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Home > News > UT-ORNL Governor's Chair makes discovery in protein folding

October 6th, 2007

UT-ORNL Governor's Chair makes discovery in protein folding

Abstract:
A team led by biophysicist Jeremy Smith of UT and Oak Ridge National Laboratory (ORNL) has taken a step toward discovering how proteins fold into unique, three-dimensional shapes.

The team used ORNL's Cray XT4 Jaguar supercomputer as well as computer systems in Italy and Germany to determine that the folding of proteins is affected by how they interact with water.

"Understanding the mechanism by which proteins fold up into unique three-dimensional architectures is a holy grail in molecular biology," explained Smith, who holds the first UT-ORNL Governor's Chair and is a member of the Biochemistry and Molecular Biology Department at UT.

Source:
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