Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > UCF developing diagnostic tool kit for dementia

Abstract:
UCF researchers are teaming up with Boston University to develop a miniature diagnostic tool kit that will detect the early onset of neurodegenerative diseases such as Alzheimer's and Parkinson's.

By Monica Agatstein

UCF developing diagnostic tool kit for dementia

Orlando, FL | Posted on October 29th, 2009

According to the World Alzheimer Report, which is published by Alzheimer's Disease International (ADI), an estimated 35.6 million people worldwide will be living with dementia in 2010. The disease is the sixth leading cause of death in the nation.

"Alzheimer's and Parkinson's disease are going to affect society in a big way because so many people are going to be affected in the next year or so," said Sudipta Seal, director of UCF's NanoScience Technology and Advanced Materials Processing and Analysis Center. "Early detection of Alzheimer's and Parkinson's is very important and that is what we're going to do."

The $346,000 collaborative research project is being funded by the National Science Foundation and will take place over the course of three years, Seal said.

Seal is also working with Hyoung-Jin Cho, an associate professor of mechanical, materials and aerospace engineering and a researcher at the NanoScience Technology Center.

"If we can understand what is causing these diseases, we can have better care in the future," Seal said.

The device is being built at UCF while research is also being conducted at Boston University with Dr. Lee Goldstein. Goldstein is an associate professor in psychiatry, neurology, ophthalmology, pathology and laboratory medicine, and biomedical engineering and photonics. He was introduced to Seal at a conference where they discussed their research. That interaction led to the collaboration on the project.

The main goal is to understand the basic biology of these diseases and this tool will also enable the development of new diagnostics and new treatments, Goldstein said.

The project will use "nanoparticles on a chip about the size of a credit card to detect damaging levels of oxygen byproducts in the central nervous system," according to a UCF News & Information article. The byproducts, known as reactive oxygen species, are a main component of serious neurodegenerative diseases, and the research conducted throughout this project will give a better understanding of these byproducts, potentially giving way to more effective treatments.

The early symptoms of dementia include memory loss, difficulty performing familiar tasks, problems with language, disorientation to time and place, poor or decreased judgment, problems with keeping track of things, changes in mood or behavior, changes in personality and loss of initiative, according to ADI.

An existing diagnosis process involves studying the history of the person's problem from a close relative or friend in addition to an examination of the person's physical and mental status. There is no simple test and dementia can only be confirmed by an examination of the brain post-mortem, according to ADI.

The new device will be more sensitive and cost effective. After three years the project is planned to move to animal trial and the device may be completed in an estimated seven to nine years, Seal said.

"I believe that the number [of people with Alzheimer's] is significantly larger than those who are diagnosed because we are unable to detect the disease early or separate it from other disorders," Goldstein said. "We're dealing with a national health care crisis and there is a tremendous urgency for this."

####

About University of Central Florida
The University of Central Florida is one of the most dynamic universities in the country. Offering 225 degree programs, it has become an academic and research leader in numerous fields, such as optics, modeling and simulation, engineering and computer science, business administration, education, science, hospitality management and digital media.

UCF’s 1,415-acre main campus provides modern facilities, most of which have wireless abilities, with 600 acres set aside for lakes, woods and an arboretum. UCF now has 12 colleges, including the newly established College of Medicine, and College of Graduate Studies. More than 53,000 students attend classes on UCF's main campus and its 11 regional campuses located throughout Central Florida. UCF has granted more than 186,000 degrees in its 40 years of offering classes.

For more information, please click here

Copyright © University of Central Florida

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Particle Works creates range of high performance quantum dots February 23rd, 2017

Govt.-Legislation/Regulation/Funding/Policy

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Molecular phenomenon discovered by advanced NMR facility: Cutting edge technology has shown a molecule self-assembling into different forms when passing between solution state to solid state, and back again - a curious phenomenon in science - says research by the University of Wa February 22nd, 2017

'Lossless' metamaterial could boost efficiency of lasers and other light-based devices February 20th, 2017

Possible Futures

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

EmTech Asia breaks new barriers with potential applications of space exploration with NASA and MIT February 22nd, 2017

Tiny nanoclusters could solve big problems for lithium-ion batteries February 21st, 2017

Nanomedicine

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

Sensors

Strem Chemicals and Dotz Nano Ltd. Sign Distribution Agreement for Graphene Quantum Dots Collaboration February 21st, 2017

Liquid metal nano printing set to revolutionize electronics: Creating integrated circuits just atoms thick February 18th, 2017

Research opens door to smaller, cheaper, more agile communications tech February 16th, 2017

Metamaterial: Mail armor inspires physicists: KIT researchers reverse hall coefficient -- medieval mail armor inspired development of metamaterial with novel properties February 15th, 2017

Announcements

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Particle Works creates range of high performance quantum dots February 23rd, 2017

Nanobiotechnology

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

In-cell molecular sieve from protein crystal February 14th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project