Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button

Home > Press > Mathematical Model Predicts Factors Driving Tumor Invasion (special interest story)

Abstract:
Tumors are complex collections of cells whose behavior has proven difficult to understand, let alone predict. As a result, oncologists are often surprised by how a particular patient responds to a given course of therapy.

Enter mathematics. Using a sophisticated mathematical model that relates a wide variety of biological variables to disease progression, a research team headed by Vittorio Cristini, Ph.D., and Mauro Ferrari, Ph.D., the University of Texas Health Science Center in Houston, and David B. Agus, M.D., the University of Southern California and the Center for Cancer Nanotechnology Excellence Focused on Therapy Response, has shown that accounting for the shape and physical characteristics of the tumor margin and invasiveness of the tumor accurately predicts how a particular tumor will develop and metastasize. The results of this study appear in the journal Cancer Research.

Mathematical Model Predicts Factors Driving Tumor Invasion (special interest story)

Bethesda, MD | Posted on June 27th, 2009

One of the major findings of this study is that tumor progression is not a random process, but rather one that responds predictably based on well-established biophysical laws, genetic effects, and the microenvironment surrounding a tumor, among other factors. The model predicts that different tumor morphologies—the shapes and structural features of a given tumor—influence a tumor's ability to infiltrate otherwise healthy tissue in a predictable manner. Tumor morphology is determined as part of the standard procedures used to characterize tumors from tissue biopsies.

The researchers note that this model may provide new insights into how a tumor is perturbed by various therapies. If so, this model could prove useful in designing new clinical endpoints in therapeutic trials and ultimately in predicting patient response to a given therapy based on the unique physical characteristics of that patient's disease.

####

About
To help meet the goal of reducing the burden of cancer, the National Cancer Institute (NCI), part of the National Institutes of Health, is engaged in efforts to harness the power of nanotechnology to radically change the way we diagnose, treat and prevent cancer.

The NCI Alliance for Nanotechnology in Cancer is a comprehensive, systematized initiative encompassing the public and private sectors, designed to accelerate the application of the best capabilities of nanotechnology to cancer.

Currently, scientists are limited in their ability to turn promising molecular discoveries into benefits for cancer patients. Nanotechnology can provide the technical power and tools that will enable those developing new diagnostics, therapeutics, and preventives to keep pace with today’s explosion in knowledge.

For more information, please click here

Contacts:
National Cancer Institute
Office of Technology & Industrial Relations
ATTN: NCI Alliance for Nanotechnology in Cancer
Building 31, Room 10A49
31 Center Drive , MSC 2580
Bethesda , MD 20892-2580

Copyright © National Cancer Institute

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

View abstract - “Multiparameter computational modeling of tumor invasion.”

Related News Press

News and information

Starpharma initiates new DEP™ drug delivery program with AstraZeneca July 27th, 2016

Ageing can drive progress: Population ageing is likely to boost medicine, nanotechnology and robotics, but increase political risks July 27th, 2016

WSU researchers 'watch' crystal structure change in real time: Breakthrough made possible by new Argonne facility July 27th, 2016

Enhancing molecular imaging with light: New technology platform increases spectroscopic resolution by 4 fold July 27th, 2016

Govt.-Legislation/Regulation/Funding/Policy

WSU researchers 'watch' crystal structure change in real time: Breakthrough made possible by new Argonne facility July 27th, 2016

Enhancing molecular imaging with light: New technology platform increases spectroscopic resolution by 4 fold July 27th, 2016

New nontoxic process promises larger ultrathin sheets of 2-D nanomaterials July 27th, 2016

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Nanomedicine

Starpharma initiates new DEP™ drug delivery program with AstraZeneca July 27th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

The NanoWizard® AFM from JPK is applied for interdisciplinary research at the University of South Australia for applications including smart wound healing and how plants can protect themselves from toxins July 26th, 2016

Accurate design of large icosahedral protein nanocages pushes bioengineering boundaries: Scientists used computational methods to build ten large, two-component, co-assembling icosahedral protein complexes the size of small virus coats July 25th, 2016

Discoveries

WSU researchers 'watch' crystal structure change in real time: Breakthrough made possible by new Argonne facility July 27th, 2016

Enhancing molecular imaging with light: New technology platform increases spectroscopic resolution by 4 fold July 27th, 2016

New nontoxic process promises larger ultrathin sheets of 2-D nanomaterials July 27th, 2016

Ultrasensitive sensor using N-doped graphene July 26th, 2016

Announcements

Starpharma initiates new DEP™ drug delivery program with AstraZeneca July 27th, 2016

Ageing can drive progress: Population ageing is likely to boost medicine, nanotechnology and robotics, but increase political risks July 27th, 2016

WSU researchers 'watch' crystal structure change in real time: Breakthrough made possible by new Argonne facility July 27th, 2016

Enhancing molecular imaging with light: New technology platform increases spectroscopic resolution by 4 fold July 27th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic