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Home > News > U-M scientists win $6.8 million in federal stimulus-fund grants for stem cell research

November 6th, 2009

U-M scientists win $6.8 million in federal stimulus-fund grants for stem cell research

Abstract:
University of Michigan researchers have been awarded 13 federal stimulus-fund grants to date, totaling $6.8 million, for research projects involving both adult and embryonic stem cells.

Liang Xu, assistant professor of radiation oncology at the Medical School, was awarded $614,396 to explore a nanoparticle-based system for targeted delivery of miRNA-based therapeutics to human pancreatic cancer stem cells. MicroRNAs, or miRNAS, are single-stranded RNA molecules that regulate gene expression in a cell. Xu's work could lead to novel, self-assembled miRNA-nanovectors that can deliver the known tumor suppressor miR-34 to pancreatic cancer stem cells, inhibiting their self-renewal and tumor initiation.

Source:
University of Michigan

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