Nanotechnology Now

Our NanoNews Digest Sponsors







Heifer International

Wikipedia Affiliate Button


Home > News > White light microscope

March 1st, 2009

White light microscope

Abstract:
Silver nanoparticles that can generate white light could improve microscopy in research into cancer and bone diseases according to a paper in the March issue of Nano Letters.

Optical microscopy is commonly thought to use optical transmission measurements, whereas most modern microscopists working with contemporary high-resolution microscopes use fluorescence. But, fluorescence has its limitations.

Powerful as it is, fluorescence microscopy has a fatal flaw - the need to treat any specimen with fluorescent dyes or stains. The application of these dyes often alters or harms tissues and can kill living cells. So, although fluorescence microscopy is unsurpassed in acquisition speed and spatial resolution it is severely limited in this sense.

John Lupton and colleagues, Debansu Chaudhuri, Jeremy Galushs, Manfred Walter, Nicholas Borys, and Michael Bartl in the Department of Physics and Department of Chemistry, at the University of Utah, Salt Lake City, hope to circumvent this problem without resorting to old-style microscopy.

They have worked clusters of silver nanoparticles. Silver nanoparticle films have been used for single molecule surface-enhanced Raman scattering (SERS) studies before with one- or two-photon excitation. They can thus act as a tuneable beacon of light for transmission microscopy carried out at resolutions below the diffraction limit. This limit normally stymies conventional microscopy. The researchers suggest that their success could allow researchers to investigate cancerous tissues, diseased bone and other diffuse materials in unprecedented detail and without dyes to damage the sample.

Source:
spectroscopynow.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

How do cold ions slide May 24th, 2013

Heinrich Rohrer dies at 79; a father of nanotechnology: With IBM colleague Gerd Binnig, Rohrer invented the scanning tunneling microscope, which can show individual atoms on a surface and move them around May 23rd, 2013

Gold nanocrystal vibration captured on billion-frames-per-second film May 23rd, 2013

Glowing Plant Releases Maker Kit, Enabling Anyone to Make a Glowing Plant at Home: Glowing Plant seeks funds via crowdfunding and raises almost $400,000 May 23rd, 2013

Imaging

Heinrich Rohrer dies at 79; a father of nanotechnology: With IBM colleague Gerd Binnig, Rohrer invented the scanning tunneling microscope, which can show individual atoms on a surface and move them around May 23rd, 2013

Gold nanocrystal vibration captured on billion-frames-per-second film May 23rd, 2013

Discoveries

How do cold ions slide May 24th, 2013

Gold nanocrystal vibration captured on billion-frames-per-second film May 23rd, 2013

Whirlpools on the Nanoscale Could Multiply Magnetic Memory: At the Advanced Light Source, Berkeley Lab scientists join an international team to control spin orientation in magnetic nanodisks May 22nd, 2013

Bacterial spare parts filter antibiotic residue from groundwater May 22nd, 2013

Announcements

How do cold ions slide May 24th, 2013

Heinrich Rohrer dies at 79; a father of nanotechnology: With IBM colleague Gerd Binnig, Rohrer invented the scanning tunneling microscope, which can show individual atoms on a surface and move them around May 23rd, 2013

Gold nanocrystal vibration captured on billion-frames-per-second film May 23rd, 2013

Glowing Plant Releases Maker Kit, Enabling Anyone to Make a Glowing Plant at Home: Glowing Plant seeks funds via crowdfunding and raises almost $400,000 May 23rd, 2013

Tools

Heinrich Rohrer dies at 79; a father of nanotechnology: With IBM colleague Gerd Binnig, Rohrer invented the scanning tunneling microscope, which can show individual atoms on a surface and move them around May 23rd, 2013

Gold nanocrystal vibration captured on billion-frames-per-second film May 23rd, 2013

Researchers Stitch Defects into the World’s Thinnest Semiconductor May 22nd, 2013

Whirlpools on the Nanoscale Could Multiply Magnetic Memory: At the Advanced Light Source, Berkeley Lab scientists join an international team to control spin orientation in magnetic nanodisks May 22nd, 2013

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project








abbigliamento uomo
Computer Accessories
© Copyright 1999-2013 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE