Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Using Nanotechnology to Boost the Lifespan of Medical Implants

Professor Leon Shaw with a graduate student in his lab at the Institute of Materials Science. Photo by Peter Morenus
Professor Leon Shaw with a graduate student in his lab at the Institute of Materials Science. Photo by Peter Morenus

Abstract:
His work in the red-hot area of nanotechnology has sparked three NSF-funded research awards for Leon Shaw, a professor in the Department of Chemical, Materials, & Biomolecular Engineering.

Using Nanotechnology to Boost the Lifespan of Medical Implants

Storrs, CT | Posted on January 9th, 2010

Of the three, one marries nano-materials with biomedical engineering. Together with Yong Wang, an assistant professor of chemical, materials, and biomolecular engineering, Shaw will work on developing a titanium/hydroxyapatite orthopedic implant designed to improve implant longevity and reduce the need for revision surgery, thus reducing long-term health care costs and patient stress.

Over 10 million Americans currently carry at least one major implanted medical device in their bodies. Due to their excellent corrosion resistance, superior strength, and biocompatibility, titanium and stainless steel alloys are the principal materials used in most medical implants. Despite their advantages, these alloys also carry major disadvantages: in many cases, their life expectancy is shorter than those of their wearers, prompting additional replacement implant surgeries.

In addition, titanium and steel alloys are unlikely to have the stability or fit of the original tissue, leading to rejection of the implant. While currently available implants may alleviate pain and allow patients to live active lives, there are often complications getting bone to attach to the metal devices. Small gaps between natural bone and the implant can expand over time, requiring additional surgery to replace the implant. Researchers are increasingly turning to nanotechnology for solutions.

To overcome the problems associated with metallic implants, many research organizations and commercial companies have tried to develop orthopedic implants that have a bioactive surface to promote cellular adhesion and bony in-growth. Efforts have been made to create a stable fit that more closely resembles the original tissue, thus eliminating the need for additional surgery to repair the damage or gaps.

The two most widely used methods involve the application of either hydroxyapatite or porous titanium coatings to implant surfaces. The problem is that titanium is not bioactive, whereas hydroxyapatite coatings could delaminate during use. With this in mind, Shaw and Wang have geared their project toward the development of a new family of functionally graded, porous implant materials with a hierarchy of engineered microstructures. This new family of orthopedic implants will address the issues by applying either hydroxyapatite or porous titanium coatings and will be fabricated through a novel solid freeform fabrication method developed in Shaw's laboratory. This type of orthopedic implants is the first of its kind to pair a titanium-rich core and a hydroxyapatite-rich surface with a controlled level of micro- and macro-porosity never produced previously.

Shaw's other NSF grants are also collaborative efforts. Shaw will be teaming with Kennametal Inc., a global leader in hard metal technology. This project is aimed at the development of innovative manufacturing methods that can produce novel materials with superior mechanical properties derived from nanocrystalline powder. The collaboration will ensure that the research is relevant to the hard metal industry and that the results will be disseminated to end users.

The third research project is in collaboration with Mahmoud Zawrah, a researcher from the National Research Center in Cairo, Egypt. Together, they are looking at the processing and fabrication of nano-Si3N4 and SiC composites using the waste material silica fume as the starting material. If successful, this project will lead to advancements in the production of large quantities of high purity nano-composite powders and sintered (or densified) Si3N4/SiC components from silica fume in a reproducible, precise, and economical fashion.

####

About University of Connecticut
Perennially ranked the top public university in New England, the University of Connecticut now stands among the best public institutions in the nation. UConn’s main campus in Storrs is admitting the highest-achieving freshmen in University history. Student diversity continues to increase, as does the number of honors students, valedictorians and salutatorians who consistently make UConn their top choice.

For more information, please click here

Copyright © University of Connecticut

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

'Exotic' material is like a switch when super thin April 18th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Oxford Instruments Asylum Research Introduces the MFP-3D InfinityTM AFM Featuring Powerful New Capabilities and Stunning High Performance April 18th, 2014

Conductive Inks: booming to $2.8 billion by 2024 April 17th, 2014

Govt.-Legislation/Regulation/Funding/Policy

'Exotic' material is like a switch when super thin April 18th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds April 17th, 2014

INSCX™ exchange to present Exchange trade reporting mechanism for engineered nanomaterials (NMs) to UK regulation agencies, insurers and upstream/downstream users April 17th, 2014

Nanomedicine

Innovative strategy to facilitate organ repair April 18th, 2014

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds April 17th, 2014

More effective kidney stone treatment, from the macroscopic to the nanoscale April 17th, 2014

High-temperature plasmonics eyed for solar, computer innovation April 17th, 2014

Announcements

'Exotic' material is like a switch when super thin April 18th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Oxford Instruments Asylum Research Introduces the MFP-3D InfinityTM AFM Featuring Powerful New Capabilities and Stunning High Performance April 18th, 2014

Transparent Conductive Films and Sensors Are Hot Segments in Printed Electronics: Start-ups in these fields show above-average momentum, while companies working on emissive displays such as OLED are fading, Lux Research says April 17th, 2014

Nanobiotechnology

Targeting cancer with a triple threat: MIT chemists design nanoparticles that can deliver three cancer drugs at a time April 15th, 2014

Biologists Develop Nanosensors to Visualize Movements and Distribution of Plant Stress Hormone April 15th, 2014

In latest generation of tiny biosensors, size isn't everything: UCLA researchers overturn conventional wisdom on nanowire-based diagnostic devices April 11th, 2014

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Alliances/Partnerships/Distributorships

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Peer Reviewed and Approved for Science by the the Washington Academy of Sciences April 3rd, 2014

New JEOL-Nikon MiXcroscopy Correlative Imaging Solution March 27th, 2014

Quantum Dots Take Center Stage at Inaugural Event: QD Vision Co-Founder and CTO Dr. Seth Coe-Sullivan to Chair First Quantum Dots Forum, March 26, 2014, San Diego, CA March 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE