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August 21st, 2008
Septicaemia causing bacteria take a blow from two different types of antibacterial nanoparticles, made by scientists working independently in the UK and Korea.
With around 80% of the infections that patients pick up in hospital associated with bacteria on the surface of medical devices and biomaterials, effective antibacterial agents are highly sought after. Nanoparticle-based agents, often applied as coatings, have shown recent promise in delivering improved sterility against a wide range of bacterial strains.
Free silver nanoparticles show good antimicrobial activity, exhibiting both size- and shape-dependent microbiological activity. But, these free nanoparticles are unsuitable for some applications like wound dressings because of their sensitivity to light and temperature. They also form aggregates, which reduce dissolution rates and efficacy.
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