Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Breakthrough Breast Cancer Therapy Reduces Mastectomies; Saves Breast

Abstract:
Heat treatment with chemotherapy kills large tumors; Approved by FDA; Next stage clinical trials start this year at OUHSC

Breakthrough Breast Cancer Therapy Reduces Mastectomies; Saves Breast

Oklahoma City, OK | Posted on January 19th, 2010

A new treatment developed and tested by University of Oklahoma researchers not only killed large cancer tumors, but reduced the need for mastectomies by almost 90 percent. The latest results appear in an upcoming issue of the Annals of Surgical Oncology.

Building on this success, researchers at the OU Health Sciences Center, plan to start the next phase of clinical trials this year to test the therapy on even larger tumors.

"This therapy is a major advancement for women with later stage breast cancer. Right now, most patients with large tumors lose their breast. With this treatment along with chemotherapy, we were able to kill the cancer and save the breast tissue," said William Dooley, M.D., a researcher at the OU Cancer Institute and the director of surgical oncology at OU Medicine.

Dr. Dooley is leading a group of researchers from OU, the Massachusetts Institute of Technology, the Los Angeles Biomedical Research Institute, the Comprehensive Breast Center in Florida and St. Joseph's Hospital in California.

They are working on a treatment called Focused Microwave Thermotherapy. The technique, which was approved by the U.S. Food and Drug Administration, uses a modified version of the microwave technology behind the "Star Wars" defense system.

In the most recent study, researchers tested the therapy on tumors that were an inch to an inch and a half in size. These large tumors usually require mastectomies. When researchers used the heating therapy within two hours of patients receiving chemotherapy, the tumor was more susceptible to the chemotherapy and shrunk rapidly. The percentage of patients needing mastectomies was reduced from 75 percent to 7 percent.

"The trial was very successful. We were able to completely reverse those odds," Dooley said. "We redesigned the machine and will begin clinical trials this year to determine whether the therapy works on tumors that are larger than one and a half inches and smaller than 5 inches in size."

In theory, Dooley said the technique could be used on any organ that could be "held relatively still." Scientists are now working to integrate heat-sensitive nanotechnology that would more precisely target cancer cells. They also plan to study a byproduct of the rapid disintegration of the tumor - a boosted immune system. Dooley said it looks like the rapid release of cancer proteins into the blood stream is causing an immune response that could reduce the chance of cancer recurrence.

Find the latest research results online at springerlink.com/content/g105331202416323/.

####

About University of Oklahoma Health Sciences Center
As Oklahoma’s only comprehensive academic cancer center, the OU Cancer Institute is raising the standard of cancer treatment in the state through research and education. The center is working toward an application to the National Cancer Institute to be designated as a “Comprehensive Cancer Center,” the gold standard of cancer research and care. Later this year, the OU Cancer Institute will move into a new 210,000-square-foot building. The facility will bring all outpatient cancer programs under one roof at the University of Oklahoma Health Sciences Center.

For more information, please click here

Copyright © University of Oklahoma Health Sciences Center

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Artificial blood vessels become resistant to thrombosis August 4th, 2015

Engineering a better 'Do: Purdue researchers are learning how August 4th, 2015

Proving nanoparticles in sunscreen products August 4th, 2015

Global Carbon Nanotubes Industry 2015: Acute Market Reports August 4th, 2015

Possible Futures

Global Carbon Nanotubes Industry 2015: Acute Market Reports August 4th, 2015

Nanozirconia Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Self-Healing Nano Anti-rust Coatings Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Nano Spray Instrument Market 2015 - Global Industry Survey, Analysis, Size, Share, Outlook and Forecast to 2020 July 31st, 2015

Nanomedicine

Artificial blood vessels become resistant to thrombosis August 4th, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Announcements

Artificial blood vessels become resistant to thrombosis August 4th, 2015

Engineering a better 'Do: Purdue researchers are learning how August 4th, 2015

Proving nanoparticles in sunscreen products August 4th, 2015

Global Carbon Nanotubes Industry 2015: Acute Market Reports August 4th, 2015

Nanobiotechnology

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

European Technology Platform for Nanomedicine and ENATRANS European Consortium Launch the 2nd edition of the Nanomedicine Award: The Award to be presented at BIO-Europe conference in Munich, November 2015 July 30th, 2015

New computer model could explain how simple molecules took first step toward life: Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules July 28th, 2015

Spintronics: Molecules stabilizing magnetism: Organic molecules fixing the magnetic orientation of a cobalt surface/ building block for a compact and low-cost storage technology/ publication in Nature Materials July 25th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project