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October 25th, 2007

New imaging technique ensures rapid profiling of autoantibodies in rheumatoid arthritis

Abstract:
Using a new imaging technique, a fast and accurate profile of autoantibodies present in the blood serum of rheumatic patients can be made. This profile can give valuable information about the progress of the disease. A unique feature of this so-called Surface Plasmon Resonance (SPR) technique is that it directly tests on blood serum, without complex preprocessing. A special chip will enable many parallel tests. Scientists from the University of Twente and the Radboud University Nijmegen, both in The Netherlands, will publish about the new imaging technique in the Journal of the American Chemical Society (JACS).

The research was led by dr. Richard Schasfoort of the BIOS Lab-on-a-chip group, part of the MESA+ Institute for Nanotechnology of the University of Twente. He has closely cooperated with the Biomolecular Chemistry group of the Radboud University Nijmegen, of Professor Ger Pruijn. The research has been financed by the Dutch Technology Foundation (STW) within a project called ‘Proteomics on a chip for monitoring autoimmune diseases'.

Source:
nanowerk.com

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