Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Colorado State University Professor Exploring Chemotherapy, Drug Delivery to Tissues Via Tiny Nanotubes on Titanium Implants

Cell growth on polymer wires made at CSU
Cell growth on polymer wires made at CSU

Abstract:
A Colorado State University mechanical engineering professor is in the first year of a new study to determine whether nanotubes on titanium implants can deliver chemotherapy drugs and antibiotics directly to skeletal implants, limiting the spread of drugs throughout the body and reducing side effects on patients.

Colorado State University Professor Exploring Chemotherapy, Drug Delivery to Tissues Via Tiny Nanotubes on Titanium Implants

Fort Collins, CO | Posted on April 7th, 2009

Ketul Popat, who teaches in the university's School of Biomedical Engineering, received a three-year $300,000 grant in 2008 from the National Science Foundation to study nanomedicine - scaling down the size of drug delivery vehicles so that the drugs can be delivered directly to the target organs with appropriate delivery rates. One of the first papers on the study appeared in the January issue of Nanotechnology magazine.

Colorado's Bioscience Discovery Evaluation Program, which aims to foster development of the bioscience industry in the state, also recently approved a grant of $57,000 for the research.

Popat and his four students are investigating whether tiny tubes of titanium adhered to the implant can be used to deliver drugs and increase bone growth on the implant surface. Titanium, which is an exceptionally hard and scratch-resistant material, has been used in prosthetic devices since the 1970s. Popat's team is taking the research to the next level: Will increasing the surface area of the titanium with a pattern of tiny tubes allow drugs to be delivered in a controlled way that will help regenerate the bone and keep the tissue healthy?

"We hope these nanotube arrays will mimic the complex geometries of natural tissue and will provide a porous mesh for the growth and maintenance of healthy cells," Popat said.

Popat said his team has hypothesized that applying nanotubes to the implant surface will result in increased cell growth. This cell growth on the implant surface will enhance the bond between the titanium implant and the bone, helping implants last longer. Typically implants must be replaced every eight to 10 years. However, by applying these nanotubes to the implant, they can be made more permanent inside the body, thus preventing further complicated surgeries in patients.

"Ultimately, if this kind of drug delivery system is found to be successful, it's going to improve the quality of life for people," Popat said. "Chemotherapy delivers up to 60 times more drugs than what is needed. We could release the drug for shorter or longer periods of time and keep the drug targeted to the tissue where is it needed so you won't realize you're taking a drug and there won't be any side effects."

Popat joined the Colorado State University College of Engineering in January 2008 as an assistant professor. He is working with Craig Grimes at Pennsylvania State University on the research.

Note to Editors: Photos of Professor Ketul Popat and his laboratory can be found with the news release at http://www.newsinfo.colostate.edu/.

####

About Colorado State University
Colorado State University is one of our nation's leading research universities with world-class research in infectious disease, atmospheric science, clean energy technologies, and environmental science. It was founded in 1870 as the Colorado Agricultural College, six years before the Colorado Territory became a state.

Last year, CSU awarded degrees to more than 5,000 graduates, and this year, it attracted nearly $300 million in research funding. Colorado State is a land-grant institution and a Carnegie Doctoral/Research University-Extensive.

Colorado State University is the “university of choice” for Colorado residents – 30% of all of Colorado's science, math, engineering and technology majors pursue degrees at CSU. In addition to its excellent programs in those areas, CSU offers among the very best professional programs in the United States in veterinary medicine, occupational therapy, journalism, agriculture and construction management.

For more information, please click here

Contacts:
Contact for Reporters:
Emily Narvaes Wilmsen
(970) 491-2336

Copyright © Colorado State University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

JPK reports on the use of AFM and the CellHesion module to study plant cells at the University of Queensland November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Govt.-Legislation/Regulation/Funding/Policy

Lawrence Livermore researchers develop efficient method to produce nanoporous metals November 25th, 2014

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Possible Futures

A novel method for identifying the body’s ‘noisiest’ networks November 19th, 2014

Researchers discern the shapes of high-order Brownian motions November 17th, 2014

VDMA Electronics Production Equipment: Growth track for 2014 and 2015 confirmed: Business climate survey shows robust industry sector November 14th, 2014

Open Materials Development Will Be Key for HP's Success in 3D Printing: HP can make a big splash in 3D printing, but it needs to shore up technology claims and avoid the temptation of the razor/razor blade business model in order to flourish November 11th, 2014

Nanotubes/Buckyballs

Tesla NanoCoatings Increasing Use of SouthWest NanoTechnologies Carbon Nanotubes (CNTs) for its Infrastructure Coatings and Paints: High Quality SMW™ Specialty Multi-wall Carbon Nanotubes Incorporated into Teslan®-brand coatings used by Transportation, Oil and Gas Companies November 19th, 2014

Graphene/nanotube hybrid benefits flexible solar cells: Rice University labs create novel electrode for dye-sensitized cells November 17th, 2014

SouthWest NanoTechnologies to Demonstrate 3D Capacitive Touch Sensor Featuring Transparent, Thermoformed Carbon Nanotube Ink at Printed Electronics USA 2014 (Booth J25) -- “Conductive and Semiconducting Single-Wall Carbon Nanotube Inks” will be Topic of Company Presentation November 10th, 2014

Neural Canals Produced in Iran for Recovery of Sciatica Nerve November 8th, 2014

Nanomedicine

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research reveals how our bodies keep unwelcome visitors out of cell nuclei November 24th, 2014

ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality November 24th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Announcements

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

JPK reports on the use of AFM and the CellHesion module to study plant cells at the University of Queensland November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

A*STAR SIMTech wins international award for breaking new ground in actuators: SIMTech invention can be used in an array of industries, and is critical for next generation ultra-precision systems November 24th, 2014

SUNY Poly Student Awarded Fellowship with the U.S. Department of Energy's Postgraduate Research Program: Ph.D. Candidate Accepts Postmaster's Appointment To Conduct Research At Albany NanoTech Complex November 13th, 2014

MEMS Industry Group's 10th Annual Executive Conference Showcases Rapid Innovation in MEMS/Sensors: Emphasizes Spirit of Collaboration, Supporting First Open-Source Algorithm Community, New Standardization Efforts November 10th, 2014

Nanobiotechnology

Quantum mechanical calculations reveal the hidden states of enzyme active sites November 20th, 2014

Tokyo Institute of Technology research: Protein-engineered cages aid studies of cell functions November 19th, 2014

A novel method for identifying the body’s ‘noisiest’ networks November 19th, 2014

Implementation of DNA Chains in Designing Nanospin Pieces November 9th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE