400

Copyright © University of South Carolina

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

Possible Futures

Global Carbon Nanotubes (CNT) Market Expected To Reach USD 3.42 Billion By 2022 May 29th, 2015

Global Nano-Enabled Packaging Market For Food and Beverages Will Reach $15.0 billion in 2020 May 26th, 2015

Simulations predict flat liquid May 21st, 2015

Nature inspires first artificial molecular pump: Simple design mimics pumping mechanism of life-sustaining proteins found in living cells May 19th, 2015

Nanomedicine

New chip makes testing for antibiotic-resistant bacteria faster, easier: Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time May 28th, 2015

Arrowhead to Present at Jefferies 2015 Healthcare Conference May 27th, 2015

Seeing the action: UCSB researchers develop a novel device to image the minute forces and actions involved in cell membrane hemifusion May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Announcements

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

One step closer to a single-molecule device: Columbia Engineering researchers first to create a single-molecule diode -- the ultimate in miniaturization for electronic devices -- with potential for real-world applications May 25th, 2015

What makes cancer cells spread? New device offers clues May 19th, 2015

Researchers build new fermion microscope: Instrument freezes and images 1,000 individual fermionic atoms at once May 13th, 2015

Nanobiotechnology

New technique speeds nanoMRI imaging: Multiplexing technique for nanoscale magnetic resonance imaging developed by researchers in Switzerland cuts normal scan time from two weeks to two days May 28th, 2015

Seeing the action: UCSB researchers develop a novel device to image the minute forces and actions involved in cell membrane hemifusion May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Who needs water to assemble DNA? Non-aqueous solvent supports DNA nanotechnology May 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project