Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Using Nanotechnology to Boost the Lifespan of Medical Implants

Professor Leon Shaw with a graduate student in his lab at the Institute of Materials Science. Photo by Peter Morenus
Professor Leon Shaw with a graduate student in his lab at the Institute of Materials Science. Photo by Peter Morenus

Abstract:
His work in the red-hot area of nanotechnology has sparked three NSF-funded research awards for Leon Shaw, a professor in the Department of Chemical, Materials, & Biomolecular Engineering.

Using Nanotechnology to Boost the Lifespan of Medical Implants

Storrs, CT | Posted on January 9th, 2010

Of the three, one marries nano-materials with biomedical engineering. Together with Yong Wang, an assistant professor of chemical, materials, and biomolecular engineering, Shaw will work on developing a titanium/hydroxyapatite orthopedic implant designed to improve implant longevity and reduce the need for revision surgery, thus reducing long-term health care costs and patient stress.

Over 10 million Americans currently carry at least one major implanted medical device in their bodies. Due to their excellent corrosion resistance, superior strength, and biocompatibility, titanium and stainless steel alloys are the principal materials used in most medical implants. Despite their advantages, these alloys also carry major disadvantages: in many cases, their life expectancy is shorter than those of their wearers, prompting additional replacement implant surgeries.

In addition, titanium and steel alloys are unlikely to have the stability or fit of the original tissue, leading to rejection of the implant. While currently available implants may alleviate pain and allow patients to live active lives, there are often complications getting bone to attach to the metal devices. Small gaps between natural bone and the implant can expand over time, requiring additional surgery to replace the implant. Researchers are increasingly turning to nanotechnology for solutions.

To overcome the problems associated with metallic implants, many research organizations and commercial companies have tried to develop orthopedic implants that have a bioactive surface to promote cellular adhesion and bony in-growth. Efforts have been made to create a stable fit that more closely resembles the original tissue, thus eliminating the need for additional surgery to repair the damage or gaps.

The two most widely used methods involve the application of either hydroxyapatite or porous titanium coatings to implant surfaces. The problem is that titanium is not bioactive, whereas hydroxyapatite coatings could delaminate during use. With this in mind, Shaw and Wang have geared their project toward the development of a new family of functionally graded, porous implant materials with a hierarchy of engineered microstructures. This new family of orthopedic implants will address the issues by applying either hydroxyapatite or porous titanium coatings and will be fabricated through a novel solid freeform fabrication method developed in Shaw's laboratory. This type of orthopedic implants is the first of its kind to pair a titanium-rich core and a hydroxyapatite-rich surface with a controlled level of micro- and macro-porosity never produced previously.

Shaw's other NSF grants are also collaborative efforts. Shaw will be teaming with Kennametal Inc., a global leader in hard metal technology. This project is aimed at the development of innovative manufacturing methods that can produce novel materials with superior mechanical properties derived from nanocrystalline powder. The collaboration will ensure that the research is relevant to the hard metal industry and that the results will be disseminated to end users.

The third research project is in collaboration with Mahmoud Zawrah, a researcher from the National Research Center in Cairo, Egypt. Together, they are looking at the processing and fabrication of nano-Si3N4 and SiC composites using the waste material silica fume as the starting material. If successful, this project will lead to advancements in the production of large quantities of high purity nano-composite powders and sintered (or densified) Si3N4/SiC components from silica fume in a reproducible, precise, and economical fashion.

####

About University of Connecticut
Perennially ranked the top public university in New England, the University of Connecticut now stands among the best public institutions in the nation. UConns main campus in Storrs is admitting the highest-achieving freshmen in University history. Student diversity continues to increase, as does the number of honors students, valedictorians and salutatorians who consistently make UConn their top choice.

For more information, please click here

Copyright © University of Connecticut

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Gold standards for nanoparticles: Understanding how small organic ions stabilize gold nanoparticles may allow for better control March 29th, 2017

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Researchers uncover secret of nanomaterial that makes harvesting sunlight easier March 29th, 2017

Information storage with a nanoscale twist: Discovery of a novel rotational force inside magnetic vortices makes it easier to design ultrahigh capacity disk drives March 28th, 2017

Govt.-Legislation/Regulation/Funding/Policy

A big leap toward tinier lines: Self-assembly technique could lead to long-awaited, simple method for making smaller microchip patterns March 27th, 2017

Laser activated gold pyramids could deliver drugs, DNA into cells without harm: Microstructures create temporary pores in cells March 27th, 2017

Cryo-electron microscopy achieves unprecedented resolution using new computational methods March 25th, 2017

Argon is not the 'dope' for metallic hydrogen March 24th, 2017

Nanomedicine

Gold standards for nanoparticles: Understanding how small organic ions stabilize gold nanoparticles may allow for better control March 29th, 2017

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Laser activated gold pyramids could deliver drugs, DNA into cells without harm: Microstructures create temporary pores in cells March 27th, 2017

Researchers make flexible glass for tiny medical devices: Glass can bend over and over again on a nanoscale March 27th, 2017

Announcements

Gold standards for nanoparticles: Understanding how small organic ions stabilize gold nanoparticles may allow for better control March 29th, 2017

Tiny sensor lays groundwork for precision X-rays detection via endoscopy:Nanoscale fiber-integrated X-ray sensor opens new doors for medical imaging and radiotherapy March 29th, 2017

Researchers uncover secret of nanomaterial that makes harvesting sunlight easier March 29th, 2017

Information storage with a nanoscale twist: Discovery of a novel rotational force inside magnetic vortices makes it easier to design ultrahigh capacity disk drives March 28th, 2017

Nanobiotechnology

Gold standards for nanoparticles: Understanding how small organic ions stabilize gold nanoparticles may allow for better control March 29th, 2017

Laser activated gold pyramids could deliver drugs, DNA into cells without harm: Microstructures create temporary pores in cells March 27th, 2017

Cryo-electron microscopy achieves unprecedented resolution using new computational methods March 25th, 2017

Nanobiotix: The Independent Data Monitoring Committee Recommends the Continuation of the Ongoing Phase II/III Trial of NBTXR3 in Soft Tissue Sarcoma March 23rd, 2017

Alliances/Trade associations/Partnerships/Distributorships

ATTOPSEMI Technology Joins FDXcelerator Program to Deliver Advanced Non-Volatile Memory IP to GLOBALFOUNDRIES 22 FDX Technology Platform: Leading-edge I-fuse brings higher reliability, smaller cell size and ease of programmability for consumer, automotive, and IoT applications March 27th, 2017

Leti and HORIBA Scientific to Host Webinar on Ultrafast Characterization Tool: Plasma Profiling Time-of-Flight Mass Spectrometer Tool Cuts Optimization Time In Layer Deposition and Fabrication of Wide Range of Applications March 27th, 2017

AIM Photonics Welcomes Coventor as Newest Member: US-Backed Initiative Taps Process Modeling Specialist to Enable Manufacturing of High-Yield, High-Performance Integrated Photonic Designs March 16th, 2017

Applied Graphene Materials plc - Significant commercial progress in AGMs three core sectors March 3rd, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project