Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nanoscopic "Pearl Necklaces" Track and Attack Cancer Cells

Abstract:
A team of investigators at Purdue University has developed nanoscale probes that can help pinpoint the location of tumors and might one day be able to directly attack cancer cells. Joseph Irudayaraj, Ph.D., led the team that developed the tumor-targeting multifunctional probes. "If we have a tumor, these probes should have the ability to latch on to it," Dr. Irudayaraj said. "The probe could carry drugs to target, treat, and reveal cancer cells." This study appears in the journal Angewandte Chemie International Edition.

Nanoscopic "Pearl Necklaces" Track and Attack Cancer Cells

Bethesda, MD | Posted on April 27th, 2009

Researchers have developed probes that use either gold nanorods or magnetic iron oxide nanoparticles, but Dr. Irudayaraj's nanoprobes use both, making them easier to track with different imaging devices as they move toward cancer cells. The magnetic iron oxide particles can be traced using magnetic resonance imaging (MRI), whereas the gold nanorods are luminescent and can be traced through microscopy, a more sensitive and precise process. Dr. Irudayaraj noted that an MRI is less precise than optical luminescence in tracking the probes but has the advantage of being able to track them deeper in tissue, expanding the probes' possible applications. The gold nanorods act as the "string," while the iron oxide nanoparticles, which are linked to the nanorods, serve as the "pearls."

The probes contain the antibody herceptin, which is used in the treatment of metastatic breast cancer. Experiments demonstrated that these probes targeted and were taken up by cultured breast cancer cells expressing the Her-2 protein. The investigators also showed that the nanoprobes, when illuminated with near-infrared light, could serve as photothermal anticancer agents. The investigators are now working to add additional anticancer agents to these nanoscale constructs.

####

About National Cancer Institute
To help meet the goal of reducing the burden of cancer, the National Cancer Institute (NCI), part of the National Institutes of Health, is engaged in efforts to harness the power of nanotechnology to radically change the way we diagnose, treat and prevent cancer.

The NCI Alliance for Nanotechnology in Cancer is a comprehensive, systematized initiative encompassing the public and private sectors, designed to accelerate the application of the best capabilities of nanotechnology to cancer.

Currently, scientists are limited in their ability to turn promising molecular discoveries into benefits for cancer patients. Nanotechnology can provide the technical power and tools that will enable those developing new diagnostics, therapeutics, and preventives to keep pace with today’s explosion in knowledge.

For more information, please click here

Contacts:
National Cancer Institute
Office of Technology & Industrial Relations
ATTN: NCI Alliance for Nanotechnology in Cancer
Building 31, Room 10A49
31 Center Drive , MSC 2580
Bethesda, MD 20892-2580

Copyright © National Cancer Institute

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

“Gold nanorod/Fe3O4 nanoparticle ‘nano-pearl-necklaces’ for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells.”

Related News Press

News and information

University of Tehran Researchers Invent Non-Enzyme Sensor to Detect Blood Sugar April 23rd, 2014

Gold nanoparticles help target, quantify breast cancer gene segments in a living cell April 23rd, 2014

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Govt.-Legislation/Regulation/Funding/Policy

Gold nanoparticles help target, quantify breast cancer gene segments in a living cell April 23rd, 2014

Atomic switcheroo explains origins of thin-film solar cell mystery April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

Nanomedicine

University of Tehran Researchers Invent Non-Enzyme Sensor to Detect Blood Sugar April 23rd, 2014

Gold nanoparticles help target, quantify breast cancer gene segments in a living cell April 23rd, 2014

QuantuMDx announce prototype handheld lab for 15 minute malaria diagnosis and drug resistance testing April 23rd, 2014

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

Announcements

Characterizing inkjet inks: Malvern Instruments presents new rheological research April 23rd, 2014

NanoSafe, Inc. announces the addition of the Labconco Protector® Glove Box to its NanoSafe Tested™ registry April 23rd, 2014

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE