Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > A "Super Sensor" for Cancer and CSI's

Abstract:
TAU develops tiny device to "sniff out" disease, heart attacks, poison and environmental pollution

A "Super Sensor" for Cancer and CSI's

Tel Aviv, Israel | Posted on August 10th, 2009

Like the sensitive seismographs that can pick up tremors of impending earthquakes long before they strike, a similar invention from Tel Aviv University researchers may change the face of molecular biology.

Coupling biological materials with an electrode-based device, Prof. Judith Rishpon of TAU's Department of Molecular Microbiology and Biotechnology is able to quickly and precisely detect pathogens and pollution in the environment and infinitesimally small amounts of disease biomarkers in our blood. About the size of a stick of gum, the new invention may be applied to a wide range of environments and situations. The aim is for the device to be disposable and cost about $1.

"Biosensors are important for the bio-terror industry, but are also critical for detecting pathogens in water, for the food industry, and in medical diagnostics," says Prof. Rishpon. Her latest research appeared in the journals Nanomedicine: Nanotechnology Biology and Medicine, Electroanalysis and Bioelectrochemistry.

Portable and precise

What makes this particular invention particularly appealing is its small size and the fact that it can be easily connected to a handheld device like a Blackberry or iPhone for quick and reliable results. An electrical signal will pulse "yes" for the presence of a test molecule and a "no" for its absence.

Currently, clinical researchers are testing its application in cancer diagnostics, focusing on the detection of proteins associated with colon and brain cancer and efficacy of anticancer drugs. But the device is capable of detecting various types of substances. "It really depends on what you put at the end of the electrode," says Prof. Rishpon.

"You can put enzymes, antibodies or bacteria on my electrodes to sense the existence of a chemical target. Then we can measure the amount of the target, assessing its potency by using additional enzymes or by looking at the changes of the electrochemical properties on the device," she says.

An early warning system for heart attacks

Enzymes released before the onset of a heart attack can also be detected, so this application has obvious uses in an operating room to give a physician warning of an impending attack during a procedure. It could be fitted into an implant like a pacemaker or another future device to alert the user to impending dangers, thus preventing sudden death.

Prof. Rishpon is also investigating the application of her technology to detect for pathogens in drinking water such as estrogen, a byproduct of the female birth control pill. The presence of these chemicals in America's drinking water is no minor health concern. And before tackling the problem, water officials need to know what they are up against. Prof. Rishpon's solution could be part of the future toolkit, she believes.

A bio-watchdog for the organic food industry

Detecting pesticides in food is another very desirable application. The organic food market is calling for more rigorous testing and regulations to ensure spraying doesn't occur on some farms, and that limits are not breached on others.

Commercial applications of Prof. Rishpon's basic research are already underway in many areas of diagnostics, but clearly there are more to come. "My super sensors are cheap, accurate and highly sensitive, and in principle they could detect and measure the presence of almost every biological-based material," Dr. Rishpon concludes. She is also collaborating on the device with scientists at Arizona State University.

####

About American Friends of Tel Aviv University
Tel Aviv University's American Friends are a worldly and intellectually sophisticated group, committed to nurturing higher education and developing Israel's best minds.

For more information, please click here

Contacts:
NATIONAL OFFICE
39 Broadway, Suite 1510
New York, NY 10006
Tel: 212.742.9070 or 800.989.1198
Fax: 212.742.9071

Copyright © American Friends of Tel Aviv University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Marketplace Rule 5635(c)(4) September 25th, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

Possible Futures

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Marketplace Rule 5635(c)(4) September 25th, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

Nanomedicine

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Marketplace Rule 5635(c)(4) September 25th, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

Sensors

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Leti Announces EU Project to Develop Powerful, Inexpensive Sensors with Photonic Integrated Circuits: REDFINCH Members Initially Targeting Applications for Gas Detection and Analysis For Refineries & Petrochemical Industry and Protein Analysis for Dairy Industry September 19th, 2018

Rice U. lab probes molecular limit of plasmonics: Optical effect detailed in organic molecules with fewer than 50 atoms September 5th, 2018

Measuring the nanoworld September 4th, 2018

Announcements

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Marketplace Rule 5635(c)(4) September 25th, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

Food/Agriculture/Supplements

Leti Announces EU Project to Develop Powerful, Inexpensive Sensors with Photonic Integrated Circuits: REDFINCH Members Initially Targeting Applications for Gas Detection and Analysis For Refineries & Petrochemical Industry and Protein Analysis for Dairy Industry September 19th, 2018

Research brief: UMN researchers use green gold to rapidly detect and identify harmful bacteria August 15th, 2018

Changing the grocery game: Manufacturing process provides low-cost, sustainable option for food packaging June 26th, 2018

Nanomaterials could mean more algae outbreaks for wetlands, waterways: High tech metal particles may inadvertently take a toll on aquatic life June 26th, 2018

Environment

Silver nanoparticles are toxic for aquatic organisms: A research team at the UPV/EHU-University of the Basque Country has analysed how zebrafish are affected in the long term by exposure to silver particles September 19th, 2018

Carbon nanodots do an ultrafine job with in vitro lung tissue: New experiments highlight the role of charge and size when it comes to carbon nanodots that mimic the effect of nanoscale pollution particles on the human lung. September 12th, 2018

A human enzyme can biodegrade graphene August 28th, 2018

Large scale preparation method of high quality SWNT sponges August 24th, 2018

Nanobiotechnology

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals to Host R&D Day on Emerging Pipeline of RNAi Therapeutics September 25th, 2018

Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Marketplace Rule 5635(c)(4) September 25th, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project