Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > UCF developing diagnostic tool kit for dementia

Abstract:
UCF researchers are teaming up with Boston University to develop a miniature diagnostic tool kit that will detect the early onset of neurodegenerative diseases such as Alzheimer's and Parkinson's.

By Monica Agatstein

UCF developing diagnostic tool kit for dementia

Orlando, FL | Posted on October 29th, 2009

According to the World Alzheimer Report, which is published by Alzheimer's Disease International (ADI), an estimated 35.6 million people worldwide will be living with dementia in 2010. The disease is the sixth leading cause of death in the nation.

"Alzheimer's and Parkinson's disease are going to affect society in a big way because so many people are going to be affected in the next year or so," said Sudipta Seal, director of UCF's NanoScience Technology and Advanced Materials Processing and Analysis Center. "Early detection of Alzheimer's and Parkinson's is very important and that is what we're going to do."

The $346,000 collaborative research project is being funded by the National Science Foundation and will take place over the course of three years, Seal said.

Seal is also working with Hyoung-Jin Cho, an associate professor of mechanical, materials and aerospace engineering and a researcher at the NanoScience Technology Center.

"If we can understand what is causing these diseases, we can have better care in the future," Seal said.

The device is being built at UCF while research is also being conducted at Boston University with Dr. Lee Goldstein. Goldstein is an associate professor in psychiatry, neurology, ophthalmology, pathology and laboratory medicine, and biomedical engineering and photonics. He was introduced to Seal at a conference where they discussed their research. That interaction led to the collaboration on the project.

The main goal is to understand the basic biology of these diseases and this tool will also enable the development of new diagnostics and new treatments, Goldstein said.

The project will use "nanoparticles on a chip about the size of a credit card to detect damaging levels of oxygen byproducts in the central nervous system," according to a UCF News & Information article. The byproducts, known as reactive oxygen species, are a main component of serious neurodegenerative diseases, and the research conducted throughout this project will give a better understanding of these byproducts, potentially giving way to more effective treatments.

The early symptoms of dementia include memory loss, difficulty performing familiar tasks, problems with language, disorientation to time and place, poor or decreased judgment, problems with keeping track of things, changes in mood or behavior, changes in personality and loss of initiative, according to ADI.

An existing diagnosis process involves studying the history of the person's problem from a close relative or friend in addition to an examination of the person's physical and mental status. There is no simple test and dementia can only be confirmed by an examination of the brain post-mortem, according to ADI.

The new device will be more sensitive and cost effective. After three years the project is planned to move to animal trial and the device may be completed in an estimated seven to nine years, Seal said.

"I believe that the number [of people with Alzheimer's] is significantly larger than those who are diagnosed because we are unable to detect the disease early or separate it from other disorders," Goldstein said. "We're dealing with a national health care crisis and there is a tremendous urgency for this."

####

About University of Central Florida
The University of Central Florida is one of the most dynamic universities in the country. Offering 225 degree programs, it has become an academic and research leader in numerous fields, such as optics, modeling and simulation, engineering and computer science, business administration, education, science, hospitality management and digital media.

UCF’s 1,415-acre main campus provides modern facilities, most of which have wireless abilities, with 600 acres set aside for lakes, woods and an arboretum. UCF now has 12 colleges, including the newly established College of Medicine, and College of Graduate Studies. More than 53,000 students attend classes on UCF's main campus and its 11 regional campuses located throughout Central Florida. UCF has granted more than 186,000 degrees in its 40 years of offering classes.

For more information, please click here

Copyright © University of Central Florida

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

ICN2 researchers compute unprecedented values for spin lifetime anisotropy in graphene November 17th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Govt.-Legislation/Regulation/Funding/Policy

EC Project Aims at Creating and Commercializing Cyber-Physical-System Solutions November 14th, 2017

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3’s significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Leti Joins DARPA-Funded Project to Develop Implantable Device for Restoring Vision November 9th, 2017

Nanoshells could deliver more chemo with fewer side effects: In vitro study verifies method for remotely triggering release of cancer drugs November 8th, 2017

Possible Futures

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

GLOBALFOUNDRIES Demonstrates Industry-Leading 112G Technology for Next-Generation Connectivity Solutions: High bandwidth, low power SerDes IP portfolio enables ‘connected intelligence’ in data centers and networking applications November 15th, 2017

Nanomedicine

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3’s significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Arrowhead to Present at 29th Annual Piper Jaffray Healthcare Conference November 14th, 2017

A new way to mix oil and water: Condensation-based method developed at MIT could create stable nanoscale emulsions November 8th, 2017

Sensors

The stacked color sensor: True colors meet minimization November 16th, 2017

Promising sensors for submarines, mines and spacecraft: MSU scientists are developing nanostructured gas sensors that would work at room temperature November 10th, 2017

Practical superconducting nanowire single photon detector with record detection efficiency over 90 percent November 9th, 2017

Dendritic fibrous nanosilica: all-in-one nanomaterial for energy, environment and health November 4th, 2017

Announcements

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

ICN2 researchers compute unprecedented values for spin lifetime anisotropy in graphene November 17th, 2017

Math gets real in strong, lightweight structures: Rice University researchers use 3-D printers to turn century-old theory into complex schwarzites November 16th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Nanobiotechnology

Nanoparticles could allow for faster, better medicine: Exposure of nanoparticles in the body allows for more effective delivery November 20th, 2017

Nanobiotix presented new clinical and pre-clinical data confirming NBTXR3’s significant potential role in Immuno-Oncology at SITC Annual Meeting November 14th, 2017

Arrowhead to Present at 29th Annual Piper Jaffray Healthcare Conference November 14th, 2017

Nanoshells could deliver more chemo with fewer side effects: In vitro study verifies method for remotely triggering release of cancer drugs November 8th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project