Home > News > Beyond the Abstract - Biological in situ dose painting for image-guided radiation therapy using drug-loaded implantable devices
January 18th, 2010
Beyond the Abstract - Biological in situ dose painting for image-guided radiation therapy using drug-loaded implantable devices
Abstract:
Methods to augment the biological action of radiation therapy in prostate and other tumors without additional toxicity to surrounding normal tissues would be useful for improving the therapeutic ratio.
In order to achieve high spatial accuracy, modern radiation therapy practice routinely utilizes implantation of fiducials (external beam therapy) or radioactive source spacers (brachytherapy) into the tumor. These implantable devices are an essential technical component of radiation delivery during Image Guided Radiation Therapy (IGRT), but are inert and provide no direct therapeutic function.
The next step will be to test the method (termed BIS-IGRT, Biological In-Situ enhanced IGRT) in animal models. A series of drug-loaded devices is under development for this purpose, in collaboration with nanotechnology and nanomedicine experts at Northeastern University, in order to look at the tumor-sensitizing properties of the implants.
Source:
urotoday.com
Bookmark:
News and information
Whirlpools on the Nanoscale Could Multiply Magnetic Memory: At the Advanced Light Source, Berkeley Lab scientists join an international team to control spin orientation in magnetic nanodisks May 22nd, 2013
Bacterial spare parts filter antibiotic residue from groundwater May 22nd, 2013
UofL scientists uncover how grapefruits provide a secret weapon in medical drug delivery May 22nd, 2013
Atomic-Scale Investigations Solve Key Puzzle of LED Efficiency: MIT and Brookhaven Lab scientists use electron microscopy imaging techniques to settle a solid-state controversy and raise new experimental possibilities May 22nd, 2013
Nanomedicine
UofL scientists uncover how grapefruits provide a secret weapon in medical drug delivery May 22nd, 2013
Single-Cell Transfection Tool Enables Added Control for Biological Studies: McCormick researchers develop method of delivering molecules into targeted cells May 22nd, 2013
How Gold Nanoparticles Can Help Fight Ovarian Cancer May 21st, 2013
MU Researchers Develop Radioactive Nanoparticles that Target Cancer Cells: This is an early step toward developing therapies for metastasized cancers, MU scientist says May 21st, 2013
Announcements
Whirlpools on the Nanoscale Could Multiply Magnetic Memory: At the Advanced Light Source, Berkeley Lab scientists join an international team to control spin orientation in magnetic nanodisks May 22nd, 2013
Bacterial spare parts filter antibiotic residue from groundwater May 22nd, 2013
UofL scientists uncover how grapefruits provide a secret weapon in medical drug delivery May 22nd, 2013
Atomic-Scale Investigations Solve Key Puzzle of LED Efficiency: MIT and Brookhaven Lab scientists use electron microscopy imaging techniques to settle a solid-state controversy and raise new experimental possibilities May 22nd, 2013
Nanobiotechnology
Bacterial spare parts filter antibiotic residue from groundwater May 22nd, 2013
Single-Cell Transfection Tool Enables Added Control for Biological Studies: McCormick researchers develop method of delivering molecules into targeted cells May 22nd, 2013
Researchers Perform Fastest Measurements Ever Made of Ion Channel Proteins May 20th, 2013
Artificial Forest for Solar Water-Splitting: Berkeley Lab Researchers Report First Fully Integrated Artificial Photosynthesis Nanosystem May 17th, 2013