Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > News > Stabilization of the Nitric Oxide (NO) Prodrugs and Anticancer Leads, PABA/NO and Double JS-K, through Incorporation into PEG-Protected Nanoparticles

January 6th, 2010

Stabilization of the Nitric Oxide (NO) Prodrugs and Anticancer Leads, PABA/NO and Double JS-K, through Incorporation into PEG-Protected Nanoparticles

Abstract:
We report the stabilization of the nitric oxide (NO) prodrugs and anticancer lead compounds, PABA/NO (O2-{2,4-dinitro-5-[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2-diolate) and "Double JS-K" 1,5-bis-{1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diol-2-ato}-2,4-dinitrobenzene, through their incorporation into polymer-protected nanoparticles. The prodrugs were formulated in block copolymer-stabilized nanoparticles with sizes from 220 to 450 nm by a novel rapid precipitation process.

Source:
acs.org

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

'Gyroscope' molecules form crystal that's both solid and full of motion: New type of molecular machine designed by UCLA researchers could have wide-ranging applications in technology and science January 16th, 2018

The nanoscopic structure that locks up our genes January 16th, 2018

New exotic phenomena seen in photonic crystals: Researchers observe, for the first time, topological effects unique to an “open” system January 12th, 2018

Nanotube fibers in a jiffy: Rice University lab makes short nanotube samples by hand to dramatically cut production time January 11th, 2018

Chemistry

'Gyroscope' molecules form crystal that's both solid and full of motion: New type of molecular machine designed by UCLA researchers could have wide-ranging applications in technology and science January 16th, 2018

Nanomedicine

The nanoscopic structure that locks up our genes January 16th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Rice University lab modifies nanoscale virus to deliver peptide drugs to cells, tissues January 8th, 2018

SNUH team develops new nanomaterial for thermal cancer therapy January 5th, 2018

Announcements

'Gyroscope' molecules form crystal that's both solid and full of motion: New type of molecular machine designed by UCLA researchers could have wide-ranging applications in technology and science January 16th, 2018

The nanoscopic structure that locks up our genes January 16th, 2018

New exotic phenomena seen in photonic crystals: Researchers observe, for the first time, topological effects unique to an “open” system January 12th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Nanobiotechnology

The nanoscopic structure that locks up our genes January 16th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Rice University lab modifies nanoscale virus to deliver peptide drugs to cells, tissues January 8th, 2018

Novel nanomedicine inhibits progression of pancreatic cancer in mice: Survival rates in pancreatic cancer linked to inverse correlation between specific oncogene and tumor suppressant, Tel Aviv University researchers say January 3rd, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project