Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > News > White light microscope

March 1st, 2009

White light microscope

Abstract:
Silver nanoparticles that can generate white light could improve microscopy in research into cancer and bone diseases according to a paper in the March issue of Nano Letters.

Optical microscopy is commonly thought to use optical transmission measurements, whereas most modern microscopists working with contemporary high-resolution microscopes use fluorescence. But, fluorescence has its limitations.

Powerful as it is, fluorescence microscopy has a fatal flaw - the need to treat any specimen with fluorescent dyes or stains. The application of these dyes often alters or harms tissues and can kill living cells. So, although fluorescence microscopy is unsurpassed in acquisition speed and spatial resolution it is severely limited in this sense.

John Lupton and colleagues, Debansu Chaudhuri, Jeremy Galushs, Manfred Walter, Nicholas Borys, and Michael Bartl in the Department of Physics and Department of Chemistry, at the University of Utah, Salt Lake City, hope to circumvent this problem without resorting to old-style microscopy.

They have worked clusters of silver nanoparticles. Silver nanoparticle films have been used for single molecule surface-enhanced Raman scattering (SERS) studies before with one- or two-photon excitation. They can thus act as a tuneable beacon of light for transmission microscopy carried out at resolutions below the diffraction limit. This limit normally stymies conventional microscopy. The researchers suggest that their success could allow researchers to investigate cancerous tissues, diseased bone and other diffuse materials in unprecedented detail and without dyes to damage the sample.

Source:
spectroscopynow.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

The Hiden EQP Plasma Diagnostic with on-board MCA July 22nd, 2014

Bruker Awarded Fourth PeakForce Tapping Patent: AFM Mode Uniquely Combines Highest Resolution Imaging and Material Property Mapping July 22nd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

Penn Study: Understanding Graphene’s Electrical Properties on an Atomic Level July 22nd, 2014

Imaging

Bruker Awarded Fourth PeakForce Tapping Patent: AFM Mode Uniquely Combines Highest Resolution Imaging and Material Property Mapping July 22nd, 2014

Discoveries

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

Penn Study: Understanding Graphene’s Electrical Properties on an Atomic Level July 22nd, 2014

NUS scientists use low cost technique to improve properties and functions of nanomaterials: By 'drawing' micropatterns on nanomaterials using a focused laser beam, scientists could modify properties of nanomaterials for effective applications in photonic and optoelectric applicat July 22nd, 2014

Oregon chemists eye improved thin films with metal substitution: Solution-based inorganic process could drive more efficient electronics and solar devices July 21st, 2014

Announcements

Nanometrics Announces Upcoming Investor Events July 22nd, 2014

Bruker Awarded Fourth PeakForce Tapping Patent: AFM Mode Uniquely Combines Highest Resolution Imaging and Material Property Mapping July 22nd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

Penn Study: Understanding Graphene’s Electrical Properties on an Atomic Level July 22nd, 2014

Tools

The Hiden EQP Plasma Diagnostic with on-board MCA July 22nd, 2014

Nanometrics Announces Upcoming Investor Events July 22nd, 2014

Bruker Awarded Fourth PeakForce Tapping Patent: AFM Mode Uniquely Combines Highest Resolution Imaging and Material Property Mapping July 22nd, 2014

Dongbu HiTek Unveils Low-Voltage BCDMOS Process for Efficient Power Management in Smart Phones and Tablet Computers July 21st, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE