Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Connecting materials science with biology, K-State engineers create DNA sensors that could identify cancer using material only one atom thick

Abstract:
Kansas State University engineers think the possibilities are deep for a very thin material.

Vikas Berry, assistant professor of chemical engineering, is leading research combining biological materials with graphene, a recently developed carbon material that is only a single atom thick.

Connecting materials science with biology, K-State engineers create DNA sensors that could identify cancer using material only one atom thick

MANHATTAN, KS | Posted on April 13th, 2009

"The biological interfacing of graphene is taking this material to the next level," Berry said. "Discovered only four years ago, this material has already shown a large number of capabilities. K-Staters are the first to do bio-integrated research with graphene."

To study graphene, researchers rely on an atomic force microscope to help them observe and manipulate these single atom thick carbon sheets.

"It's a fascinating material to work with," Berry said. "The most significant feature of graphene is that the electrons can travel without interruptions at speeds close to that of light at room temperature. Usually you have to go near zero Kelvin -- that's about 450 degrees below zero Fahrenheit -- to get electrons to move at ultra high speeds."

One of Berry's developments is a graphene-based DNA sensor. When electrons flow on the graphene, they change speed if they encounter DNA. The researchers notice this change by measuring the electrical conductivity. The work was published in Nano-Letters.

"Most DNA sensors are optical, but this one is electrical," Berry said. "We are currently collaborating with researchers from Harvard Medical School to sense cancer cells in blood."

Another area he is exploring is loading graphene with antibodies and flowing bacteria across the surface.

"Most researchers focus on pristine graphene, but we're making it dirty," he said.

Berry and Nihar Mohanty, a graduate student in chemical engineering, used a type of bacteria commonly found in rice and interfaced it with graphene. They found that the graphene with tethered antibodies will wrap itself around an individual bacterium, which remains alive for 12 hours.

Berry said that possible applications include a high-efficiency bacteria-operated battery, where by using geobater, a type of bacteria known to produce electrons, can be wrapped with graphene to produce electricity. The research was presented at the annual American Physical Society conference in Pittsburgh and the American Institute for Chemical Engineers conference in Philadelphia.

"Materials science is an incredible field with several exploitable quantum effects occurring at molecular scale, and biology is a remarkable field with a variety of specific biochemical mechanisms," Berry said. "But for the most part the two fields are isolated. If you join these two fields, the possibilities are going to be immense. For example, one can think of a bacterium as a machine with molecular scale components and one can exploit the functioning of those components in a material device."

For his doctoral research, Berry used bacteria to make a humidity sensor.

"That was only possible through combining materials science with biological science," he said.

Another area of his current research is compressing and stretching molecular-junctions between nanoparticles. Berry said that his group has developed a molecular-spring device where they can compress and stretch molecules, which then act like springs, allowing researchers to study how they relax back. He said that this technology could be used to create molecular-timers in which the spring action from a decompressed molecule on a chip could trigger a circuit, for instance.

Berry said for stretching the molecules, Kabeer Jasuja, a doctoral student in chemical engineering, came up with the idea to place the device on a centrifuge to stretch the molecules with centrifugal force.

The work was published in the journal Small.

####

For more information, please click here

Contacts:
Source:
Vikas Berry
785-532-5519


News release prepared by:
Erinn Barcomb-Peterson
785-532-6415

Copyright © Kansas State University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists produce 3D chemical maps of single bacteria: Researchers at NSLS-II used ultrabright x-rays to generate 3-D nanoscale maps of a single bacteria's chemical composition with unparalleled spatial resolution November 16th, 2018

Bosch provides customized IoT and Industry 4.0 solutions: Bosch Mondeville and Bosch Connected Devices and Solutions collaborate to meet a wide variety of customer requirements November 16th, 2018

GaN Rising: UC Santa Barbara electrical and computer engineering professor Umesh Mishra to deliver 63rd Annual Faculty Research Lecture November 16th, 2018

Nanometrics Completes Acquisition of 4D Technology Corporation: The addition of Dynamic Interferometry® expands process control technology solutions November 16th, 2018

Nanomedicine

Scientists produce 3D chemical maps of single bacteria: Researchers at NSLS-II used ultrabright x-rays to generate 3-D nanoscale maps of a single bacteria's chemical composition with unparalleled spatial resolution November 16th, 2018

Arrowhead Pharmaceuticals Presents Late-Breaking Clinical Data on ARO-AAT at Liver Meeting® 2018 November 9th, 2018

Arrowhead Pharmaceuticals Presents Late-Breaking Preliminary Clinical Data on ARO-HBV at Liver Meeting® 2018 November 9th, 2018

WSU researchers develop new technique to understand biology at the nanoscale November 7th, 2018

Sensors

Bosch provides customized IoT and Industry 4.0 solutions: Bosch Mondeville and Bosch Connected Devices and Solutions collaborate to meet a wide variety of customer requirements November 16th, 2018

European Commission Project Creates Pilot Line for Companies to Develop Mid-Infrared Devices: Companies Can Submit Proposals for Possible Matching Funds To Help Develop Prototypes November 13th, 2018

Mode-Changing MEMS Accelerometer from STMicroelectronics Combines High Measurement Resolution and Ultra-Low Power for Industrial Applications November 7th, 2018

Nanotech Artisans Sculpt with DNA November 5th, 2018

Discoveries

Scientists produce 3D chemical maps of single bacteria: Researchers at NSLS-II used ultrabright x-rays to generate 3-D nanoscale maps of a single bacteria's chemical composition with unparalleled spatial resolution November 16th, 2018

'Smart skin' simplifies spotting strain in structures: Rice U. invention can use fluorescing carbon nanotubes to reveal stress in aircraft, structures November 15th, 2018

Epoxy compound gets a graphene bump: Rice scientists combine graphene foam, epoxy into tough, conductive composite November 14th, 2018

Optimization of alloy materials: Diffusion processes in nano particles decoded November 13th, 2018

Announcements

Scientists produce 3D chemical maps of single bacteria: Researchers at NSLS-II used ultrabright x-rays to generate 3-D nanoscale maps of a single bacteria's chemical composition with unparalleled spatial resolution November 16th, 2018

Bosch provides customized IoT and Industry 4.0 solutions: Bosch Mondeville and Bosch Connected Devices and Solutions collaborate to meet a wide variety of customer requirements November 16th, 2018

GaN Rising: UC Santa Barbara electrical and computer engineering professor Umesh Mishra to deliver 63rd Annual Faculty Research Lecture November 16th, 2018

Nanometrics Completes Acquisition of 4D Technology Corporation: The addition of Dynamic Interferometry® expands process control technology solutions November 16th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project