Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Integrated optical trap holds particles for on-chip analysis

Abstract:
A new type of optical particle trap can be used to manipulate bacteria, viruses and other particles on a chip as part of an integrated optofluidic platform. The optical trap is the latest innovation from researchers at the Jack Baskin School of Engineering at the University of California, Santa Cruz, who are developing new sensor technology for biomedical analysis and other applications.

Integrated optical trap holds particles for on-chip analysis

Santa Cruz, CA | Posted on June 30th, 2009

"Ultimately, it could have applications for rapid detection of bacteria and viruses in hospitals, for cell sorting in research labs, and for process monitoring in chemical engineering," said Holger Schmidt, professor of electrical engineering and director of the W. M. Keck Center for Nanoscale Optofluidics at UCSC.

The new technique offers the potential to create a smaller, cheaper version of the sophisticated equipment used to perform fluorescence-activated cell sorting (FACS), Schmidt said.

"The capabilities of our optofluidic platform are continuing to grow. We have gone from the detection of single molecules and single viruses to now being able to control the movement of particles," he said.

Schmidt's group has received a $400,000 grant from the National Institutes of Health to explore particle trapping and sorting and other applications of the optofluidics platform. An article describing the optical trap for on-chip particle analysis has been published online by the journal *Lab on a Chip*. First author Sergei Kuhn was a postdoctoral researcher in Schmidt's lab and is now at the Max-Born Institute in Berlin. Coauthors include David Deamer and Philip Measor at UCSC and E. J. Lunt, B. S. Phillips, and A. R. Hawkins of Brigham Young University, where the optofluidic chips are fabricated.

Optical traps and "optical tweezers" use the momentum carried by the photons in a beam of light to exert forces on microscopic objects, enabling researchers to manipulate objects ranging from biological molecules to living cells. Schmidt's group developed a new way to perform optical trapping on a chip-based platform.

The technique relies on an earlier innovation from Schmidt's lab: a hollow-core optical waveguide that can direct a beam of light through a liquid-filled channel on a chip. To trap particles, the researchers used two laser beams at opposite ends of a channel. A particle gets trapped at the point where the forces exerted by the two beams are equal, and the particle can be moved by changing the relative power of the two laser beams.

"We can also use this like an optical leaf blower to push all the particles in a sample to the same spot and increase the concentration," Schmidt said.

"The goal is to control the position and movement of particles through channels on a chip so they can be studied using fluorescence analysis and other optical methods."

####

About UCSC
The Jack Baskin School of Engineering at UCSC prepares technologists--and sponsors technology--for our changing world. Founded in 1997, Baskin Engineering trains students in six future-focused areas of engineering: biotechnology/information technology/nanotechnology; information and communication infrastructure; mathematical and statistical modeling; software and services engineering; system design; and bioengineering. Baskin Engineering faculty conduct industry-leading research that is improving the way the world does business, treats the environment, and nurtures humanity.

For more information, please click here

Contacts:
Tim Stephens
(831) 459-2495

Copyright © UCSC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

PETA science consortium to present hazard testing strategy at nanotoxicology meeting: High tech field ripe for use of sophisticated non-animal testing strategies April 22nd, 2014

Harris & Harris Group Notes the Receipt of Proceeds From the Sale of Molecular Imprints' Semiconductor Business to Canon April 22nd, 2014

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

Possible Futures

Virus structure inspires novel understanding of onion-like carbon nanoparticles April 10th, 2014

Local girl does good March 22nd, 2014

Surface Characteristics Influence Cellular Growth on Semiconductor Material March 12th, 2014

The "Tipping Point" February 12th, 2014

Nanomedicine

Cloaked DNA nanodevices survive pilot mission: Successful foray opens door to virus-like DNA nanodevices that could diagnose diseased tissues and manufacture drugs to treat them April 22nd, 2014

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

Amino-functionalized carbon nanotubes act as a carrier for nerve growth factor April 21st, 2014

Newly-Produced Bone Cement Able to Carry Medicine April 21st, 2014

Announcements

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

PETA science consortium to present hazard testing strategy at nanotoxicology meeting: High tech field ripe for use of sophisticated non-animal testing strategies April 22nd, 2014

Harris & Harris Group Notes the Receipt of Proceeds From the Sale of Molecular Imprints' Semiconductor Business to Canon April 22nd, 2014

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

Energy Research Facility Construction Project at Brookhaven Lab Wins U.S. Energy Secretary's Achievement Award April 16th, 2014

IDTechEx Printed Electronics Europe 2014 Award Winners April 1st, 2014

Dais Analytic Wins SBIR Grant: Dais Analytic Receives US Army Small Business Innovation Research Grant to Further Its Demonstrated Successes in Cleaning Most Forms of Wastewater March 28th, 2014

Nanobiotechnology

Cloaked DNA nanodevices survive pilot mission: Successful foray opens door to virus-like DNA nanodevices that could diagnose diseased tissues and manufacture drugs to treat them April 22nd, 2014

Targeting cancer with a triple threat: MIT chemists design nanoparticles that can deliver three cancer drugs at a time April 15th, 2014

Biologists Develop Nanosensors to Visualize Movements and Distribution of Plant Stress Hormone April 15th, 2014

In latest generation of tiny biosensors, size isn't everything: UCLA researchers overturn conventional wisdom on nanowire-based diagnostic devices April 11th, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE