- About Us
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
For millions of years nature has been optimizing DNA - in all living creatures this biomolecule is responsible for storing genetic information. Now a research project supervised by Dr. Jens Müller from the Chair of Bioinorganic Chemistry at TU Dortmund, puts the long chain molecule into a new context.
Detached from its biological origin, artificial DNA double helices were modified in such a way that the evolutionarily optimized biomolecule can also be used as a key structural element for the arrangement of metal ions. There are numerous potential applications of this basic research. With this method, for example, molecular wires or the smallest magnets could be developed to be used in nanotechnology. Moreover, the scientists think about using it as catalysts, in medicine or as sensors.
In the context of the five-year project, the scientists succeeded in developing numerous so-called "metal-ion-mediated base pairs" . By choosing the DNA sequence - the configuration of the single structural elements - the scientists can precisely influence the characteristics of the artificial "metallized" DNA. That is how, for example, the synthesis of a double helix with 19 consecutive meta-ion-mediated base pairs - the longest metal-modified DNA of this type ever reported - was done.
Within the scope of the Emmy Noether-Program, the project "Novel Metalated Base Pairs and Other Unusual DNA Motifs" has been funded with overall 530.000 Euros since August 2002. The Emmy Noether-Program is intended to support young scientists and enable them to become scientifically independent at an early stage. In this respect the Dortmund project is a total success with one habilitation thesis, two doctoral theses and five diploma theses. In addition to that, the results can be found in eleven publications in science journals.
For more information, please click here
Copyright © Technical University DortmundIf you have a comment, please Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
|Related News Press|
News and information
Kalam: versatility personified August 1st, 2015
March 2016; 6th Int'l Conference on Nanostructures in Iran July 29th, 2015
European Technology Platform for Nanomedicine and ENATRANS European Consortium Launch the 2nd edition of the Nanomedicine Award: The Award to be presented at BIO-Europe conference in Munich, November 2015 July 30th, 2015
New computer model could explain how simple molecules took first step toward life: Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules July 28th, 2015
Spintronics: Molecules stabilizing magnetism: Organic molecules fixing the magnetic orientation of a cobalt surface/ building block for a compact and low-cost storage technology/ publication in Nature Materials July 25th, 2015