Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > News > Topical Cream for Erectile Dysfunction Shows Promise: It could become alternative for men who can't tolerate pills, researchers say

September 19th, 2009

Topical Cream for Erectile Dysfunction Shows Promise: It could become alternative for men who can't tolerate pills, researchers say

Abstract:
A topical cream for erectile dysfunction shows promise in animal testing and could become an alternative for men who can't tolerate the pill form of the drugs, U.S. researchers report.

Oral erectile dysfunction (ED) drugs, which belong to a class of medications called phosphodiesterase 5 (PDE5) inhibitors, are widely used and highly effective but can cause such side effects as headache, upset stomach, nasal congestion, facial flushing and hearing and vision problems. Men who've recently had a heart attack or have severe heart disease have to use oral ED drugs with caution, if at all.

The new cream consists of nanoparticles that can carry drugs or other substances, such as nitric oxide, and deliver them in a controlled and sustained manner, according to the researchers, who are from Albert Einstein College of Medicine at Yeshiva University in New York City. Nitric oxide is the signaling molecule that dilates blood vessels responsible for creating an erection.

The nanoparticle therapy was tested on 18 rats bred to have age-related ED. Some rats received nanoparticles with nitric oxide, others received nanoparticles with nitric oxide plus an experimental ED drug called silorphin (which has a different mechanism of action than PDE5 inhibitors) and a third group of rats received nanoparticles with nitric oxide and the PDE5 inhibitor tadalafil (Cialis).

Source:
healthday.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

A 'movie' of ultrafast rotating molecules at a hundred billion per second: A quantum wave-like nature was successfully observed in rotating nitrogen molecules July 4th, 2015

New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment July 4th, 2015

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Pioneering Southampton scientist awarded prestigious physics medal July 3rd, 2015

Nanomedicine

New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment July 4th, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Iranian Scientists Find Simple, Economic Method to Synthesize Antibacterial Nanoparticles July 2nd, 2015

Leti Announces Launch of First European Nanomedicine Characterisation Laboratory: Project Combines Expertise of 9 Partners in 8 Countries to Foster Nanomedicine Innovation and Facilitate Regulatory Approval July 1st, 2015

Discoveries

A 'movie' of ultrafast rotating molecules at a hundred billion per second: A quantum wave-like nature was successfully observed in rotating nitrogen molecules July 4th, 2015

New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment July 4th, 2015

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015

Announcements

A 'movie' of ultrafast rotating molecules at a hundred billion per second: A quantum wave-like nature was successfully observed in rotating nitrogen molecules July 4th, 2015

New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment July 4th, 2015

Clues to inner atomic life from subtle light-emission shifts: Hyperfine structure of light absorption by short-lived cadmium atom isotopes reveals characteristics of the nucleus that matter for high precision detection methods July 3rd, 2015

Pioneering Southampton scientist awarded prestigious physics medal July 3rd, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project