Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > News > DNA cages change size on demand

February 4th, 2008

DNA cages change size on demand

Abstract:
UK and German scientists have designed dynamic DNA cages which expand or contract on demand - and could be used to deliver drugs, or be the moving parts of nanomachines.

Researchers working with DNA have coaxed the strands into various impressive structures over the last two decades - including cubes, prisms, tetrahedra, and other exotic polyhedra. But these have usually been rigid and static: each edge consisting of a short double-stranded DNA segment.

But now, researchers based at the Universities of Oxford and Bielefield have built tetrahedra with one unusual edge that includes a single-stranded segment of DNA in its middle section[1]. This segment normally bunches up into a hairpin structure, but it straightens out - thus lengthening the entire edge - when it binds to a complementary single-stranded DNA segment.

By 'fuelling' the tetrahedra with the requisite complementary DNA segment, the researchers were able to expand the cage. Conversely, when they added 'anti-fuel' strands, they stuck to 'fuelling' DNA, pulling it away from the edge of the cage and making it contract again. The team also made a tetrahedron with two variable-length edges, which could independently expand or contract - dramatically changing the shape of the cage.

Source:
rsc.org

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

A new, tunable device for spintronics: An international team of scientists including physicist Jairo Sinova from the University of Mainz realises a tunable spin-charge converter made of GaAs August 29th, 2014

Nanoscale assembly line August 29th, 2014

New analytical technology reveals 'nanomechanical' surface traits August 29th, 2014

New Vice President Takes Helm at CNSE CMOST: Catherine Gilbert To Lead CNSE Children’s Museum of Science and Technology Through Expansion And Relocation August 29th, 2014

Discoveries

A new, tunable device for spintronics: An international team of scientists including physicist Jairo Sinova from the University of Mainz realises a tunable spin-charge converter made of GaAs August 29th, 2014

Nanoscale assembly line August 29th, 2014

Copper shines as flexible conductor August 29th, 2014

Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices August 28th, 2014

Announcements

A new, tunable device for spintronics: An international team of scientists including physicist Jairo Sinova from the University of Mainz realises a tunable spin-charge converter made of GaAs August 29th, 2014

Nanoscale assembly line August 29th, 2014

New analytical technology reveals 'nanomechanical' surface traits August 29th, 2014

New Vice President Takes Helm at CNSE CMOST: Catherine Gilbert To Lead CNSE Children’s Museum of Science and Technology Through Expansion And Relocation August 29th, 2014

Nanobiotechnology

Nanoscale assembly line August 29th, 2014

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Сalculations with Nanoscale Smart Particles August 19th, 2014

Interaction between Drug, DNA for Designing Anticancer Drugs Studied in Iran August 17th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE