Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > JEOL Introduces a New Correlative Microscopy Tool for Observing Biological Samples and Materials in Atmosphere

New JEOL ClairScope ™ Correlative Microscope
New JEOL ClairScope ™ Correlative Microscope

Abstract:
New ClairScope tm Combines Atmospheric Scanning Electron Microscope (ASEM) with Light Microscope

JEOL Introduces a New Correlative Microscopy Tool for Observing Biological Samples and Materials in Atmosphere

Peabody, MA | Posted on October 21st, 2009

JEOL, a global leader in the development and manufacture of scanning and transmission electron microscopes, introduces ClairScopetm, a first-of-its kind correlative microscopy tool that combines a high-end Light Microscope (LM) with a high-resolution Atmospheric Scanning Electron Microscope (ASEM). The new JEOL ClairScope enables uncompromised observation of samples in their native state using both LM and ASEM, significantly reducing sample preparation time and allowing dynamic observation of real time processes. The atmospheric SEM allows high resolution observation of wet biological samples such as cultured cells and imaging of materials samples in liquids.

High Resolution Observation of Life Science and Materials Experiments As They Occur

The ClairScope's unique specimen dish makes it possible to add reagents, drugs, and other substances to the sample in order to perform experiments and observe reactions in both liquid and gas environments. For the first time, life science researchers can harness the powerful imaging capability of the SEM to observe biological processes such as platelet generation, distribution of sugar chains, and microbe growth. Materials scientists will be able to observe and record crystallization, electrochemical reactions, emulsion technology, self-assemblies, and dendrite growth as they occur.

Integrating LM and SEM with Control of Sample Environment

Researchers can control the specimen's environment and stop processes at specific points in the experiment using the ClairScope to observe samples at atmospheric pressure in liquid or gas. The wide-field light microscope with emersion lens is co-axially aligned with the inverted electron column making it easy to switch between the light microscope and the electron microscope without repositioning the specimen dish. The specimen dish features an ultrathin SiN film window that allows transmission of the electron beam for SEM imaging while the sample is open to atmospheric pressure.

"The ClairScope features a high quality wide-field microscope integrated with the ASEM. When we combine SEM and LM, there is no compromise in working distance and there are no issues with vacuum in the ClairScope," said Mitsuo Suga, ClairScope Project Leader.

Atmospheric SEM vs. Environmental SEM

The development of an Atmospheric SEM offers greater opportunities to observe samples in their native state than previously possible. "The advantage of this ASEM over an ESEM is that we can look at samples at room temperature and at atmosphere and we can watch those processes dynamically," said JEOL USA Product Manager Donna Guarrera. "No lengthy drying processes, protective coating, or freezing of wet samples such as cultured cells, is required."

The new ClairScope is being introduced at the Society for Neuroscience meeting in Chicago this week, where more than 30,000 scientists are involved in cutting edge research.

####

About JEOL USA, Inc.
JEOL is a world leader in electron optical equipment and instrumentation for high-end scientific and industrial research and development. Core product groups include electron microscopes (SEMs and TEMs), instruments for the semiconductor industry (electron beam lithography and a series of defect review and inspection tools), and analytical instruments including mass spectrometers, NMRs and ESRs.

JEOL USA, Inc., is a wholly owned subsidiary of JEOL, Ltd., Japan, and was incorporated in the United States in 1962. The company has 13 regional service centers that offer unlimited emergency service and support in the U.S.

For more information about JEOL USA, Inc. or any JEOL products, visit www.jeolusa.com, or call 978-535-5900.

For more information, please click here

Contacts:
Patricia Corkum
978-536-2273

Copyright © JEOL USA, Inc.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Future flexible electronics based on carbon nanotubes: Study in Applied Physics Letters show how to improve nanotube transistor and circuit performance with fluoropolymers September 23rd, 2014

Nanotubes help healing hearts keep the beat: Rice University, Texas Children’s Hospital patch for defects enhances electrical connections between cells September 23rd, 2014

Immune system is key ally in cyberwar against cancer: Rice University study yields new two-step strategy for weakening cancer September 23rd, 2014

Los Alamos Researchers Uncover New Properties in Nanocomposite Oxide Ceramics for Reactor Fuel, Fast-Ion Conductors: Misfit dislocations are key to transport properties across material interfaces September 23rd, 2014

Self Assembly

Big Results Require Big Ambitions: Three young UCSB faculty receive CAREER awards from the National Science Foundation September 18th, 2014

Rice rolls 'neat' nanotube fibers: Rice University researchers' acid-free approach leads to strong conductive carbon threads September 15th, 2014

Molecular self-assembly controls graphene-edge configuration September 10th, 2014

Rice chemist wins rare NSF Special Creativity Award: Grant extension will bolster Zubarev's effort to produce gold nanorods September 8th, 2014

Materials/Metamaterials

Southampton scientists grow a new challenger to graphene September 23rd, 2014

Los Alamos Researchers Uncover New Properties in Nanocomposite Oxide Ceramics for Reactor Fuel, Fast-Ion Conductors: Misfit dislocations are key to transport properties across material interfaces September 23rd, 2014

Engineered proteins stick like glue — even in water: New adhesives based on mussel proteins could be useful for naval or medical applications September 22nd, 2014

New star-shaped molecule breakthrough: Scientists at The University of Manchester have generated a new star-shaped molecule made up of interlocking rings, which is the most complex of its kind ever created September 22nd, 2014

Announcements

Future flexible electronics based on carbon nanotubes: Study in Applied Physics Letters show how to improve nanotube transistor and circuit performance with fluoropolymers September 23rd, 2014

Nanotubes help healing hearts keep the beat: Rice University, Texas Children’s Hospital patch for defects enhances electrical connections between cells September 23rd, 2014

Immune system is key ally in cyberwar against cancer: Rice University study yields new two-step strategy for weakening cancer September 23rd, 2014

Los Alamos Researchers Uncover New Properties in Nanocomposite Oxide Ceramics for Reactor Fuel, Fast-Ion Conductors: Misfit dislocations are key to transport properties across material interfaces September 23rd, 2014

Tools

IEEE International Electron Devices Meeting To Celebrate 60th Anniversary as The Leading Technical Conference for Advanced Semiconductor Devices September 18th, 2014

FEI Opens New Technology Center in Czech Republic: FEI expands its presence in Brno with the opening of a new, larger facility September 18th, 2014

New NPZ100-403 Piezo Stage from nPoint Inc. September 17th, 2014

Researchers Create World’s Largest DNA Origami September 11th, 2014

Nanobiotechnology

Production of Organometallic Frameworks in Least Possible Time September 23rd, 2014

New star-shaped molecule breakthrough: Scientists at The University of Manchester have generated a new star-shaped molecule made up of interlocking rings, which is the most complex of its kind ever created September 22nd, 2014

Arrowhead to Present at BioCentury's NewsMakers in the Biotech Industry Conference September 19th, 2014

CiQUS researchers design an artificial nose to detect DNA differentiation with single nucleotide resolution September 18th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE